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MDA-MB-453 (人乳腺癌細(xì)胞) (STR鑒定正確)
貨號(hào):CL-0152
規(guī)格:1×10?cells/T25培養(yǎng)瓶
價(jià)格: ¥1800
生長培養(yǎng)基:Leibovitz's L-15+10% FBS+1% P/S
產(chǎn)品概述
名稱 | MDA-MB-453 (人乳腺癌細(xì)胞) (STR鑒定正確) |
別稱 | MDA-MB 453; MDA MB 453; MDA-MB453; MDAMB453; MDA-453; MDA453; MD Anderson-Metastatic Breast-453 |
種屬 | 人類 |
生長特性 | 半貼半懸 |
細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
生長培養(yǎng)基:
培養(yǎng)條件:
氣相:空氣,100%, 溫度:37℃
|
培養(yǎng)方案B(可選) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:2-1:4 |
推薦換液頻率 | 2-3次/周 |
注意事項(xiàng) | 1.該細(xì)胞推薦使用Leibovitz's L-15培養(yǎng)基進(jìn)行培養(yǎng),Leibovitz's L-15不可以通入二氧化碳,會(huì)產(chǎn)生細(xì)胞毒性;2.如您沒有無二氧化碳的培養(yǎng)箱,可使用DMEM替代Leibovitz's L-15,使用DMEM培養(yǎng)基時(shí)即可正常通入5%二氧化碳;3.配套專用培養(yǎng)基默認(rèn)Leibovitz's L-15配置,如需DMEM配方,請(qǐng)聯(lián)系銷售下單備注更改。 |
背景描述 | MDA-MB-453細(xì)胞是由R·Cailleau等在1976年從一位48歲女性腫瘤轉(zhuǎn)移患者胸水中建立的細(xì)胞株,其它轉(zhuǎn)移灶包括淋巴結(jié)、腦和胸水及心包腔積水;MDA-MB-453細(xì)胞過表達(dá)FGF受體。 |
年齡(性別) | 女性,48歲 |
組織來源 | 乳腺;源自轉(zhuǎn)移部位:胸腔積液 |
細(xì)胞類型 | 腫瘤細(xì)胞 |
腫瘤類型 | 乳腺癌細(xì)胞 |
生物安全等級(jí) | BSL-1 |
倍增時(shí)間 | ~26-38 hours |
致瘤性 | No, in immunosuppressed mice.Yes, in semisolid medium. |
受體表達(dá)情況 | fibroblast growth factor (FGF), expressed |
保藏機(jī)構(gòu) | ATCC; HTB-131 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 10,12 D2S1338 23,24 D3S1358 15 D5S818 11 D7S820 10 D8S1179 10,12 D13S317 12 D16S539 9 D18S51 15,20 D19S433 13,14 D21S11 29,31 FGA 18,23 PentaD 9,10 PentaE 11 TH01 6 TPOX 10 vWA 17,18 D6S1043 11,18 D12S391 18,21 D2S441 10 -
STR鑒定圖
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參考文獻(xiàn)
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Micropeptide hSPAR regulates glutamine levels and suppresses mammary tumor growth via a TRIM21-P27KIP1-mTOR axis (2025-01-28)
期刊:EMBO JOURNAL
DOI:10.1038/s44318-024-00359-z
影響因子 :9.4
引用產(chǎn)品: RPMI-1640 培養(yǎng)基 , 293T [HEK-293T] 細(xì)胞 , MDA-MB-231 細(xì)胞 , MDA-MB-468-06 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MCF 10A細(xì)胞專用培養(yǎng)基 , MCF7 [MCF-7]細(xì)胞專用培養(yǎng)基 , MCF 10A 細(xì)胞
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SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer (2025-02-03)
期刊:NEOPLASIA
影響因子 :6.3
引用產(chǎn)品: ZR-75-1 細(xì)胞 , HCC1954 細(xì)胞 , MDA-MB-453 細(xì)胞 , 青霉素-鏈霉素溶液(雙抗),100×
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miR-223-3p Targets KIF4A and Promotes the Oxidative Stress-Mediated Apoptosis of Breast Cancer Cells (2025-02-06)
期刊:CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
影響因子 :2.4
引用產(chǎn)品: MDA-MB-157 細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-231 細(xì)胞 , MCF 10A 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , T-47D 細(xì)胞
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Identification of Piperazinyl–Difluoro-indene Derivatives Containing Pyridyl Groups as Potent FGFR Inhibitors against FGFR Mutant Tumor: Design, Synthesis, and Biological Evaluation (2024-01-31)
期刊:JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1021/acs.jmedchem.3c02040
影響因子 :7.3
引用產(chǎn)品: KMS-11 細(xì)胞 , MDA-MB-453 細(xì)胞
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RERE-AS1 enhances the effect of CDK4/6 inhibitor Ribociclib and suppresses malignant phenotype in breast cancer via MEK/ERK pathway (2024-11-22)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-024-05828-x
影響因子 :6.1
引用產(chǎn)品: 293T [HEK-293T] 細(xì)胞 , T-47D 細(xì)胞 , Hs 578T 細(xì)胞 , MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞 , BT-549 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MDA-MB-468-06 細(xì)胞 , BT-474 [BT474] 細(xì)胞
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Nifuratel Induces Triple-Negative Breast Cancer Cell G2/M Phase Block and Apoptosis by Regulating GADD45A (2024-09-26)
期刊:Pharmaceuticals
影響因子 :4.3
引用產(chǎn)品: HCC1806 細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-468-06 細(xì)胞 , MDA-MB-231 細(xì)胞 , BT-549 細(xì)胞
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Machine learning-guided synthesis of nanomaterials for breast cancer therapy (2024-10-28)
期刊:Scientific Reports
DOI:10.1038/s41598-024-76924-7
影響因子 :3.8
引用產(chǎn)品: MDA-MB-453 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞
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LncRNA DDX11-AS1 promotes breast cancer progression by targeting the miR-30c-5p/MTDH axis (2024-11-05)
期刊:Scientific Reports
DOI:10.1038/s41598-024-78413-3
影響因子 :3.8
引用產(chǎn)品: MCF7 [MCF-7] 細(xì)胞 , BT-549 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , MCF 10A 細(xì)胞 , McCoy's 5A 培養(yǎng)基 , MDA-MB-453 細(xì)胞 , MDA-MB-231 細(xì)胞
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The study on circRNA profiling uncovers the regulatory function of the hsa_circ_0059665/miR-602 pathway in breast cancer (2024-09-04)
期刊:Scientific Reports
DOI:10.1038/s41598-024-71505-0
影響因子 :3.8
引用產(chǎn)品: BT-549 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MDA-MB-231 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , MDA-MB-453 細(xì)胞
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EP300 promotes tumor stemness via epigenetic activation of CRISP3 leading to lobaplatin resistance in triple-negative breast cancer (2024-06-16)
期刊:Human Cell
DOI:10.1007/s13577-024-01091-w
影響因子 :3.4
引用產(chǎn)品: RPMI-1640 培養(yǎng)基 , Leibovitz's L-15 培養(yǎng)基 , MDA-MB-453 細(xì)胞 , SUM159PT 細(xì)胞
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CD8+ T cell?related KCTD5 contributes to malignant progression and unfavorable clinical outcome of patients with triple?negative breast cancer (2024-07-12)
期刊:Molecular Medicine Reports
影響因子 :3.4
引用產(chǎn)品: DMEM高糖 培養(yǎng)基 , MDA-MB-453 細(xì)胞 , 青霉素-鏈霉素溶液(雙抗),100× , MDA-MB-231 細(xì)胞 , 特級(jí)胎牛血清 , MCF 10A 細(xì)胞
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Maydisens, Sesterterpenoids with Anti-MDR Activity from Bipolaris maydis (2024-10-02)
期刊:JOURNAL OF NATURAL PRODUCTS
DOI:10.1021/acs.jnatprod.4c00658
影響因子 :3.3
引用產(chǎn)品: DMEM高糖 培養(yǎng)基 , 特級(jí)胎牛血清 , Hep G2 細(xì)胞 , MDA-MB-453 細(xì)胞 , C4-2 細(xì)胞 , A549 [A-549] 細(xì)胞
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LncRNA PTPRG-AS1 Promotes Breast Cancer Progression by Modulating the miR-4659a-3p/QPCT Axis (2024-10-04)
期刊:OncoTargets and Therapy
影響因子 :2.7
引用產(chǎn)品: BT-549 細(xì)胞 , MCF 10A 細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-231 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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circ_JMJD1C expedites breast cancer progression by regulating miR-182-5p/JMJD1C/SOX4 axis (2024-03-31)
期刊:CELLULAR AND MOLECULAR BIOLOGY
影響因子 :1.5
引用產(chǎn)品: MCF7 [MCF-7] 細(xì)胞 , BT-549 細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-231 細(xì)胞 , MCF 10A 細(xì)胞
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A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis (2023-03-25)
期刊:Cancer Cell International
DOI:10.1186/s12935-023-02895-w
影響因子 :5.8
引用產(chǎn)品: MCF 10A 細(xì)胞 , BT-474 [BT474] 細(xì)胞 , BT-549 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MDA-MB-231 細(xì)胞 , MDA-MB-231 細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-453 細(xì)胞 , T-47D 細(xì)胞 , MCF 10A細(xì)胞專用培養(yǎng)基 , BT-474 [BT474]細(xì)胞專用培養(yǎng)基 , BT-549細(xì)胞專用培養(yǎng)基 , MCF7 [MCF-7]細(xì)胞專用培養(yǎng)基 , MDA-MB-231細(xì)胞專用培養(yǎng)基 (L15) , MDA-MB-231細(xì)胞專用培養(yǎng)基 (DMEM) , MDA-MB-453細(xì)胞專用培養(yǎng)基 (L15)
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A Novel Optical Fiber Terahertz Biosensor Based on Anti-Resonance for The Rapid and Nondestructive Detection of Tumor Cells (2023-10-23)
期刊:Biosensors-Basel
影響因子 :5.4
引用產(chǎn)品: MDA-MB-453 細(xì)胞 , MDA-MB-231 細(xì)胞 , BT-474 [BT474] 細(xì)胞
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Potentiated effects of lactate receptor GPR81 on immune microenvironment in breast cancer (2023-05-30)
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23582
影響因子 :4.6
引用產(chǎn)品: BT-549 細(xì)胞 , MDA-MB-453 細(xì)胞 , THP-1 細(xì)胞
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Enantiomeric α-pyrone derivatives with immunosuppressive activity from Talaromyces adpressus (2023-11-27)
期刊:PHYTOCHEMISTRY
DOI:10.1016/j.phytochem.2023.113931
影響因子 :3.8
引用產(chǎn)品: MDA-MB-453 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , VCaP 細(xì)胞
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Isopimaric acid, an ion channel regulator, regulates calcium and oxidative phosphorylation pathways to inhibit breast cancer proliferation and metastasis (2023-02-06)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2023.116415
影響因子 :3.8
引用產(chǎn)品: MDA-MB-231 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MDA-MB-468 細(xì)胞 , HCC1937 細(xì)胞 , MDA-MB-453 細(xì)胞 , 4T1 細(xì)胞 , MCF 10A 細(xì)胞 , Annexin V-FITC/ PI熒光雙染細(xì)胞凋亡檢測(cè)試劑盒
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Identification of TUBB2A as a Cancer-Immunity Cycle-Related Therapeutic Target in Triple-Negative Breast Cancer (2023-09-24)
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-023-00880-2
影響因子 :2.6
引用產(chǎn)品: MCF 10A 細(xì)胞 , MDA-MB-231 細(xì)胞 , MDA-MB-453 細(xì)胞 , DMEM高糖 培養(yǎng)基 , 特級(jí)胎牛血清
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Asiaticoside hampers epithelial–mesenchymal transition by promoting PPARG expression and suppressing P2RX7-mediated TGF-β/Smad signaling in triple-negative breast cancer (2022-11-28)
期刊:PHYTOTHERAPY RESEARCH
DOI:10.1002/ptr.7692
影響因子 :6.4
引用產(chǎn)品: 人乳腺上皮細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-231細(xì)胞專用培養(yǎng)基 (DMEM) , MCF7 [MCF-7] 細(xì)胞 , ZR-75-1 細(xì)胞
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RAMP2-AS1 inhibits CXCL11 expression to suppress malignant phenotype of breast cancer by recruiting DNMT1 and DNMT3B (2022-04-04)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2022.113139
影響因子 :3.7
引用產(chǎn)品: HCC1937 細(xì)胞 , MDA-MB-231 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MCF 10A 細(xì)胞
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Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer (2021-04-19)
期刊:Cell Death & Disease
DOI:10.1038/s41419-021-03684-x
影響因子 :9.0
引用產(chǎn)品: MDA-MB-231 細(xì)胞 , MDA-MB-468 細(xì)胞 , MDA-MB-453 細(xì)胞 , BT-549 細(xì)胞 , MCF 10A 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , BT-474 [BT474] 細(xì)胞
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CircFBXL5 promotes the 5-FU resistance of breast cancer via modulating miR-216b/HMGA2 axis (2021-07-19)
期刊:Cancer Cell International
DOI:10.1186/s12935-021-02088-3
影響因子 :5.8
引用產(chǎn)品: MCF 10A 細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-231 細(xì)胞 , DMEM/F12 培養(yǎng)基
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Circular RNA circ-ERBB2 Elevates the Warburg Effect and Facilitates Triple-Negative Breast Cancer Growth by the MicroRNA 136-5p/Pyruvate Dehydrogenase Kinase 4 Axis (2021-09-24)
期刊:MOLECULAR AND CELLULAR BIOLOGY
影響因子 :5.3
引用產(chǎn)品: BT-549 細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-231 細(xì)胞 , MCF 10A 細(xì)胞 , 特級(jí)胎牛血清 , MDA-MB-468-06 細(xì)胞 , Leibovitz's L-15 培養(yǎng)基 , RPMI-1640 培養(yǎng)基 , MCF 10A細(xì)胞專用培養(yǎng)基 , 青霉素-鏈霉素溶液(雙抗),100×
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circKLHL24 Blocks Breast Cancer Development by Regulating the miR-1204/ALX4 Network (2021-03-30)
期刊:CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
影響因子 :3.6
引用產(chǎn)品: BT-549 細(xì)胞 , MDA-MB-231 細(xì)胞 , HCC38 細(xì)胞 , SUM159PT 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF 10A 細(xì)胞
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Sericin inhibits MDA?MB?468 cell proliferation via the PI3K/Akt pathway in triple?negative breast cancer (2020-12-13)
期刊:Molecular Medicine Reports
影響因子 :3.4
引用產(chǎn)品: MDA-MB-468 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MCF 10A 細(xì)胞
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miR-29b-3p promotes progression of MDA-MB-231 triple-negative breast cancer cells through downregulating TRAF3 (2019-07-26)
期刊:Biological Research
影響因子 :6.7
引用產(chǎn)品: MDA-MB-231 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF 10A 細(xì)胞 , MCF 10A細(xì)胞專用培養(yǎng)基
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4-Amino-2-trifluoromethyl-phenyl retinate inhibits proliferation, invasion, and migration of breast cancer cells by independently regulating CRABP2 and FABP5 (2018-04-27)
期刊:Drug Design Development and Therapy
影響因子 :4.3
引用產(chǎn)品: MDA-MB-435 細(xì)胞 , MDA-MB-231 細(xì)胞 , MEM 培養(yǎng)基 , MDA-MB-453 細(xì)胞
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