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產(chǎn)品概述
名稱 | PC-12(Undifferentiated) (大鼠腎上腺嗜鉻細(xì)胞瘤細(xì)胞(未分化)) (種屬鑒定正確) |
種屬 | 大鼠 |
生長(zhǎng)特性 | 疏松貼壁 |
細(xì)胞形態(tài) | 圓形 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:2-1:4 |
推薦換液頻率 | 2-3次/周 |
注意事項(xiàng) | 1.PC-12(Undifferentiated)細(xì)胞正常生長(zhǎng)狀態(tài)為懸浮聚團(tuán),若需要用NGF誘導(dǎo)時(shí),需要使用多聚-L-賴氨酸溶液(貨號(hào) PB180523)包被培養(yǎng)瓶后促使細(xì)胞貼壁。2.Undifferentiated、Low differentiation和High differentiation的區(qū)別:Undifferentiated的PC-12從形態(tài)上看是圓形的,聚團(tuán)生長(zhǎng)的漂浮細(xì)胞;Low differentiation的成多角形,有較短的突起;High differentiation的細(xì)胞有多個(gè)突起,突起數(shù)目不等,突觸較長(zhǎng),類似神經(jīng)元軸突。3.Low differentiation和High differentiation是在Undifferentiated的PC-12基礎(chǔ)上誘導(dǎo)產(chǎn)生的,Low differentiation和High differentiation指的與神經(jīng)細(xì)胞表型的相似程度,High differentiation更接近神經(jīng)細(xì)胞表型。 |
背景描述 | PC-12(Undifferentiated)細(xì)胞是來自能移植的雄性大鼠腎上腺嗜鉻細(xì)胞瘤。PC-12(Undifferentiated)細(xì)胞表達(dá)神經(jīng)生長(zhǎng)因子(NGF)受體,NGF可誘導(dǎo)產(chǎn)生神經(jīng)表型。PC-12(Undifferentiated)細(xì)胞不合成腎上腺素。 |
年齡(性別) | 雄性 |
組織來源 | 腎上腺嗜鉻細(xì)胞瘤 |
細(xì)胞類型 | 腫瘤細(xì)胞 |
腫瘤類型 | 嗜鉻細(xì)胞瘤細(xì)胞 |
種屬鑒定
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種屬鑒定圖
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參考文獻(xiàn)
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Modular Design of Lipopeptide-Based Organ-Specific Targeting (POST) Lipid Nanoparticles for Highly Efficient RNA Delivery (2025-02-09)
期刊:ADVANCED MATERIALS
影響因子 :27.4
引用產(chǎn)品: A549 [A-549] 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , PC-12 (Low differentiation) 細(xì)胞 , 4T1 細(xì)胞 , RAW 264.7 細(xì)胞
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A novel supramolecular nanodrugs for improving the cognitive function of schizophrenia by protecting active lactone of arecoline (2025-01-17)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2025.117845
影響因子 :6.9
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞 , bEnd.3 [BEND3] 細(xì)胞 , Neuro-2a [N2a; Neuro-2a] 細(xì)胞
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Volatile oils of Schisandra chinensis (Turcz.) Baill alleviates Parkinson's disease by activating the Nrf2 pathway to positively regulate autophagy and oxidative stress (2025-02-19)
期刊:BIOORGANIC CHEMISTRY
DOI:10.1016/j.bioorg.2025.108277
影響因子 :4.5
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Gen inhibiting the Wnt/Ca2+ signaling pathway alleviates cerebral ischemia/reperfusion injury (2025-02-07)
期刊:Scientific Reports
DOI:10.1038/s41598-025-88136-8
影響因子 :3.8
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Axon-like aligned conductive CNT/GelMA hydrogel fibers combined with electrical stimulation for spinal cord injury recovery (2024-02-22)
期刊:Bioactive Materials
DOI:10.1016/j.bioactmat.2024.01.021
影響因子 :18.9
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Dual-layer microneedles with NO/O2 releasing for diabetic wound healing via neurogenesis, angiogenesis, and immune modulation (2024-12-16)
期刊:Bioactive Materials
DOI:10.1016/j.bioactmat.2024.12.012
影響因子 :18.0
引用產(chǎn)品: NCTC clone 929 [L cell, L-929] 細(xì)胞 , PC-12 (Low differentiation) 細(xì)胞 , 人臍靜脈內(nèi)皮細(xì)胞
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A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease (2024-01-24)
期刊:Nature Communications
DOI:10.1038/s41467-024-44737-x
影響因子 :16.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , BV2 細(xì)胞 , SH-SY5Y [SHSY-5Y] 細(xì)胞 , Neuro-2a [N2a; Neuro-2a] 細(xì)胞
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Enzyme-immobilized nanoclay hydrogel simultaneously reduces inflammation and scar deposition to treat spinal cord injury (2024-02-13)
期刊:CHEMICAL ENGINEERING JOURNAL
影響因子 :15.1
引用產(chǎn)品: RAW 264.7細(xì)胞專用培養(yǎng)基 , BV2細(xì)胞專用培養(yǎng)基 (DMEM) , PC-12 (Undifferentiated) 細(xì)胞 , RAW 264.7 細(xì)胞 , BV2 細(xì)胞
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Live-cell imaging of human apurinic/apyrimidinic endonuclease 1 in the nucleus and nucleolus using a chaperone@DNA probe (2024-03-30)
期刊:NUCLEIC ACIDS RESEARCH
影響因子 :14.9
引用產(chǎn)品: MCF7 [MCF-7] 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞 , PC-12 (High differentiation)細(xì)胞專用培養(yǎng)基
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pH-responsive coacervate with adrenergic nerve blockade function inhibits triple-negative breast cancer metastasis by blocking nerve-tumor-immune loop (2024-06-10)
期刊:CHEMICAL ENGINEERING JOURNAL
影響因子 :13.3
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Mechanisms of neural infiltration-mediated tumor metabolic reprogramming impacting immunotherapy efficacy in non-small cell lung cancer (2024-10-10)
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-024-03202-9
影響因子 :11.4
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞 , 多聚-L-賴氨酸溶液(10×)
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Repair spinal cord injury with a versatile anti-oxidant and neural regenerative nanoplatform (2024-06-20)
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-024-02610-5
影響因子 :10.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , 人臍靜脈內(nèi)皮細(xì)胞
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Molecular insights into vasicine and butyrylcholinesterase interactions: A complimentary biophysical, multi-spectroscopic, and computational study (2024-12-27)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2024.139253
影響因子 :7.7
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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A novel NIR fluorescent probe for copper(II) imaging in Parkinson's disease mouse brain (2024-07-22)
期刊:Chemical Science
影響因子 :7.6
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞
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CircMETTL9 targets CCAR2 to induce neuronal oxidative stress and apoptosis via mitochondria-mediated pathways following traumatic brain injury (2024-12-19)
期刊:FREE RADICAL BIOLOGY AND MEDICINE
DOI:10.1016/j.freeradbiomed.2024.12.041
影響因子 :7.1
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞 , SH-SY5Y [SHSY-5Y] 細(xì)胞
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Discovery of 4-(Arylethynyl)piperidine Derivatives as Potent Nonsaccharide O-GlcNAcase Inhibitors for the Treatment of Alzheimer’s Disease (2024-08-07)
期刊:JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1021/acs.jmedchem.4c01132
影響因子 :6.8
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞 , 特級(jí)胎牛血清 , SH-SY5Y [SHSY-5Y] 細(xì)胞
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Natural Product Virtual-Interact-Phenotypic Target Characterization: A Novel Approach Demonstrated with Salvia Miltiorrhiza Extract (2024-09-16)
期刊:Journal of Pharmaceutical Analysis
DOI:10.1016/j.jpha.2024.101101
影響因子 :6.1
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞
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Cerium Oxide-Modified Pd Nanosheets Encapsulated by Red Blood Cell Membranes with High-Efficiency RONS Scavenging for Depression Treatment (2024-10-14)
期刊:Nanoscale
影響因子 :5.8
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞 , NCTC clone 929 [L cell, L-929] 細(xì)胞 , bEnd.3 [BEND3] 細(xì)胞
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Activation of STING signaling aggravates chronic alcohol exposure-induced cognitive impairment by increasing neuroinflammation and mitochondrial apoptosis (2024-03-22)
期刊:CNS Neuroscience & Therapeutics
影響因子 :5.5
引用產(chǎn)品: BV2 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞
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Nasal administration of Xingnaojing biomimetic nanoparticles for the treatment of ischemic stroke (2024-10-12)
期刊:INTERNATIONAL JOURNAL OF PHARMACEUTICS
DOI:10.1016/j.ijpharm.2024.124830
影響因子 :5.3
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞
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Ultrasensitive detecting of dopamine in complex components by field effect transistor sensor based on the synergistic enhancement effect and overcoming debye length limitations (2024-02-17)
期刊:Results in Physics
DOI:10.1016/j.rinp.2024.107487
影響因子 :5.3
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Nrf1 Reduces COX-2 Expression and Maintains Cellular Homeostasis After Cerebral Ischemia/Reperfusion By Targeting IL-6/TNF-α Protein Production (2024-08-05)
期刊:Journal of Neuroimmune Pharmacology
DOI:10.1007/s11481-024-10136-8
影響因子 :5.2
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞
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Regulation mechanisms of sea cucumber peptides against scopolamine-induced memory disorder and novel memory-improving peptides identification (2024-02-16)
期刊:EUROPEAN JOURNAL OF PHARMACOLOGY
DOI:10.1016/j.ejphar.2024.176430
影響因子 :5.0
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , PC-12 (Undifferentiated)細(xì)胞專用培養(yǎng)基
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Insulin-Like Growth Factor Binding Protein 2 Drives Neurodegeneration in Parkinson's Disease: Insights From In?Vivo and In?Vitro Studies (2024-10-16)
期刊:CNS Neuroscience & Therapeutics
影響因子 :4.8
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞
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Guilu Erxian Jiao remodels dendritic spine morphology through activation of the hippocampal TRPC6-CaMKIV-CREB signaling pathway and suppresses fear memory generalization in rats with post-traumatic stress disorder (2024-12-14)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影響因子 :4.8
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy (2024-11-21)
期刊:MOLECULAR NEUROBIOLOGY
DOI:10.1007/s12035-024-04635-1
影響因子 :4.6
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Irisflorentin improves functional recovery after spinal cord injury by protecting the blood–spinal cord barrier and promoting axonal growth (2024-07-10)
期刊:EXPERIMENTAL NEUROLOGY
DOI:10.1016/j.expneurol.2024.114886
影響因子 :4.6
引用產(chǎn)品: 人腦微血管內(nèi)皮細(xì)胞 , PC-12 (High differentiation) 細(xì)胞
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Sports training improves motor function after spinal cord injury by regulating microtubule dynamics (2024-11-23)
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI:10.1016/j.bbadis.2024.167587
影響因子 :4.2
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Neuroprotective effects of trigonelline in eggplant on oxidative damage of PC12 cells and cognitive impairment in aging mice (2024-09-11)
期刊:Journal of Functional Foods
影響因子 :3.8
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Chlorogenic Acid Mitigates Ferroptosis by Activating the Nrf2/GPX4 Pathway through Keap1 Blockade in Vascular Dementia Rats (2024-10-07)
期刊:JOURNAL OF FOOD BIOCHEMISTRY
影響因子 :3.5
引用產(chǎn)品: PC-12 (High differentiation) 細(xì)胞
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Two new quinoline alkaloid with neuroprotective activities from Xylaria longipes (2024-03-28)
期刊:FITOTERAPIA
DOI:10.1016/j.fitote.2024.105930
影響因子 :3.4
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Five brasilane-type sesquiterpenoids with neuroprotective activities from Xylaria nigripes (2024-12-09)
期刊:PHYTOCHEMISTRY
DOI:10.1016/j.phytochem.2024.114357
影響因子 :3.2
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Sodium para-aminosalicylic acid attenuates combined manganese/iron-induced cortical synaptic damage in rats (2024-05-23)
期刊:BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
影響因子 :3.1
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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IGFBP5 Promotes Neuronal Apoptosis in a 6-OHDA-Toxicant Model of Parkinson’s Disease by Inhibiting the Sonic Hedgehog Signaling Pathway (2024-04-02)
期刊:MEDICAL PRINCIPLES AND PRACTICE
影響因子 :2.9
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞 , SH-SY5Y [SHSY-5Y] 細(xì)胞
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MiR-335 Improves Functional Recovery in Rats After Spinal Cord Injury and Protects PC12 Cells Against Injury Via the SPI-Bax/Caspase-3 Axis (2024-01-03)
期刊:SPINE
DOI:10.1097/BRS.0000000000004862
影響因子 :2.6
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞 , 特級(jí)胎牛血清
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Lepidium meyenii (Maca) polysaccharides mitigate liver toxicity of aflatoxin B1 through activation of NRF-2/GPX and AhR/STAT3 signaling pathways (2024-10-03)
期刊:TOXICON
DOI:10.1016/j.toxicon.2024.108117
影響因子 :2.6
引用產(chǎn)品: THP-1 細(xì)胞 , Hank's平衡鹽溶液(HBSS),含鈣、鎂,不含酚紅 , PC-12 (High differentiation) 細(xì)胞 , 0.25%胰蛋白酶溶液(含EDTA,溶于PBS) , L-谷氨酰胺溶液(200 mM),100× , 特級(jí)胎牛血清 , DMEM高糖 培養(yǎng)基
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Development of Cholinesterase-Activatable Fluorescent Probes for Pesticide Residue Detection (2024-02-28)
期刊:ACS Agricultural Science & Technology
DOI:10.1021/acsagscitech.3c00466
影響因子 :2.5
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , OLN93 細(xì)胞
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Luteolin Mitigates Dopaminergic Neuron Degeneration and Restrains Microglial M1 Polarization by Inhibiting Toll Like Receptor 4 (2024-09-30)
期刊:Journal of Integrative Neuroscience
影響因子 :2.5
引用產(chǎn)品: BV2 (DMEM) 細(xì)胞 , PC-12 (High differentiation) 細(xì)胞
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Celastrol alleviates secondary brain injury following intracerebral haemorrhage by inhibiting neuronal ferroptosis and blocking blood-brain barrier disruption (2024-08-06)
期刊:IBRO Neuroscience Reports
DOI:10.1016/j.ibneur.2024.08.003
影響因子 :2.0
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Photoinhibiting via simultaneous photoabsorption and free-radical reaction for high-fidelity light-based bioprinting (2023-05-27)
期刊:Nature Communications
DOI:10.1038/s41467-023-38838-2
影響因子 :16.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , Hep G2 細(xì)胞
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Individualized bio-scaffold encapsulating siPTEN-loaded exosomes for promoting neuronal regeneration in spinal cord injury (2023-12-16)
期刊:COMPOSITES PART B-ENGINEERING
DOI:10.1016/j.compositesb.2023.111146
影響因子 :13.1
引用產(chǎn)品: RPMI-1640 培養(yǎng)基 , PC-12 (Undifferentiated) 細(xì)胞 , 馬血清
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Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering (2023-11-18)
期刊:JOURNAL OF CONTROLLED RELEASE
DOI:10.1016/j.jconrel.2023.10.048
影響因子 :10.8
引用產(chǎn)品: 大鼠膀胱平滑肌細(xì)胞 , 人臍靜脈內(nèi)皮細(xì)胞 , PC-12 (Low differentiation) 細(xì)胞 , 人骨髓間充質(zhì)干細(xì)胞成骨誘導(dǎo)分化培養(yǎng)基 , 人骨髓間充質(zhì)干細(xì)胞成脂誘導(dǎo)分化培養(yǎng)基 , 人骨髓間充質(zhì)干細(xì)胞成軟骨誘導(dǎo)分化培養(yǎng)基
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Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy (2023-02-10)
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-023-01807-4
影響因子 :10.2
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , MEM (含NEAA) 培養(yǎng)基 , 特級(jí)胎牛血清
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Micro electrical fields induced MSC-sEVs attenuate neuronal cell apoptosis by activating autophagy via lncRNA MALAT1/miR-22-3p/SIRT1/AMPK axis in spinal cord injury (2023-11-27)
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-023-02217-2
影響因子 :10.2
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Plant Protein-Peptide Supramolecular Polymers with Reliable Tissue Adhesion for Surgical Sealing (2023-03-24)
期刊:Advanced Healthcare Materials
影響因子 :10.0
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis (2023-05-18)
期刊:SCIENCE OF THE TOTAL ENVIRONMENT
DOI:10.1016/j.scitotenv.2023.164078
影響因子 :9.8
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Dual-Needle Field-Effect Transistor Biosensor for In Vivo pH Monitoring (2023-06-25)
期刊:ACS Sensors
DOI:10.1021/acssensors.3c00415
影響因子 :8.9
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , PC-12(Low differentiation)細(xì)胞專用培養(yǎng)基
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An electrical microenvironment constructed based on electromagnetic induction stimulates neural differentiation (2023-03-13)
期刊:Materials Chemistry Frontiers
影響因子 :7.0
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Low beauvericin concentrations promote PC-12 cell survival under oxidative stress by regulating lipid metabolism and PI3K/AKT/mTOR signaling (2023-12-07)
期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI:10.1016/j.ecoenv.2023.115786
影響因子 :6.8
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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IL-11 ameliorates oxidative stress damage in neurons after spinal cord injury by activating the JAK/STAT signaling pathway (2023-12-30)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.111367
影響因子 :5.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Ameliorative effect of scopolamine-induced cognitive dysfunction by Fufangmuniziqi formula: The roles of alkaloids, saponins, and flavonoids (2023-06-24)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影響因子 :5.4
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Sanpian decoction ameliorates cerebral ischemia-reperfusion injury by regulating SIRT1/ERK/HIF-1α pathway through in silico analysis and experimental validation (2023-07-17)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影響因子 :5.4
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , 特級(jí)胎牛血清 , 青霉素-鏈霉素溶液 (雙抗),100×
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Indole Diterpenes from Mangrove Sediment-Derived Fungus Penicillium sp. UJNMF0740 Protect PC12 Cells against 6-OHDA-Induced Neurotoxicity via Regulating the PI3K/Akt Pathway (2023-11-14)
期刊:Marine Drugs
影響因子 :5.4
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Dandelion (Taraxacum mongolicum) Extract Alleviated H2O2-Induced Oxidative Damage: The Underlying Mechanism Revealed by Metabolomics and Lipidomics (2023-09-03)
期刊:Foods
影響因子 :5.2
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Two New Compounds from the Fungus Xylaria nigripes (2023-01-04)
期刊:MOLECULES
影響因子 :4.6
引用產(chǎn)品: 特級(jí)胎牛血清 , PC-12 (Undifferentiated) 細(xì)胞
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Gastrodin Induces Ferroptosis of Glioma Cells via Upregulation of Homeobox D10 (2023-12-13)
期刊:MOLECULES
影響因子 :4.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Characterization of Polysaccharides from the Pericarp of Zanthoxylum bungeanum Maxim by Saccharide Mapping and Their Neuroprotective Effects (2023-02-15)
期刊:MOLECULES
影響因子 :4.6
引用產(chǎn)品: DMEM高糖 培養(yǎng)基 , PC-12 (Undifferentiated) 細(xì)胞
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Enhancing both oral bioavailability and anti-ischemic stroke efficacy of ginkgolide B by preparing nanocrystals self-stabilized Pickering nano-emulsion (2023-10-21)
期刊:EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
DOI:10.1016/j.ejps.2023.106620
影響因子 :4.6
引用產(chǎn)品: MDBK [NBL-1] 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞
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Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model (2023-05-06)
期刊:NEUROCHEMICAL RESEARCH
DOI:10.1007/s11064-023-03946-4
影響因子 :4.4
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , RSC96 細(xì)胞
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Bioinformatics and experimental analyses of glutamate receptor and its targets genes in myocardial and cerebral ischemia (2023-06-02)
期刊:BMC GENOMICS
DOI:10.1186/s12864-023-09408-z
影響因子 :4.4
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Identification of ANXA3 as a biomarker associated with pyroptosis in ischemic stroke (2023-12-15)
期刊:EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI:10.1186/s40001-023-01564-y
影響因子 :4.2
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Downregulation of Preso protects against ischemic/reperfusion-mediated neuronal injury through regulating PSD95-nNOS/YAP pathways (2023-07-12)
期刊:NEUROCHEMISTRY INTERNATIONAL
DOI:10.1016/j.neuint.2023.105586
影響因子 :4.2
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Exosomes from magnetic particles-primed mesenchymal stem cells enhance neural differentiation of PC12 cells. (2023-10-16)
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e21075
影響因子 :4.0
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Overexpression of FSP1 Ameliorates ferroptosis via PI3K/ AKT /GSK3β pathway in PC12 cells with Oxygen-Glucose Deprivation/Reoxygenation (2023-07-21)
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e18449
影響因子 :4.0
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Neuroprotective methylsuccinic acid and enoic acid derivatives from the fungus Xylaria longipes (2023-03-24)
期刊:PHYTOCHEMISTRY
DOI:10.1016/j.phytochem.2023.113652
影響因子 :3.8
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , 磷酸鹽緩沖液 (PBS) 1×
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Integrated insight into the molecular mechanisms of selenium-modulated, MPP+-induced cytotoxicity in a Parkinson’s disease model (2023-05-24)
期刊:JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
DOI:10.1016/j.jtemb.2023.127208
影響因子 :3.5
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Doping Ag2S quantum dots with Pb yields significantly enhanced in vivo fluorescence imaging in the NIR-II window and comparable toxic effects (2023-07-26)
期刊:NEW JOURNAL OF CHEMISTRY
影響因子 :3.3
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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METTL3 silenced inhibited the ferroptosis development via regulating the TFRC levels in the Intracerebral hemorrhage progression (2023-04-25)
期刊:BRAIN RESEARCH
DOI:10.1016/j.brainres.2023.148373
影響因子 :2.9
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Umbilical mesenchymal stem cell-derived exosomes promote spinal cord functional recovery through the miR-146b/TLR4 -mediated NF-κB p65 signaling pathway in rats (2023-07-20)
期刊:Biochemistry and Biophysics Reports
DOI:10.1016/j.bbrep.2023.101497
影響因子 :2.7
引用產(chǎn)品: 人臍帶間充質(zhì)干細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞
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STIM2 Suppression Blocks Glial Activation to Alleviate Brain Ischemia Reperfusion Injury via Inhibition of Inflammation and Pyroptosis (2023-08-12)
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-023-00823-x
影響因子 :2.6
引用產(chǎn)品: BV2 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞
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Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2 (2023-06-30)
期刊:Journal of Stroke & Cerebrovascular Diseases
DOI:10.1016/j.jstrokecerebrovasdis.2023.107235
影響因子 :2.5
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Two pairs of new isobenzofuranone enantiomers from a soil-derived fungus Penicillium canescens DWS225 (2023-04-11)
期刊:NATURAL PRODUCT RESEARCH
DOI:10.1080/14786419.2023.2198712
影響因子 :2.2
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , 磷酸鹽緩沖液 (PBS) 1×
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Inhibition of TERC inhibits neural apoptosis and inflammation in spinal cord injury through Akt activation and p-38 inhibition via the miR-34a-5p/XBP-1 axis (2023-01-24)
期刊:Open Medicine
影響因子 :2.1
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , 馬血清
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Combining a Density Gradient of Biomacromolecular Nanoparticles with Biological Effectors in an Electrospun Fiber-Based Nerve Guidance Conduit to Promote Peripheral Nerve Repair (2022-12-09)
期刊:Advanced Science
影響因子 :17.5
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , 多聚-L-賴氨酸溶液 (10×) , PC-12 (Undifferentiated)細(xì)胞專用培養(yǎng)基
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Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice (2022-02-10)
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-04592-4
影響因子 :9.0
引用產(chǎn)品: BV2 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞
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Antidepressant-like effects of geniposide in chronic unpredictable mild stress-induced mice by regulating the circ_0008405/miR-25-3p/Gata2 and Oip5os1/miR-25-3p/Gata2 networks (2022-12-14)
期刊:PHYTOTHERAPY RESEARCH
DOI:10.1002/ptr.7702
影響因子 :6.4
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Alpiniae oxyphyllae fructus possesses neuroprotective effects on H2O2 stimulated PC12 cells via regulation of the PI3K/Akt signaling Pathway (2022-08-25)
期刊:Frontiers in Pharmacology
影響因子 :6.0
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury (2022-12-22)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2022.109616
影響因子 :5.7
引用產(chǎn)品: BV2 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞
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A Novel Based-Network Strategy to Identify Phytochemicals from Radix Salviae Miltiorrhizae (Danshen) for Treating Alzheimer’s Disease (2022-07-12)
期刊:MOLECULES
影響因子 :4.9
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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The SWGEDWGEIW from Soybean Peptides Reduce Oxidative Damage-Mediated Apoptosis in PC-12 Cells by Activating SIRT3/FOXO3a Signaling Pathway (2022-11-06)
期刊:MOLECULES
影響因子 :4.9
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Biogenic Selenium Nanoparticles Attenuate Aβ25–35-Induced Toxicity in PC12 Cells via Akt/CREB/BDNF Signaling Pathway (2022-11-26)
期刊:NEUROTOXICITY RESEARCH
DOI:10.1007/s12640-022-00590-8
影響因子 :4.0
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Protective effects of Dendrobium huoshanense polysaccharide on D-gal induced PC12 cells and aging mice, in vitro and in vivo studies (2022-11-09)
期刊:JOURNAL OF FOOD BIOCHEMISTRY
影響因子 :3.7
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Purification, Identification and Neuroprotective Effects of Proteins from Bombyx batryticatus in Glu-Stimulated PC12 Cells (2022-09-01)
期刊:Separations
DOI:10.3390/separations9090236
影響因子 :3.3
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Calycosin ameliorates spinal cord injury by targeting Hsp90 to inhibit oxidative stress and apoptosis of nerve cells (2022-11-17)
期刊:JOURNAL OF CHEMICAL NEUROANATOMY
DOI:10.1016/j.jchemneu.2022.102190
影響因子 :3.1
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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miR?222-3p reduces neuronal cell apoptosis and alleviates spinal cord injury by inhibiting Bbc3 and Bim (2022-10-31)
期刊:NEUROSCIENCE RESEARCH
DOI:10.1016/j.neures.2022.10.008
影響因子 :2.9
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Fabrication and detection of a novel hybrid conductive scaffold based on alginate/gelatin/carboxylated carbon nanotubes (Alg/Gel/mMWCNTs) for neural tissue engineering (2022-12-07)
期刊:TISSUE & CELL
DOI:10.1016/j.tice.2022.101995
影響因子 :2.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo (2022-01-01)
期刊:Anti-Cancer Drugs
DOI:10.1097/CAD.0000000000001136
影響因子 :2.3
引用產(chǎn)品: HCT 116 細(xì)胞 , A549 [A-549] 細(xì)胞 , Hep G2 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞
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Macroscopic Supramolecular Assembly Strategy to Construct 3D Biocompatible Microenvironments with Site-Selective Cell Adhesion (2021-06-11)
期刊:ACS Applied Materials & Interfaces
影響因子 :9.5
引用產(chǎn)品: MG-63 細(xì)胞 , PC-12 (Undifferentiated) 細(xì)胞 , 重組人胰島素溶液 (10mg/mL) , MEM非必需氨基酸溶液 (NEAA),100× , PUMC-HUVEC-T1 , CCC-SMC-1 細(xì)胞
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Protective effect of plastrum testudinis extract on dopaminergic neurons in a Parkinsons disease model through DNMT1 nuclear translocation and SNCAs methylation (2021-06-18)
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.111832
影響因子 :7.5
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H2O2-Stimulated PC12 Cells via Regulation of PI3K/Akt/Nrf2 Signaling Pathways (2021-07-20)
期刊:Oxidative Medicine and Cellular Longevity
影響因子 :6.5
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Neuroprotective effects of NDEELNK from sea cucumber ovum against scopolamine-induced PC12 cell damage through enhancing energy metabolism and upregulation of the PKA/BDNF/NGF signaling pathway (2021-06-22)
期刊:Food & Function
影響因子 :6.1
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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A novel nonapeptide SSDAFFPFR from Antarctic krill exerts a protective effect on PC12?cells through the BCL-XL/Bax/Caspase-3/p53 signaling pathway (2021-08-31)
期刊:Food Bioscience
DOI:10.1016/j.fbio.2021.101345
影響因子 :5.2
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Adipose Mesenchymal Stem Cell-Derived Exosomes Enhance PC12 Cell Function through the Activation of the PI3K/AKT Pathway (2021-10-15)
期刊:Stem Cells International
影響因子 :4.3
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Acupuncture Ameliorates Neuronal Cell Death, Inflammation, and Ferroptosis and Downregulated miR-23a-3p After Intracerebral Hemorrhage in Rats (2021-01-05)
期刊:Journal of Molecular Neuroscience
DOI:10.1007/s12031-020-01770-x
影響因子 :3.1
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Preparation, structural characterization and neuroprotective effects of polysaccharides from the pericarp of Zanthoxylum bungeanum Maxim against H2O2-induced oxidative damage in PC12 cells (2021-07-08)
期刊:SOUTH AFRICAN JOURNAL OF BOTANY
DOI:10.1016/j.sajb.2021.06.026
影響因子 :2.3
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Four new resorcinol derivatives with neuroprotective activities from Xylaria nigripes (2021-03-10)
期刊:Natural Product Research
DOI:10.1080/14786419.2021.1897591
影響因子 :2.2
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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microRNA-184 enhances the sensitivity of pheochromocytoma-12 cells to doxorubicin by targeting ADAM22 (2021-02-04)
期刊:Molecular & Cellular Toxicology
DOI:10.1007/s13273-021-00116-x
影響因子 :1.7
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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A value-added application of eugenol as acaricidal agent: The mechanism of action and the safety evaluation (2020-12-28)
期刊:Journal of Advanced Research
DOI:10.1016/j.jare.2020.12.010
影響因子 :10.7
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Low-glucose-sensitive TRPC6 dysfunction drives hypoglycemia-induced cognitive impairment in diabetes (2020-10-18)
期刊:Clinical and Translational Medicine
DOI:10.1002/ctm2.205
影響因子 :10.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Neuroprotective Function of a Novel Hexapeptide QMDDQ from Shrimp via Activation of the PKA/CREB/BNDF Signaling Pathway and Its Structure–Activity Relationship (2020-06-02)
期刊:Journal Of Agricultural And Food Chemistry
影響因子 :6.1
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Optimal route of gold nanoclusters administration in mice targeting Parkinson’s disease (2020-02-21)
期刊:Nanomedicine
影響因子 :5.5
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Hydroxy-α-sanshool Possesses Protective Potentials on H2O2-Stimulated PC12 Cells by Suppression of Oxidative Stress-Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway (2020-07-09)
期刊:Oxidative Medicine and Cellular Longevity
影響因子 :5.1
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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The Effect of Protein-Rich Extract from Bombyx Batryticatus against Glutamate-Damaged PC12 Cells Via Regulating γ-Aminobutyric Acid Signaling Pathway (2020-01-28)
期刊:MOLECULES
影響因子 :3.3
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Evaluation and structure–activity relationship analysis of antioxidant shrimp peptides (2019-08-16)
期刊:Food & Function
影響因子 :6.1
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Egg yolk phosphatidylcholine: Extraction, purification and its potential neuroprotective effect on PC12 cells (2019-03-28)
期刊:Journal of Functional Foods
影響因子 :5.6
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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Antiepileptic Effects of Protein-Rich Extract from Bombyx batryticatus on Mice and Its Protective Effects against H2O2-Induced Oxidative Damage in PC12 Cells via Regulating PI3K/Akt Signaling Pathways (2019-05-06)
期刊:Oxidative Medicine and Cellular Longevity
影響因子 :4.9
引用產(chǎn)品: PC-12 (Low differentiation) 細(xì)胞
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Glutamine Improves Oxidative Stress through the Wnt3a/ β-Catenin Signaling Pathway in Alzheimers Disease In Vitro and In Vivo (2019-04-16)
期刊:Biomed Research International
影響因子 :3.3
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞 , RPMI-1640 (不含L-谷氨酰胺) 培養(yǎng)基
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Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells (2019-02-22)
期刊:Neuroreport
DOI:10.1097/WNR.0000000000001180
影響因子 :1.7
引用產(chǎn)品: PC-12 (Undifferentiated) 細(xì)胞
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