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產(chǎn)品概述
| 名稱 | OS-RC-2 (人腎癌細(xì)胞) (STR鑒定正確) |
| 別稱 | RC-2 |
| 種屬 | 人 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | OS-RC-2細(xì)胞來源于日本人的腎臟腫瘤細(xì)胞；OS-RC-2細(xì)胞移植到裸鼠可成瘤。 |
| 年齡（性別） | 男性；52歲 |
| 組織來源 | 腎 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 腎癌細(xì)胞 |
| 倍增時間 | ~60-72 hours |
STR鑒定
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STR位點信息
Amelogenin X,Y CSF1PO 12,13 D2S1338 20 D3S1358 17 D5S818 11,12 D7S820 10,11 D8S1179 14 D13S317 8,12 D16S539 11 D18S51 14 D19S433 13,14 D21S11 31.2 FGA 24 PentaD 11 PentaE 11,17 TH01 6 TPOX 8,11 vWA 16 D6S1043 12 D12S391 20,23 D2S441 11 -
STR鑒定圖
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參考文獻(xiàn)
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HIF-2α/LPCAT1 orchestrates the reprogramming of lipid metabolism in ccRCC by modulating the FBXW7-mediated ubiquitination of ACLY (2025-01-01)
期刊：International Journal of Biological Sciences
影響因子 ：8.2
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , A-498 細(xì)胞 , ACHN 細(xì)胞 , Caki-1 細(xì)胞 , HK-2 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Hypoxia-triggered ERRα acetylation enhanced its oncogenic role and promoted progression of renal cell carcinoma by coordinating autophagosome-lysosome fusion (2025-01-16)
期刊：Cell Death & Disease
DOI：10.1038/s41419-025-07345-1
影響因子 ：8.1
引用產(chǎn)品： HK-2 細(xì)胞 , ACHN 細(xì)胞 , A-498 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Machine learning-derived prognostic signature integrating programmed cell death and mitochondrial function in renal clear cell carcinoma: identification of PIF1 as a novel target (2025-02-25)
期刊：CANCER IMMUNOLOGY IMMUNOTHERAPY
DOI：10.1007/s00262-025-03967-8
影響因子 ：4.6
引用產(chǎn)品： Caki-1 細(xì)胞 , OS-RC-2 細(xì)胞 , A-498 細(xì)胞
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PUS1 facilitates cell migration in clear cell renal cell carcinoma through the promotion of mRNA pseudouridylation and the stabilization of the SMOX gene (2025-02-22)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2025.111700
影響因子 ：4.4
引用產(chǎn)品： HK-2 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , A-498 細(xì)胞 , OS-RC-2 細(xì)胞
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Atractylenolide I inhibits angiogenesis and reverses sunitinib resistance in clear cell renal cell carcinoma through ATP6V0D2-mediated autophagic degradation of EPAS1/HIF2α (2024-11-04)
期刊：Autophagy
DOI：10.1080/15548627.2024.2421699
影響因子 ：14.6
引用產(chǎn)品： OS-RC-2 細(xì)胞
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USP7 depletion potentiates HIF2α degradation and inhibits clear cell renal cell carcinoma progression (2024-10-15)
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-07136-0
影響因子 ：8.1
引用產(chǎn)品： Caki-2 細(xì)胞 , A-498 細(xì)胞 , OS-RC-2 細(xì)胞 , 786-O [786-0] 細(xì)胞
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A multifunctional antibody fusion protein 57103 targeting CD24, IL-4R, and αvβ3 for treating cancer and regulating the tumor microenvironment (2024-05-17)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.116714
影響因子 ：6.9
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , A-498 細(xì)胞 , OS-RC-2 細(xì)胞 , Caki-2 細(xì)胞
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TRIM26 inhibits clear cell renal cell carcinoma progression through destabilizing ETK and thus inactivation of AKT/mTOR signaling (2024-05-21)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05273-w
影響因子 ：6.1
引用產(chǎn)品： Caki-1 細(xì)胞 , OS-RC-2 細(xì)胞
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Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma (2024-02-08)
期刊：Aging-US
影響因子 ：5.2
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , A-498 細(xì)胞 , ACHN 細(xì)胞 , HK-2 細(xì)胞
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Bioinformatics analysis and experimental verification of the cancer-promoting effect of DHODH in clear cell renal cell carcinoma (2024-05-25)
期刊：Scientific Reports
DOI：10.1038/s41598-024-62738-0
影響因子 ：4.6
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , RPMI-1640 培養(yǎng)基 , OS-RC-2 細(xì)胞
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Improved Immunotherapy Outcomes via Cuproptosis Upregulation of HLA-DRA Expression: Promoting the Aggregation of CD4+ and CD8+T Lymphocytes in Clear Cell Renal Cell Carcinoma (2024-05-24)
期刊：Pharmaceuticals
影響因子 ：4.3
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , A-498 細(xì)胞 , HK-2 細(xì)胞 , Renca [RenCa] 細(xì)胞
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SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment (2024-05-16)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2024.116975
影響因子 ：3.8
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , SW839 細(xì)胞 , A-498 細(xì)胞 , HK-2 細(xì)胞 , OS-RC-2 細(xì)胞 , THP-1 細(xì)胞
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Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC (2024-03-21)
期刊：GENE
DOI：10.1016/j.gene.2024.148403
影響因子 ：3.5
引用產(chǎn)品： HK-2 細(xì)胞 , ACHN 細(xì)胞 , A-498 細(xì)胞 , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , Caki-1 細(xì)胞 , RPMI-1640 培養(yǎng)基 , MEM 培養(yǎng)基
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AGBL2 promotes renal cell carcinoma cells proliferation and migration via α-tubulin detyrosination (2024-09-04)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e37086
影響因子 ：3.4
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Exploring necrosis-associated mitochondrial gene signatures: revealing their role in prognosis and immunotherapy of renal clear cell carcinoma (2024-07-18)
期刊：CLINICAL AND EXPERIMENTAL MEDICINE
DOI：10.1007/s10238-024-01426-9
影響因子 ：3.2
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , ACHN 細(xì)胞 , Caki-1 細(xì)胞 , HK-2 細(xì)胞
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ETS homologous factor, controlled by lysine-specific demethylase 5B, suppresses clear cell renal cell carcinoma by inducing Filamin-B (2024-06-14)
期刊：GENE
DOI：10.1016/j.gene.2024.148702
影響因子 ：2.6
引用產(chǎn)品： OS-RC-2 細(xì)胞 , Caki-1 細(xì)胞 , HK-2 細(xì)胞 , THP-1 細(xì)胞
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Comprehensive Pan-Cancer Analysis of Connexin 43 as a Potential Biomarker and Therapeutic Target in Human Kidney Renal Clear Cell Carcinoma (KIRC) (2024-05-08)
期刊：Medicina-Lithuania
影響因子 ：2.6
引用產(chǎn)品： ACHN 細(xì)胞 , OS-RC-2 細(xì)胞 , HK-2 細(xì)胞 , 786-O [786-0] 細(xì)胞
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METTL3 and IGF2BP1-mediated m6A modification of ZHX2 promotes tumor property of renal cell carcinoma (2024-08-19)
期刊：KIDNEY & BLOOD PRESSURE RESEARCH
影響因子 ：2.3
引用產(chǎn)品： RPMI-1640 完全培養(yǎng)基（含10% FBS） , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , HK-2 細(xì)胞 , 特級胎牛血清 , MEM（含NEAA） 培養(yǎng)基 , ACHN 細(xì)胞
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Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis (2024-05-11)
期刊：Discover Oncology
DOI：10.1007/s12672-024-01018-9
影響因子 ：2.2
引用產(chǎn)品： A-498 細(xì)胞 , Caki-2 細(xì)胞 , Caki-1 細(xì)胞 , 769-P 細(xì)胞 , 293 [HEK-293] 細(xì)胞 , OS-RC-2 細(xì)胞 , 786-O [786-0] 細(xì)胞
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Integrative bioinformatics and in vitro exploration of EVI2A expression: unraveling its immunological and prognostic implications in kidney renal clear cell carcinoma (2024-10-16)
期刊：ONCOLOGY RESEARCH
影響因子 ：2.0
引用產(chǎn)品： Caki-1 細(xì)胞 , OS-RC-2 細(xì)胞 , ACHN 細(xì)胞 , HK-2 細(xì)胞 , 786-O [786-0] 細(xì)胞
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Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination (2023-11-01)
期刊：ONCOGENE
DOI：10.1038/s41388-023-02879-0
影響因子 ：8.0
引用產(chǎn)品： A549 [A-549] 細(xì)胞 , NCI-H1299 細(xì)胞 , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , BEAS-2B 細(xì)胞 , McCoy's 5A 培養(yǎng)基
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HOXD8 suppresses renal cell carcinoma growth by upregulating SHMT1 expression (2023-09-26)
期刊：CANCER SCIENCE
影響因子 ：5.7
引用產(chǎn)品： OS-RC-2 細(xì)胞 , ACHN 細(xì)胞
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Root extract of Hemsleya amabilis Diels suppresses renal cell carcinoma cell growth through inducing apoptosis and G2/M phase arrest via PI3K/AKT signaling pathway activation (2023-08-07)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影響因子 ：5.4
引用產(chǎn)品： McCoy's 5A完全培養(yǎng)基 (含10%FBS） , MEM完全培養(yǎng)基 (含NEAA、10%FBS） , OS-RC-2 細(xì)胞 , ACHN 細(xì)胞
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Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1 (2023-05-29)
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-023-04877-x
影響因子 ：3.6
引用產(chǎn)品： HK-2 細(xì)胞 , Caki-1 細(xì)胞 , OS-RC-2 細(xì)胞
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Construction and Validation of a Novel Cuproptosis-Related Seven-lncRNA Signature to Predict the Outcomes, Immunotherapeutic Responses, and Targeted Therapy in Patients with Clear Cell Renal Cell Carcinoma (2023-01-25)
期刊：DISEASE MARKERS
影響因子 ：3.5
引用產(chǎn)品： A-498 細(xì)胞 , OS-RC-2 細(xì)胞
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway (2023-01-02)
期刊：MEDICAL ONCOLOGY
DOI：10.1007/s12032-022-01926-2
影響因子 ：3.4
引用產(chǎn)品： OS-RC-2 細(xì)胞 , 786-O [786-0] 細(xì)胞 , ACHN 細(xì)胞 , 769-P 細(xì)胞 , Caki-1 細(xì)胞
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Downregulation of NEBL promotes migration and invasion of clear cell renal cell carcinoma by inducing epithelial-mesenchymal transition (2023-12-29)
期刊：PATHOLOGY RESEARCH AND PRACTICE
影響因子 ：2.8
引用產(chǎn)品： 293T [HEK-293T] 細(xì)胞 , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞
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Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma (2022-09-30)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2022.1021935
影響因子 ：8.8
引用產(chǎn)品： ACHN 細(xì)胞 , HK-2 細(xì)胞 , Caki-2 細(xì)胞 , A-498 細(xì)胞 , Caki-1 細(xì)胞 , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , 769-P 細(xì)胞
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Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma (2022-01-14)
期刊：Faseb Journal
影響因子 ：4.8
引用產(chǎn)品： OS-RC-2 細(xì)胞 , Caki-1 細(xì)胞
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression (2022-11-30)
期刊：TRANSPLANT IMMUNOLOGY
DOI：10.1016/j.trim.2022.101764
影響因子 ：2.0
引用產(chǎn)品： HK-2 細(xì)胞 , OS-RC-2 細(xì)胞 , ACHN 細(xì)胞 , 786-O [786-0] 細(xì)胞
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