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產(chǎn)品概述
| 名稱 | BHT101 (人甲狀腺癌細(xì)胞(未分化)) (STR鑒定正確) |
| 別稱 | BHT-101 |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:6 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | Established from the lymph node metastasis of a 63-year-old woman with anaplastic papillary thyroid carinoma; cells were described in the literature to not produce hormones, but to be partly positive for thyroglobulin- and thyroxine (T4) |
| 年齡（性別） | 女性；63歲 |
| 組織來源 | 甲狀腺癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 甲狀腺癌細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | 24 hours (PubMed=8099464); ~2-3 days (DSMZ) |
| 保藏機(jī)構(gòu) | DSMZ; ACC-279 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 12,13 D2S1338 20,23 D3S1358 16,17 D5S818 10,11 D7S820 10,11 D8S1179 13,15 D13S317 12 D16S539 9,11 D18S51 12,15 D19S433 13,14,15 D21S11 29,32.2 FGA 18,24 PentaD 9 PentaE 10,17 TH01 9,9.3 TPOX 8 vWA 19 D6S1043 12,14 D12S391 17,22 D2S441 10,11.3 -
STR鑒定圖
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參考文獻(xiàn)
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The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy (2024-04-28)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155670
影響因子 ：7.9
引用產(chǎn)品： DMEM高糖 培養(yǎng)基 , MEM（含NEAA） 培養(yǎng)基 , OCUT-2C 細(xì)胞 , 8305C 細(xì)胞 , RPMI-1640 培養(yǎng)基 , BHT101 細(xì)胞 , C643 細(xì)胞
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YTHDF2 promotes anaplastic thyroid cancer progression by activating the DDIT4/AKT/mTOR signaling pathway (2024-11-26)
期刊：Biology Direct
DOI：10.1186/s13062-024-00566-y
影響因子 ：5.7
引用產(chǎn)品： KHM-5M 細(xì)胞 , 特級(jí)胎牛血清 , KMH-2 細(xì)胞 , BHT101 細(xì)胞 , FTC-133 細(xì)胞
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DNMT1/DNMT3a-mediated promoter hypermethylation and transcription activation of ICAM5 augments thyroid carcinoma progression (2024-01-17)
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-024-01293-3
影響因子 ：2.9
引用產(chǎn)品： B-CPAP [BC-PAP; BCPAP] 細(xì)胞 , 8305C 細(xì)胞 , BHT101 細(xì)胞 , CAL-62 細(xì)胞
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RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex (2023-02-21)
期刊：Cell and Bioscience
DOI：10.1186/s13578-023-00987-8
影響因子 ：7.5
引用產(chǎn)品： TPC-1 細(xì)胞 , B-CPAP [BC-PAP; BCPAP] 細(xì)胞 , KTC-1 細(xì)胞 , C643 細(xì)胞 , CAL-62 細(xì)胞 , 8305C 細(xì)胞 , KMH-2 細(xì)胞 , KHM-5M 細(xì)胞 , BHT101 細(xì)胞
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Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer (2023-06-19)
期刊：APOPTOSIS
DOI：10.1007/s10495-023-01861-1
影響因子 ：7.2
引用產(chǎn)品： TPC-1 細(xì)胞 , 8305C 細(xì)胞 , BHT101 細(xì)胞 , CAL-62 細(xì)胞 , HTh-7 細(xì)胞
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Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway (2023-07-01)
期刊：CURRENT CANCER DRUG TARGETS
DOI：10.2174/1568009623666230118111745
影響因子 ：3.0
引用產(chǎn)品： TPC-1 細(xì)胞 , 8305C 細(xì)胞 , CAL-62 細(xì)胞 , BHT101 細(xì)胞
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FOXA2 suppresses PKM2 transcription and affects the Wnt/β-catenin activity to block aerobic glycolysis in thyroid carcinoma (2023-03-22)
期刊：CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
影響因子 ：2.9
引用產(chǎn)品： B-CPAP [BC-PAP; BCPAP] 細(xì)胞 , BHT101 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Anti-Anaplastic Thyroid Cancer (ATC) Effects and Mechanisms of PLX3397 (Pexidartinib), a Multi-Targeted Tyrosine Kinase Inhibitor (TKI) (2022-12-28)
期刊：Cancers
影響因子 ：6.6
引用產(chǎn)品： CAL-62 細(xì)胞 , BHT101 細(xì)胞
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Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways (2022-04-04)
期刊：MOLECULAR AND CELLULAR ENDOCRINOLOGY
影響因子 ：4.1
引用產(chǎn)品： 8305C 細(xì)胞 , BHT101 細(xì)胞
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