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產(chǎn)品概述
| 名稱 | SUM159PT (人乳腺癌細(xì)胞系) (STR鑒定正確) |
| 別稱 | SUM-159-PT; SUM-159PT; SUM 159PT; SUM-159; SUM 159; SUM159; 159 PT; 159PT |
| 種屬 | 人 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:8 |
| 推薦換液頻率 | 2-3次/周 |
| 年齡（性別） | 女性；71歲 |
| 組織來源 | 乳腺癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 乳腺癌細(xì)胞 |
| 生物安全等級 | BSL-1 |
STR鑒定
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STR位點信息
Amelogenin X CSF1PO 10,11 D2S1338 16,24 D3S1358 11,16 D5S818 11 D7S820 10 D8S1179 11,13 D13S317 12 D16S539 11 D18S51 12,14 D19S433 13.2,14 D21S11 28 FGA 21,22 PentaD 9,11 PentaE 17 TH01 6,7 TPOX 8,11 vWA 16 D6S1043 13,18 D12S391 17,22 D2S441 11,14 -
STR鑒定圖
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參考文獻(xiàn)
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L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer (2025-01-02)
期刊：Nature Communications
DOI：10.1038/s41467-024-55617-9
影響因子 ：14.7
引用產(chǎn)品： SUM159PT 細(xì)胞
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eNAMPT/Ac-STAT3/DIRAS2 Axis Promotes Development and Cancer Stemness in Triple-Negative Breast Cancer by Enhancing Cytokine Crosstalk Between Tumor-Associated Macrophages and Cancer Cells (2025-02-18)
期刊：International Journal of Biological Sciences
影響因子 ：8.2
引用產(chǎn)品： MDA-MB-231/GFP 細(xì)胞 , SUM159PT 細(xì)胞 , THP-1 細(xì)胞 , MCF 10A 細(xì)胞
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Multiomics analysis reveals the involvement of NET1 in tumour immune regulation and malignant progression (2025-01-02)
期刊：Scientific Reports
DOI：10.1038/s41598-024-83714-8
影響因子 ：3.8
引用產(chǎn)品： MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞 , BT-549 細(xì)胞
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Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer (2024-01-29)
期刊：Cell Reports Medicine
DOI：10.1016/j.xcrm.2024.101396
影響因子 ：11.7
引用產(chǎn)品： SUM159PT 細(xì)胞
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Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells (2024-05-30)
期刊：Cell Chemical Biology
DOI：10.1016/j.chembiol.2024.05.003
影響因子 ：6.6
引用產(chǎn)品： MEM（含NEAA） 培養(yǎng)基 , MCF7 [MCF-7] 細(xì)胞 , SUM159PT 細(xì)胞
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RERE-AS1 enhances the effect of CDK4/6 inhibitor Ribociclib and suppresses malignant phenotype in breast cancer via MEK/ERK pathway (2024-11-22)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05828-x
影響因子 ：6.1
引用產(chǎn)品： 293T [HEK-293T] 細(xì)胞 , T-47D 細(xì)胞 , Hs 578T 細(xì)胞 , MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞 , BT-549 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , MDA-MB-468-06 細(xì)胞 , BT-474 [BT474] 細(xì)胞
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Inhibition of the ATR-DNAPKcs-RB axis drives G1/S-phase transition and sensitizes triple-negative breast cancer (TNBC) to DNA holliday junctions (2024-05-22)
期刊：BIOCHEMICAL PHARMACOLOGY
影響因子 ：5.8
引用產(chǎn)品： SUM159PT 細(xì)胞
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Antiplatelet drug ticagrelor suppresses triple negative breast cancer metastasis by targeting PI3K (2024-07-03)
期刊：BIOCHEMICAL PHARMACOLOGY
影響因子 ：5.3
引用產(chǎn)品： 特級胎牛血清 , MDA-MB-157 細(xì)胞 , SUM159PT 細(xì)胞 , MDA-MB-435 細(xì)胞 , HCC1937 細(xì)胞 , MDA-MB-468-06 細(xì)胞 , MDA-MB-231 細(xì)胞
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SPOP negatively regulates mTORC1 activity by ubiquitinating Sec13 (2024-01-17)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111060
影響因子 ：4.4
引用產(chǎn)品： SUM159PT 細(xì)胞
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Prognostic and immune correlation of IDO1 promoter methylation in breast cancer (2024-11-13)
期刊：Scientific Reports
DOI：10.1038/s41598-024-79149-w
影響因子 ：3.8
引用產(chǎn)品： DMEM高糖 培養(yǎng)基 , T-47D 細(xì)胞 , JIMT-1 細(xì)胞 , MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞 , MEM完全培養(yǎng)基（含10% FBS） , 特級胎牛血清 , A549 [A-549] 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , ZR-75-1 細(xì)胞 , 青霉素-鏈霉素溶液（雙抗），100× , RPMI-1640 培養(yǎng)基 , HCC1806 細(xì)胞
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Identifying the mechanism of polysaccharopeptide against breast cancer based on network pharmacology and experimental verification (2024-06-13)
期刊：BMC CANCER
DOI：10.1186/s12885-024-12494-1
影響因子 ：3.4
引用產(chǎn)品： MCF7 [MCF-7] 細(xì)胞 , MCF 10A 細(xì)胞 , MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞
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EP300 promotes tumor stemness via epigenetic activation of CRISP3 leading to lobaplatin resistance in triple-negative breast cancer (2024-06-16)
期刊：Human Cell
DOI：10.1007/s13577-024-01091-w
影響因子 ：3.4
引用產(chǎn)品： RPMI-1640 培養(yǎng)基 , Leibovitz's L-15 培養(yǎng)基 , MDA-MB-453 細(xì)胞 , SUM159PT 細(xì)胞
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M2 macrophages promote PD-L1 expression in triple-negative breast cancer via secreting CXCL1 (2024-07-09)
期刊：PATHOLOGY RESEARCH AND PRACTICE
影響因子 ：2.9
引用產(chǎn)品： THP-1 細(xì)胞 , MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞
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USP36 stabilizes nucleolar Snail1 to promote ribosome biogenesis and cancer cell survival upon ribotoxic stress (2023-10-13)
期刊：Nature Communications
DOI：10.1038/s41467-023-42257-8
影響因子 ：16.6
引用產(chǎn)品： SUM159PT 細(xì)胞 , NCI-H1299 細(xì)胞
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Natural Compounds, Optimal Combination of Brusatol and Polydatin Promote Anti-Tumor Effect in Breast Cancer by Targeting Nrf2 Signaling Pathway (2023-05-05)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.6
引用產(chǎn)品： MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞
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Development of Piperazine- and Oxazine-Linked Pyrimidines as p65 Subunit Binders of NF–κB in Human Breast Cancer Cells (2023-10-06)
期刊：Biomedicines
DOI：10.3390/biomedicines11102716
影響因子 ：4.7
引用產(chǎn)品： MCF7 [MCF-7] 細(xì)胞 , MDA-MB-231 細(xì)胞 , BT-549 細(xì)胞 , SUM159PT 細(xì)胞
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Retraction of “Label-Free Isolation of Low-Adhesion Cells with Stem Properties for Cancer Stem Cell-Specific Drug Evaluation” (2022-09-19)
期刊：ANALYTICAL CHEMISTRY
DOI：10.1021/acs.analchem.2c00444
影響因子 ：8.0
引用產(chǎn)品： MCF7 [MCF-7] 細(xì)胞 , MDA-MB-231 細(xì)胞 , SUM159PT 細(xì)胞 , B16 細(xì)胞 , MDA-MB-435 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , McCoy's 5A 培養(yǎng)基
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Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer (2022-09-02)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.2c01058
影響因子 ：8.0
引用產(chǎn)品： MDA-MB-231 細(xì)胞 , 青霉素-鏈霉素溶液 (雙抗)，100× , SUM159PT 細(xì)胞
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Quercus acutissima Carruth. root extract triggers apoptosis, autophagy and inhibits cell viability in breast cancer cells (2022-01-29)
期刊： journal of ethnopharmacology
影響因子 ：5.4
引用產(chǎn)品： SUM159PT 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞
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ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer (2021-04-30)
期刊：Journal of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-021-01932-8
影響因子 ：11.3
引用產(chǎn)品： SUM159PT 細(xì)胞
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circKLHL24 Blocks Breast Cancer Development by Regulating the miR-1204/ALX4 Network (2021-03-30)
期刊：CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
影響因子 ：3.6
引用產(chǎn)品： BT-549 細(xì)胞 , MDA-MB-231 細(xì)胞 , HCC38 細(xì)胞 , SUM159PT 細(xì)胞 , MDA-MB-453 細(xì)胞 , MCF 10A 細(xì)胞
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