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產(chǎn)品概述
名稱 | ZR-75-1 (人乳腺癌細(xì)胞) (STR鑒定正確) |
別稱 | ZR751; ZR75-1; ZR75_1 |
種屬 | 人 |
生長(zhǎng)特性 | 貼壁細(xì)胞 |
細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:2-1:3 |
推薦換液頻率 | 2-3次/周 |
背景描述 | ZR-75-1細(xì)胞產(chǎn)生高水平的黏液素MUC-1 mRNA,低水平的MUC-2 mRNA,但不表達(dá)MUC-3基因;ZR-75-1細(xì)胞表達(dá)雌激素受體。 |
年齡(性別) | 女性 |
組織來(lái)源 | 乳腺癌 |
細(xì)胞類型 | 腫瘤細(xì)胞 |
腫瘤類型 | 乳腺癌細(xì)胞 |
生物安全等級(jí) | BSL-1 |
倍增時(shí)間 | ~50-80 hours |
致瘤性 | Yes, forms tumors in nude mice. |
受體表達(dá)情況 | estrogen receptor, expressed |
基因表達(dá)情況 | mucin (apomucin, MUC-1, MUC-2) |
保藏機(jī)構(gòu) | ATCC; CRL-1500 ECACC; 87012601 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 10,11 D2S1338 16,25 D3S1358 15,16 D5S818 13 D7S820 10,11 D8S1179 11,13 D13S317 9 D16S539 11 D18S51 13,14 D19S433 13,14 D21S11 31 FGA 20,22 PentaD 14 PentaE 7,14 TH01 7,9.3 TPOX 8 vWA 16,18 D6S1043 12 D12S391 21 D2S441 11,15 -
STR鑒定圖
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參考文獻(xiàn)
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A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine (2025-02-10)
期刊:EMBO REPORTS
DOI:10.1038/s44319-025-00385-w
影響因子 :6.5
引用產(chǎn)品: 293FT 細(xì)胞 , JeKo-1 細(xì)胞 , Jurkat, Clone E6-1 細(xì)胞 , T-47D 細(xì)胞 , BT-549 細(xì)胞 , HCC1937 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , ZR-75-1 細(xì)胞 , BT-474 [BT474] 細(xì)胞 , MDA-MB-436 細(xì)胞 , RPMI-1640 培養(yǎng)基 , McCoy's 5A 培養(yǎng)基 , DMEM高糖 培養(yǎng)基
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SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer (2025-02-03)
期刊:NEOPLASIA
影響因子 :6.3
引用產(chǎn)品: ZR-75-1 細(xì)胞 , HCC1954 細(xì)胞 , MDA-MB-453 細(xì)胞 , 青霉素-鏈霉素溶液(雙抗),100×
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TMEM120B strengthens breast cancer cell stemness and accelerates chemotherapy resistance via β1-integrin/FAK-TAZ-mTOR signaling axis by binding to MYH9 (2024-03-19)
期刊:BREAST CANCER RESEARCH
DOI:10.1186/s13058-024-01802-z
影響因子 :7.4
引用產(chǎn)品: ZR-75-1 細(xì)胞 , MDA-MB-468 細(xì)胞
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TP53R175H mutation promotes breast cancer cell proliferation through CORO1A–P38 MAPK pathway regulation (2024-02-07)
期刊:BIOCHEMICAL PHARMACOLOGY
影響因子 :5.8
引用產(chǎn)品: ZR-75-1 細(xì)胞 , MCF 10A 細(xì)胞 , MCF 10A細(xì)胞專用培養(yǎng)基
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An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2 (2024-01-30)
期刊:Cancer Cell International
DOI:10.1186/s12935-024-03245-0
影響因子 :5.8
引用產(chǎn)品: MDA-MB-231/GFP 細(xì)胞 , MDA-MB-468 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , MCF 10A 細(xì)胞 , ZR-75-1 細(xì)胞
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Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling (2024-04-12)
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23724
影響因子 :4.6
引用產(chǎn)品: MCF 10A 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , ZR-75-1 細(xì)胞 , MDA-MB-231 細(xì)胞 , T-47D 細(xì)胞 , BT-549 細(xì)胞 , MDA-MB-468-06 細(xì)胞
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Prognostic and immune correlation of IDO1 promoter methylation in breast cancer (2024-11-13)
期刊:Scientific Reports
DOI:10.1038/s41598-024-79149-w
影響因子 :3.8
引用產(chǎn)品: DMEM高糖 培養(yǎng)基 , T-47D 細(xì)胞 , JIMT-1 細(xì)胞 , MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞 , MEM完全培養(yǎng)基(含10% FBS) , 特級(jí)胎牛血清 , A549 [A-549] 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , ZR-75-1 細(xì)胞 , 青霉素-鏈霉素溶液(雙抗),100× , RPMI-1640 培養(yǎng)基 , HCC1806 細(xì)胞
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Alleviating role of ketamine in breast cancer cell-induced osteoclastogenesis and tumor bone metastasis-induced bone cancer pain through an SRC/EGR1/CST6 axis (2024-12-18)
期刊:BMC CANCER
DOI:10.1186/s12885-024-13290-7
影響因子 :3.4
引用產(chǎn)品: MDA-MB-231 細(xì)胞 , ZR-75-1 細(xì)胞 , RAW 264.7 細(xì)胞
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A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer (2023-07-05)
期刊:Molecular Cancer
DOI:10.1186/s12943-023-01806-x
影響因子 :37.3
引用產(chǎn)品: MDA-MB-231 細(xì)胞 , MDA-MB-468 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , Hs 578T 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , T-47D 細(xì)胞 , ZR-75-1 細(xì)胞 , MCF 10A 細(xì)胞
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Scoparone inhibits breast cancer cell viability through the NF?κB signaling pathway (2023-05-17)
期刊:Experimental and Therapeutic Medicine
影響因子 :2.7
引用產(chǎn)品: MCF 10A 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MDA-MB-231 細(xì)胞 , ZR-75-1 細(xì)胞 , HCC1937 細(xì)胞 , 293 [HEK-293] 細(xì)胞
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CD24 May Serve as an Immunotherapy Target in Triple-Negative Breast Cancer by Regulating the Expression of PD-L1 (2023-12-31)
期刊:Breast Cancer-Targets and Therapy
影響因子 :2.6
引用產(chǎn)品: ZR-75-1 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , JIMT-1 細(xì)胞 , MDA-MB-468-06 細(xì)胞 , MDA-MB-231 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞
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Asiaticoside hampers epithelial–mesenchymal transition by promoting PPARG expression and suppressing P2RX7-mediated TGF-β/Smad signaling in triple-negative breast cancer (2022-11-28)
期刊:PHYTOTHERAPY RESEARCH
DOI:10.1002/ptr.7692
影響因子 :6.4
引用產(chǎn)品: 人乳腺上皮細(xì)胞 , MDA-MB-453 細(xì)胞 , MDA-MB-231細(xì)胞專用培養(yǎng)基 (DMEM) , MCF7 [MCF-7] 細(xì)胞 , ZR-75-1 細(xì)胞
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Heat shock protein 20 suppresses breast carcinogenesis by inhibiting the MAPK and AKT signaling pathways (2022-11-03)
期刊:Oncology Letters
影響因子 :3.1
引用產(chǎn)品: ZR-75-1 細(xì)胞
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Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader (2019-06-06)
期刊:Pharmacological Research
DOI:10.1016/j.phrs.2019.104294
影響因子 :9.3
引用產(chǎn)品: ZR-75-1 細(xì)胞
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