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產(chǎn)品概述
| 名稱 | 769-P (人腎細(xì)胞腺癌細(xì)胞) (STR鑒定正確) |
| 別稱 | 769P; 769-p |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:8 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | 769-P細(xì)胞來(lái)源于原發(fā)性透明細(xì)胞腺癌；769-P細(xì)胞呈邊界不清楚的球形、高核質(zhì)比、有微絨毛和橋粒；769-P細(xì)胞可以在軟瓊脂中生長(zhǎng)。 |
| 年齡（性別） | 女性；63歲 |
| 組織來(lái)源 | 器官：腎；疾?。耗I透明細(xì)胞腺癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 腎癌細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~35 hours |
| 致瘤性 | Yes, forms colonies in soft agar.Yes, forms tumors in immunosuppressed hamsters.Yes, forms tumors in nude mice. |
| 保藏機(jī)構(gòu) | ATCC; CRL-1933 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 11,12 D2S1338 18 D3S1358 16 D5S818 12 D7S820 10,11 D8S1179 12,16 D13S317 10,14 D16S539 9,13 D18S51 14,17 D19S433 14,15 D21S11 28,30 FGA 20,22 PentaD 12,16 PentaE 7,18 TH01 6,9.3 TPOX 8,11 vWA 18 D6S1043 11,14 D12S391 18 D2S441 11,14 -
STR鑒定圖
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參考文獻(xiàn)
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Hypoxia-triggered ERRα acetylation enhanced its oncogenic role and promoted progression of renal cell carcinoma by coordinating autophagosome-lysosome fusion (2025-01-16)
期刊：Cell Death & Disease
DOI：10.1038/s41419-025-07345-1
影響因子 ：8.1
引用產(chǎn)品： HK-2 細(xì)胞 , ACHN 細(xì)胞 , A-498 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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PUS1 facilitates cell migration in clear cell renal cell carcinoma through the promotion of mRNA pseudouridylation and the stabilization of the SMOX gene (2025-02-22)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2025.111700
影響因子 ：4.4
引用產(chǎn)品： HK-2 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , A-498 細(xì)胞 , OS-RC-2 細(xì)胞
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TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3 (2024-05-22)
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-06741-3
影響因子 ：9.0
引用產(chǎn)品： DMEM高糖 培養(yǎng)基 , McCoy's 5A 培養(yǎng)基 , MEM 培養(yǎng)基 , ACHN 細(xì)胞 , Caki-2 細(xì)胞 , RPMI-1640 培養(yǎng)基 , Caki-1 細(xì)胞 , 769-P 細(xì)胞
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Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells (2024-03-30)
期刊：APOPTOSIS
DOI：10.1007/s10495-024-01953-6
影響因子 ：7.2
引用產(chǎn)品： HK-2 細(xì)胞 , Caki-1 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , SW839 細(xì)胞
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CLIP170 enhancing FOSL1 expression via attenuating ubiquitin-mediated degradation of β-catenin drives renal cell carcinoma progression (2024-11-28)
期刊：CELLULAR AND MOLECULAR LIFE SCIENCES
DOI：10.1007/s00018-024-05504-9
影響因子 ：6.2
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , Caki-1 細(xì)胞 , 769-P 細(xì)胞 , HK-2 細(xì)胞 , ACHN 細(xì)胞
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Integrated Analysis of Single-Cell and Bulk RNA Sequencing Reveals HSD3B7 as a Prognostic Biomarker and Potential Therapeutic Target in ccRCC (2024-12-01)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：4.9
引用產(chǎn)品： A-498 細(xì)胞 , ACHN 細(xì)胞 , 769-P 細(xì)胞 , HK-2 細(xì)胞 , 特級(jí)胎牛血清
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Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma (2024-08-10)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112737
影響因子 ：4.8
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞
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Decoding Sunitinib Resistance in ccRCC: Metabolic reprogramming induced ABAT and GABAergic system shifts (2024-06-28)
期刊：iScience
DOI：10.1016/j.isci.2024.110415
影響因子 ：4.6
引用產(chǎn)品： HUV-EC-C [HUVEC] 細(xì)胞 , STR鑒定 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞
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Low ACADM expression predicts poor prognosis and suppressive tumor microenvironment in clear cell renal cell carcinoma (2024-04-25)
期刊：Scientific Reports
DOI：10.1038/s41598-024-59746-5
影響因子 ：4.6
引用產(chǎn)品： RPMI-1640 培養(yǎng)基 , 786-O [786-0] 細(xì)胞 , ACHN 細(xì)胞 , 769-P 細(xì)胞 , HK-2 細(xì)胞 , Caki-1 細(xì)胞 , McCoy's 5A 培養(yǎng)基 , MEM（含NEAA） 培養(yǎng)基
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LINC00645 inhibits renal cell carcinoma progression by interacting with HNRNPA2B1 to regulate the ROCK1 mRNA stability (2024-02-01)
期刊：GENE
DOI：10.1016/j.gene.2024.148232
影響因子 ：3.5
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞 , ACHN 細(xì)胞
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ZBP1 as a prognostic biomarker correlated with cell proliferation in clear cell renal cell carcinoma (2024-10-10)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e39267
影響因子 ：3.4
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , A-498 細(xì)胞 , HK-2 細(xì)胞 , ACHN 細(xì)胞 , 769-P 細(xì)胞
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Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma (2024-11-29)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2024.117181
影響因子 ：3.3
引用產(chǎn)品： Caki-1 細(xì)胞 , 786-O [786-0] 細(xì)胞 , Caki-2 細(xì)胞 , HK-2 細(xì)胞 , 769-P 細(xì)胞
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A novel cancer-associated fibroblast signature for kidney renal clear cell carcinoma via integrated analysis of single-cell and bulk RNA-sequencing (2024-07-26)
期刊：Discover Oncology
DOI：10.1007/s12672-024-01175-x
影響因子 ：2.8
引用產(chǎn)品： 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞
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Comprehensive analysis of signaling lymphocyte activation molecule family as a prognostic biomarker and correlation with immune infiltration in clear cell renal cell carcinoma (2024-06-03)
期刊：Oncology Letters
影響因子 ：2.5
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞
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PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway (2024-06-27)
期刊：PeerJ
影響因子 ：2.3
引用產(chǎn)品： Caki-1 細(xì)胞 , ACHN 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , 293 [HEK-293] 細(xì)胞
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Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis (2024-05-11)
期刊：Discover Oncology
DOI：10.1007/s12672-024-01018-9
影響因子 ：2.2
引用產(chǎn)品： A-498 細(xì)胞 , Caki-2 細(xì)胞 , Caki-1 細(xì)胞 , 769-P 細(xì)胞 , 293 [HEK-293] 細(xì)胞 , OS-RC-2 細(xì)胞 , 786-O [786-0] 細(xì)胞
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Exploring Novel Genome Instability-associated lncRNAs and their Potential Function in Pan-Renal Cell Carcinoma (2024-08-01)
期刊：COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
DOI：10.2174/0113862073258779231020052115
影響因子 ：1.6
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞
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CircSCNN1A inhibits the proliferation, migration and invasion of renal cell carcinoma cells by decreasing CLDN8 expression through miR-590-5p (2024-05-19)
期刊：GENESIS
影響因子 ：1.5
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , McCoy's 5A 培養(yǎng)基 , DMEM高糖 培養(yǎng)基 , A-498 細(xì)胞 , HK-2 細(xì)胞 , RPMI-1640 培養(yǎng)基 , 769-P 細(xì)胞 , Caki-1 細(xì)胞
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The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma (2023-05-12)
期刊：CELL DEATH AND DIFFERENTIATION
DOI：10.1038/s41418-023-01176-3
影響因子 ：12.4
引用產(chǎn)品： 769-P 細(xì)胞
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma (2023-03-15)
期刊：American Journal of Cancer Research
DOI：PMID:37034217
影響因子 ：5.3
引用產(chǎn)品： ACHN 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , MEM 培養(yǎng)基 , RPMI-1640 培養(yǎng)基
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Netrin Family Genes as Prognostic Markers and Therapeutic Targets for Clear Cell Renal Cell Carcinoma: Netrin-4 Acts through the Wnt/β-Catenin Signaling Pathway (2023-05-18)
期刊：Cancers
影響因子 ：5.2
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞
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Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function (2023-07-06)
期刊：Frontiers in Oncology
影響因子 ：4.7
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞 , HK-2 細(xì)胞
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The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma (2023-08-29)
期刊：Human Cell
DOI：10.1007/s13577-023-00973-9
影響因子 ：4.3
引用產(chǎn)品： HK-2 細(xì)胞 , 769-P 細(xì)胞 , McCoy's 5A 培養(yǎng)基
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ROCK2-RNA interaction map reveals multiple biological mechanisms underlying tumor progression in renal cell carcinoma (2023-07-07)
期刊：Human Cell
DOI：10.1007/s13577-023-00947-x
影響因子 ：4.3
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞 , Annexin V-FITC/ PI熒光雙染細(xì)胞凋亡檢測(cè)試劑盒
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway (2023-01-02)
期刊：MEDICAL ONCOLOGY
DOI：10.1007/s12032-022-01926-2
影響因子 ：3.4
引用產(chǎn)品： OS-RC-2 細(xì)胞 , 786-O [786-0] 細(xì)胞 , ACHN 細(xì)胞 , 769-P 細(xì)胞 , Caki-1 細(xì)胞
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A Novel Tumor Mutation Burden Related lncRNA Signature Identified Prognosis and Tumor Immune Microenvironment Features in Clear Cell Renal Cell Carcinoma (2023-07-01)
期刊：COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
DOI：10.2174/1386207325666220926123923
影響因子 ：1.8
引用產(chǎn)品： HK-2 細(xì)胞 , 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞 , ACHN 細(xì)胞 , Ham's F-12K 培養(yǎng)基
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Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma (2022-09-30)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2022.1021935
影響因子 ：8.8
引用產(chǎn)品： ACHN 細(xì)胞 , HK-2 細(xì)胞 , Caki-2 細(xì)胞 , A-498 細(xì)胞 , Caki-1 細(xì)胞 , 786-O [786-0] 細(xì)胞 , OS-RC-2 細(xì)胞 , 769-P 細(xì)胞
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Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis (2022-12-25)
期刊：Cancers
影響因子 ：6.6
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , ACHN 細(xì)胞 , Caki-1 細(xì)胞 , 769-P 細(xì)胞 , HK-2 細(xì)胞
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Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma (2022-02-16)
期刊：Journal of Inflammation Research
影響因子 ：4.5
引用產(chǎn)品： Caki-1 細(xì)胞 , 769-P 細(xì)胞 , 786-O [786-0] 細(xì)胞 , ACHN 細(xì)胞 , HK-2 細(xì)胞
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Upregulation of Metallothionein 1?G (MT1G) Negatively Regulates Ferroptosis in Clear Cell Renal Cell Carcinoma by Reducing Glutathione Consumption (2022-09-27)
期刊：Journal of Oncology
影響因子 ：4.5
引用產(chǎn)品： Caki-1 細(xì)胞 , 769-P 細(xì)胞
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis (2022-09-01)
期刊：Translational Andrology and Urology
影響因子 ：2.5
引用產(chǎn)品： A-498 細(xì)胞 , ACHN 細(xì)胞 , SN12C 細(xì)胞 , 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞
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Deubiquitylation and stabilization of ARMC5 by ubiquitin-specific processing protease 7 (USP7) are critical for RCC proliferation (2021-02-05)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 ：5.3
引用產(chǎn)品： 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞 , A-498 細(xì)胞 , ACHN 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT (2020-03-04)
期刊：Journal of Cancer
影響因子 ：3.9
引用產(chǎn)品： 769-P 細(xì)胞 , ACHN 細(xì)胞
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LncRNA-LET inhibits cell growth of clear cell renal cell carcinoma by regulating miR-373-3p (2019-11-21)
期刊：Cancer Cell International
影響因子 ：5.8
引用產(chǎn)品： Caki-1 細(xì)胞 , 786-O [786-0] 細(xì)胞 , 769-P 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , Caki-1細(xì)胞專用培養(yǎng)基 , 786-O [786-0]細(xì)胞專用培養(yǎng)基 , 769-P細(xì)胞專用培養(yǎng)基 , 293T [HEK-293T]細(xì)胞專用培養(yǎng)基
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產(chǎn)品資料
識(shí)別碼示意圖
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