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產(chǎn)品概述
| 名稱 | RSC96 (大鼠雪旺細(xì)胞) (種屬鑒定正確) |
| 別稱 | RSC 96; RSC-96 |
| 種屬 | 大鼠 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 神經(jīng)細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
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| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | RSC96細(xì)胞是原代培養(yǎng)的大鼠雪旺細(xì)胞經(jīng)長時間培養(yǎng)后自發(fā)轉(zhuǎn)化而成的。2002年12月提交到ATCC的RSC96細(xì)胞污染了支原體，RSC96細(xì)胞后代細(xì)胞通過BM細(xì)胞周期蛋白處理21天消除支原體。處理后6周，用Hoechst染色、PCR和標(biāo)準(zhǔn)培養(yǎng)測試進(jìn)行支原體檢測，結(jié)果都呈陰性。 |
| 組織來源 | 雪旺細(xì)胞 |
| 細(xì)胞類型 | 自發(fā)永生化細(xì)胞 |
| 生物安全等級 | BSL-1 |
| 受體表達(dá)情況 | Nerve growth factor receptor (Ngfr); Protein and mRNA, negative;Platelet derived growth factor receptor, alpha; negative;Platelet derived growth factor receptor, beta; negative |
| 保藏機(jī)構(gòu) | ATCC; CRL-2765 |
種屬鑒定
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種屬鑒定圖
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參考文獻(xiàn)
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Efficacy and mechanisms of concentrated growth factor on facial nerve rehabilitation in a rabbit model (2025-01-20)
期刊：Biomaterials Science
影響因子 ：5.8
引用產(chǎn)品： RSC96 細(xì)胞 , 青霉素-鏈霉素溶液（雙抗），100× , 0.25%胰蛋白酶溶液（含EDTA，溶于PBS）
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Mung Bean-Derived Carbon Dots Suppress Ferroptosis of Schwann Cells via Nrf2/HO-1/GPX4 Pathway to Promote Peripheral Nerve Repair (2025-01-15)
期刊：Biomaterials Science
影響因子 ：5.8
引用產(chǎn)品： RSC96 細(xì)胞
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Conductive polyphenol microneedles coupled with electroacupuncture to accelerate wound healing and alleviate depressive-like behaviors in diabetes (2024-11-07)
期刊：Bioactive Materials
DOI：10.1016/j.bioactmat.2024.11.001
影響因子 ：18.0
引用產(chǎn)品： RSC96 細(xì)胞
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Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (2024-12-24)
期刊：Advanced Science
影響因子 ：14.3
引用產(chǎn)品： RAW 264.7 細(xì)胞 , RSC96 細(xì)胞 , PC-12 (High differentiation) 細(xì)胞
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Pleiotropic effects of nitric oxide sustained-release system for peripheral nerve repair (2024-05-16)
期刊：Acta Biomaterialia
DOI：10.1016/j.actbio.2024.05.012
影響因子 ：9.7
引用產(chǎn)品： 小鼠雪旺氏細(xì)胞 , RSC96 細(xì)胞 , 人臍靜脈內(nèi)皮細(xì)胞
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Enhancing cellular behavior in repaired tissue via silk fibroin-integrated triboelectric nanogenerators (2024-05-24)
期刊：Microsystems & Nanoengineering
DOI：10.1038/s41378-024-00694-5
影響因子 ：7.9
引用產(chǎn)品： EA.hy926 細(xì)胞 , RSC96 細(xì)胞 , NIH/3T3 細(xì)胞
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Digital light processing bioprinting neural systems with porous hydrogel in structure and function for disease models (2024-12-10)
期刊：Cell Reports Physical Science
DOI：10.1016/j.xcrp.2024.102311
影響因子 ：7.9
引用產(chǎn)品： HT22 細(xì)胞 , C8-D1A 細(xì)胞 , RSC96 細(xì)胞
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Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson’s disease autonomic dysfunction (2024-01-26)
期刊：Cell Death Discovery
DOI：10.1038/s41420-024-01824-8
影響因子 ：7.0
引用產(chǎn)品： RSC96 細(xì)胞 , DMEM高糖 培養(yǎng)基
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Xiaoke Bitong capsule alleviates inflammatory impairment via inhibition of the TNF signaling pathway to against diabetic peripheral neuropathy (2024-07-09)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155867
影響因子 ：6.7
引用產(chǎn)品： RSC96 細(xì)胞
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Acetyl-11-keto-beta-boswellic acid modulates macrophage polarization and Schwann cell migration to accelerate spinal cord injury repair in rats (2024-03-02)
期刊：CNS Neuroscience & Therapeutics
影響因子 ：5.5
引用產(chǎn)品： RAW 264.7 細(xì)胞 , RSC96 細(xì)胞
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Peripheral nervous system lymphatic vessels: A simple delivery route to promote nerve regeneration (2024-04-28)
期刊：EXPERIMENTAL NEUROLOGY
DOI：10.1016/j.expneurol.2024.114783
影響因子 ：4.6
引用產(chǎn)品： 人淋巴管內(nèi)皮細(xì)胞 , 人骨髓間充質(zhì)干細(xì)胞 , RSC96 細(xì)胞
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Unraveling Neurotoxicity Discrepancies: Comparative In vitro and In vivo Analysis of Colistin and Polymyxin B and the Underlying Mechanisms (2024-10-28)
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-024-04577-8
影響因子 ：4.6
引用產(chǎn)品： Neuro-2a [N2a; Neuro-2a] 細(xì)胞 , MEM 培養(yǎng)基 , DMEM高糖 培養(yǎng)基 , 特級胎牛血清 , RSC96 細(xì)胞
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Identification of key genes and immune infiltration of diabetic peripheral neuropathy in mice and humans based on bioinformatics analysis (2024-11-18)
期刊：Frontiers in Endocrinology
DOI：10.3389/fendo.2024.1437979
影響因子 ：3.9
引用產(chǎn)品： RSC96 細(xì)胞 , DMEM高糖完全培養(yǎng)基（含10% FBS）
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Sevoflurane impedes neuropathic pain by maintaining endoplasmic reticulum stress and oxidative stress homeostasis through inhibiting the activation of the PLCγ/CaMKII/IP3R signaling pathway (2024-07-05)
期刊：Aging-US
影響因子 ：3.9
引用產(chǎn)品： RSC96 細(xì)胞
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Melittin promotes the proliferation of Schwann cells in hyperglycemic environment by up?regulating the Crabp2/Wnt/β?catenin signaling pathway (2024-10-18)
期刊：Molecular Medicine Reports
影響因子 ：3.4
引用產(chǎn)品： RSC96 細(xì)胞 , 特級胎牛血清
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Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats (2023-11-24)
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-023-02222-5
影響因子 ：10.2
引用產(chǎn)品： RSC96 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Endothelial cell-derived exosomes boost and maintain repair-related phenotypes of Schwann cells via miR199-5p to promote nerve regeneration (2023-01-09)
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-023-01767-9
影響因子 ：10.2
引用產(chǎn)品： 人臍靜脈內(nèi)皮細(xì)胞 , RSC96 細(xì)胞
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Endogenous Electric Field-Coupled PD@BP Biomimetic Periosteum Promotes Bone Regeneration through Sensory Nerve via Fanconi Anemia Signaling Pathway (2023-01-18)
期刊：Advanced Healthcare Materials
影響因子 ：10.0
引用產(chǎn)品： RSC96 細(xì)胞
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Honokiol attenuates high glucose-induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC-1ɑ pathway in Schwann cells (2023-08-14)
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.7984
影響因子 ：7.2
引用產(chǎn)品： RSC96 細(xì)胞
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Compound Qiying Granules alleviates diabetic peripheral neuropathy by inhibiting endoplasmic reticulum stress and apoptosis (2023-07-18)
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-023-00698-3
影響因子 ：5.7
引用產(chǎn)品： RSC96 細(xì)胞
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Cisplatin causes erectile dysfunction by decreasing endothelial and smooth muscle content and inducing cavernosal nerve senescence in rats (2023-01-25)
期刊：Frontiers in Endocrinology
DOI：10.3389/fendo.2023.1096723
影響因子 ：5.2
引用產(chǎn)品： RSC96 細(xì)胞
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The CXCL12-CXCR4-NLRP3 axis promotes Schwann cell pyroptosis and sciatic nerve demyelination in rats (2023-07-27)
期刊：CLINICAL AND EXPERIMENTAL IMMUNOLOGY
影響因子 ：4.6
引用產(chǎn)品： RSC96 細(xì)胞
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Evodiamine attenuates oxidative stress and ferroptosis by inhibiting the MAPK signaling to improve bortezomib-induced peripheral neurotoxicity (2023-11-27)
期刊：ENVIRONMENTAL TOXICOLOGY
影響因子 ：4.5
引用產(chǎn)品： 大鼠背根神經(jīng)元細(xì)胞 , RSC96 細(xì)胞
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Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model (2023-05-06)
期刊：NEUROCHEMICAL RESEARCH
DOI：10.1007/s11064-023-03946-4
影響因子 ：4.4
引用產(chǎn)品： PC-12 (Undifferentiated) 細(xì)胞 , RSC96 細(xì)胞
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Formononetin attenuates high glucose-induced neurotoxicity by negatively regulating oxidative stress and mitochondrial dysfunction in Schwann cells via activation of SIRT3 (2023-11-07)
期刊：FOOD AND CHEMICAL TOXICOLOGY
影響因子 ：4.3
引用產(chǎn)品： RSC96 細(xì)胞
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Aptamer engineering exosomes loaded on biomimetic periosteum to promote angiogenesis and bone regeneration by targeting injured nerves via JNK3 MAPK pathway (2022-09-20)
期刊：Materials Today Bio
DOI：10.1016/j.mtbio.2022.100434
影響因子 ：10.8
引用產(chǎn)品： RSC96 細(xì)胞 , 人臍靜脈內(nèi)皮細(xì)胞
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