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HEC-1-A (人子宮內(nèi)膜腺癌細胞) (STR鑒定正確)
貨號：CL-0099
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價格： ￥1400
生長培養(yǎng)基：McCoy’s 5A＋10% FBS＋1% P/S
產(chǎn)品概述
| 名稱 | HEC-1-A (人子宮內(nèi)膜腺癌細胞) (STR鑒定正確) |
| 別稱 | Hec-1-A; HEC-1A; HEC1-A; HEC1A; Hec1A |
| 種屬 | 人 |
| 生長特性 | 貼壁細胞 |
| 細胞形態(tài) | 上皮細胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認） |
生長培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
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| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | HEC-1-A細胞及其亞株HEC-1-B細胞是H·Kuramoto及其同事于1968年從一位ⅠA期子宮內(nèi)膜癌患者身上分離得到的。PAF可以誘導，HEC-1-A細胞c-fos的表達。 |
| 年齡（性別） | 女性；71歲 |
| 組織來源 | 腺癌；子宮；子宮內(nèi)膜炎 |
| 細胞類型 | 腫瘤細胞 |
| 腫瘤類型 | 子宮內(nèi)膜腺癌 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~27-36 hours |
| 致瘤性 | Yes, in nude mice (The cells form moderately well differentiated adenocarcinomas consistent with endometrial carcinoma (grade II)).Yes, in the cheek pouch of cortisone treated hamsters (The cells form typical papillary adenomas). |
| 受體表達情況 | platelet activating factor (PAF) |
| 抗原表達情況 | Blood Type B; Rh+ |
| 基因表達情況 | c-fos+ |
| 保藏機構(gòu) | ATCC; HTB-112 BCRC; 60552 JCRB; JCRB1117 JCRB; NIHS0388 |
STR鑒定
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STR位點信息
Amelogenin X CSF1PO 10,12 D2S1338 18,19 D3S1358 15 D5S818 11,15 D7S820 9,11 D8S1179 13,14 D13S317 11 D16S539 12 D18S51 16,21 D19S433 13 D21S11 30,31 FGA 21,22 PentaD 9,12,13 PentaE 11 TH01 6,7 TPOX 8,11 vWA 18,19 D6S1043 12,18 D12S391 19 D2S441 11,13 -
STR鑒定圖
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參考文獻
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Multimodal near-infrared molecular imaging of ex vivo endometrial carcinoma via CD47-based targeted tracer (2025-02-04)
期刊：Bioengineering & Translational Medicine
影響因子 ：6.1
引用產(chǎn)品： KLE 細胞 , HEC-1-A 細胞
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Characterization of G2/M checkpoint classifier for personalized treatment in uterine corpus endometrial carcinoma (2025-02-07)
期刊：Cancer Cell International
DOI：10.1186/s12935-025-03667-4
影響因子 ：5.3
引用產(chǎn)品： HEC-1-A 細胞
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NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT (2025-01-01)
期刊：Journal of Cancer
影響因子 ：3.3
引用產(chǎn)品： HEC-1-A 細胞 , HEC-1-B 細胞 , Ishikawa 細胞
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Integrated analysis and experiments uncover the function of disulfidptosis in predicting immunotherapy effectiveness and delineating immune landscapes in uterine corpus endometrial carcinoma (2024-10-09)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1454730
影響因子 ：5.7
引用產(chǎn)品： HEC-1-A細胞專用培養(yǎng)基 , HEC-1-A 細胞
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ERP29 regulates the proliferation of endometrial carcinoma via M6A modification (2024-08-12)
期刊：LIFE SCIENCES
影響因子 ：5.2
引用產(chǎn)品： HEC-1-A 細胞 , Ishikawa 細胞 , DMEM高糖 培養(yǎng)基
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Long noncoding RNA VPS9D1-AS1 promotes the progression of endometrial cancer via regulation of the miR-187-3p/S100A4 axis (2024-07-02)
期刊：ENVIRONMENTAL TOXICOLOGY
影響因子 ：4.4
引用產(chǎn)品： 人子宮內(nèi)膜上皮細胞 , HEC-1-A 細胞 , KLE 細胞 , Ishikawa 細胞 , RL95-2 細胞
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SIM2: Its Prognostic Significance and Oncogenic Role in Endometrial Carcinoma (2024-01-26)
期刊：OncoTargets and Therapy
影響因子 ：4.0
引用產(chǎn)品： Ishikawa 細胞 , HEC-1-A 細胞
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Lactamase β reprograms lipid metabolism to inhibit the progression of endometrial cancer through attenuating MDM2-mediated p53 ubiquitination and degradation (2024-12-31)
期刊：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影響因子 ：3.8
引用產(chǎn)品： RL95-2 細胞 , HEC-1-A 細胞 , Ishikawa 細胞 , AN3 CA 細胞 , KLE 細胞
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Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer (2024-04-24)
期刊：CYTOTECHNOLOGY
DOI：10.1007/s10616-024-00629-y
影響因子 ：2.2
引用產(chǎn)品： HEC-1-A 細胞 , KLE 細胞
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SOX4 inhibits ferroptosis and promotes proliferation of endometrial cancer cells via the p53/SLC7A11 signaling (2024-09-24)
期刊：JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
影響因子 ：1.6
引用產(chǎn)品： HEC-1-A 細胞 , RL95-2 細胞 , AN3 CA 細胞 , Ishikawa 細胞
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Construction of the novel immune risk scoring system related to CD8+ T cells in uterine corpus endometrial carcinoma (2023-06-22)
期刊：Cancer Cell International
DOI：10.1186/s12935-023-02966-y
影響因子 ：5.8
引用產(chǎn)品： HEC-1-A 細胞 , Ishikawa 細胞
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Comprehensive analysis and experimental validation reveal elevated CLCN4 is a promising biomarker in endometrial cancer (2023-09-05)
期刊：Aging-US
影響因子 ：5.2
引用產(chǎn)品： HEC-1-A 細胞
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Mechanism of action of icaritin on uterine corpus endometrial carcinoma based on network pharmacology and experimental evaluation (2023-07-19)
期刊：Frontiers in Oncology
影響因子 ：4.7
引用產(chǎn)品： HEC-1-A 細胞
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Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma (2023-03-11)
期刊：Scientific Reports
DOI：10.1038/s41598-023-31325-0
影響因子 ：4.6
引用產(chǎn)品： HEC-1-A 細胞
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Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer (2023-08-28)
期刊：Journal of Cancer
影響因子 ：3.9
引用產(chǎn)品： HEC-1-A 細胞 , HEC-1-B 細胞
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Ferroptosis-related lncRNA model based on CFAP58-DT for predicting prognosis and immunocytes infiltration in endometrial cancer (2023-02-10)
期刊：Annals of Translational Medicine
影響因子 ：3.6
引用產(chǎn)品： HEC-1-A 細胞 , Ishikawa 細胞 , 特級胎牛血清 , 增強型細胞活力檢測試劑盒 (CCK-8)
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ZAP70 interaction with 13 mRNAs as a potential immunotherapeutic target for endometrial cancer (2023-04-06)
期刊：Oncology Letters
影響因子 ：2.9
引用產(chǎn)品： HEC-1-A 細胞 , Ishikawa 細胞 , 特級胎牛血清
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IGFBP?rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway (2023-03-03)
期刊：Experimental and Therapeutic Medicine
影響因子 ：2.7
引用產(chǎn)品： Ishikawa 細胞 , HEC-1-A 細胞 , RL95-2 細胞 , HEC-1-B 細胞 , AN3 CA 細胞 , THP-1 細胞
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Friend leukemia integration 1 overexpression decreases endometrial receptivity and induces embryo implantation failure by promoting PART1 transcription in the endometrial epithelial cells (2023-09-26)
期刊：PeerJ
影響因子 ：2.7
引用產(chǎn)品： HEC-1-A 細胞 , Ishikawa 細胞 , RL95-2 細胞 , BeWo 細胞
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LINC01857 Exacerbates the Malignant Behaviors of Endometrial Carcinoma Cells by Sponging miR-19b-3p and Recruiting ELAVL1 to Upregulate MYCN (2023-03-28)
期刊：GYNECOLOGIC AND OBSTETRIC INVESTIGATION
影響因子 ：2.1
引用產(chǎn)品： HEC-1-A 細胞 , HEC-1-B 細胞 , Ishikawa 細胞 , RL95-2 細胞
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Effects of RFRP?3 on an ovariectomized estrogen?primed rat model and HEC?1A human endometrial carcinoma cells (2022-12-23)
期刊：Experimental and Therapeutic Medicine
影響因子 ：2.8
引用產(chǎn)品： HEC-1-A 細胞
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Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: A clue to enhance endometrial receptivity in recurrent implantation failure (2022-12-22)
期刊：EUROPEAN JOURNAL OF HISTOCHEMISTRY
影響因子 ：2.0
引用產(chǎn)品： Ishikawa 細胞 , HEC-1-A 細胞
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CMBs carrying PTX and CRISPR/Cas9 targeting C?erbB?2 plasmids interfere with endometrial cancer cells (2021-09-30)
期刊：Molecular Medicine Reports
影響因子 ：3.4
引用產(chǎn)品： HEC-1-A 細胞
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Exosomal-lncRNA DLEU1 Accelerates the Proliferation, Migration, and Invasion of Endometrial Carcinoma Cells by Regulating microRNA-E2F3 (2020-08-25)
期刊：OncoTargets and Therapy
影響因子 ：4.0
引用產(chǎn)品： KLE 細胞 , Ishikawa 細胞 , HEC-1-A 細胞 , RL95-2 細胞
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Silencing of Long Non-Coding RNA LINC01106 Suppresses the Proliferation, Migration and Invasion of Endometrial Cancer Cells Through Regulating the miR-449a/MET Axis (2020-09-29)
期刊：OncoTargets and Therapy
影響因子 ：4.0
引用產(chǎn)品： KLE 細胞 , Ishikawa 細胞 , HEC-1-A 細胞
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