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產(chǎn)品概述
| 名稱 | CAL-62 (人甲狀腺癌細(xì)胞(未分化)) (STR鑒定正確) |
| 別稱 | Cal-62; CAL 62; Cal 62; CAL62; Centre Antoine Lacassagne-62 |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
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| 推薦傳代比例 | 1:3-1:6 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | Established from the thyroid gland (right lobe) of a 70-year-old woman with thyroid anaplastic carcinoma in 1988; described as being tumorigenic in heterotransplanted nude mice |
| 年齡（性別） | 女性；70歲 |
| 組織來源 | 甲狀腺癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 甲狀腺癌細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~24 hours (DSMZ) |
| 保藏機(jī)構(gòu) | DSMZ; ACC-448 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 9,12 D2S1338 19,23 D3S1358 16 D5S818 9,12 D7S820 10 D8S1179 13 D13S317 12 D16S539 12,13 D18S51 16 D19S433 14 D21S11 32.2 FGA 19 PentaD 13 PentaE 5,10 TH01 7,9 TPOX 8,9 vWA 16 D6S1043 12 D12S391 22 D2S441 11 -
STR鑒定圖
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參考文獻(xiàn)
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Deciphering the role of the MALT1–RC3H1 axis in regulating GPX4 protein stability (2024-12-31)
期刊：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影響因子 ：9.4
引用產(chǎn)品： CAL-62 細(xì)胞
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Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D (2024-01-10)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c01622
影響因子 ：7.3
引用產(chǎn)品： CAL-62 細(xì)胞 , HCT 116 細(xì)胞 , AGS 細(xì)胞 , 重組人胰島素溶液 (10mg/mL)
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Cytotoxic and Antibacterial Meroterpenoids Isolated from the Marine-Derived Fungus Talaromyces sp. M27416 (2024-04-20)
期刊：Marine Drugs
影響因子 ：5.4
引用產(chǎn)品： K-562 [K562] 細(xì)胞 , TE-1 細(xì)胞 , HOS 細(xì)胞 , GBC-SD 細(xì)胞 , PaTu 8988t 細(xì)胞 , DU 145 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , SF126 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞 , HCT 116 細(xì)胞 , Hela 細(xì)胞 , A549 [A-549] 細(xì)胞 , Hep G2 細(xì)胞 , A-375 細(xì)胞 , MKN-45 細(xì)胞 , 5637 細(xì)胞 , 786-O [786-0] 細(xì)胞 , CAL-62 細(xì)胞 , A-673 細(xì)胞 , HL-7702 [L-02; LO2] 細(xì)胞
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UBR1 promotes anaplastic thyroid carcinoma progression via stabilizing YAP through monoubiquitylation (2024-08-22)
期刊：Scientific Reports
DOI：10.1038/s41598-024-70458-8
影響因子 ：3.8
引用產(chǎn)品： 青霉素-鏈霉素溶液（雙抗），100× , KHM-5M 細(xì)胞 , CAL-62 細(xì)胞
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C5AR1-induced TLR1/2 pathway activation drives proliferation and metastasis in anaplastic thyroid cancer (2024-06-27)
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23784
影響因子 ：3.0
引用產(chǎn)品： 8305C 細(xì)胞 , CAL-62 細(xì)胞 , Nthy-ori 3-1 細(xì)胞
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DNMT1/DNMT3a-mediated promoter hypermethylation and transcription activation of ICAM5 augments thyroid carcinoma progression (2024-01-17)
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-024-01293-3
影響因子 ：2.9
引用產(chǎn)品： B-CPAP [BC-PAP; BCPAP] 細(xì)胞 , 8305C 細(xì)胞 , BHT101 細(xì)胞 , CAL-62 細(xì)胞
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RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex (2023-02-21)
期刊：Cell and Bioscience
DOI：10.1186/s13578-023-00987-8
影響因子 ：7.5
引用產(chǎn)品： TPC-1 細(xì)胞 , B-CPAP [BC-PAP; BCPAP] 細(xì)胞 , KTC-1 細(xì)胞 , C643 細(xì)胞 , CAL-62 細(xì)胞 , 8305C 細(xì)胞 , KMH-2 細(xì)胞 , KHM-5M 細(xì)胞 , BHT101 細(xì)胞
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Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers (2023-03-10)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00075
影響因子 ：7.3
引用產(chǎn)品： Calu-1 細(xì)胞 , SW480 [SW-480] 細(xì)胞 , CAL-62 細(xì)胞 , LoVo 細(xì)胞 , HCT 116 細(xì)胞 , NCI-H460 [H460] 細(xì)胞
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Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer (2023-06-19)
期刊：APOPTOSIS
DOI：10.1007/s10495-023-01861-1
影響因子 ：7.2
引用產(chǎn)品： TPC-1 細(xì)胞 , 8305C 細(xì)胞 , BHT101 細(xì)胞 , CAL-62 細(xì)胞 , HTh-7 細(xì)胞
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Immunological characteristics of immunogenic cell death genes and malignant progression driving roles of TLR4 in anaplastic thyroid carcinoma (2023-11-21)
期刊：BMC CANCER
DOI：10.1186/s12885-023-11647-y
影響因子 ：3.8
引用產(chǎn)品： CAL-62 細(xì)胞
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Identification and Validation of Novel Genes in Anaplastic Thyroid Carcinoma via Bioinformatics Analysis (2023-01-30)
期刊：Cancer Management and Research
影響因子 ：3.3
引用產(chǎn)品： CAL-62 細(xì)胞
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Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway (2023-07-01)
期刊：CURRENT CANCER DRUG TARGETS
DOI：10.2174/1568009623666230118111745
影響因子 ：3.0
引用產(chǎn)品： TPC-1 細(xì)胞 , 8305C 細(xì)胞 , CAL-62 細(xì)胞 , BHT101 細(xì)胞
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Anti-Anaplastic Thyroid Cancer (ATC) Effects and Mechanisms of PLX3397 (Pexidartinib), a Multi-Targeted Tyrosine Kinase Inhibitor (TKI) (2022-12-28)
期刊：Cancers
影響因子 ：6.6
引用產(chǎn)品： CAL-62 細(xì)胞 , BHT101 細(xì)胞
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