產(chǎn)品中心Cell Resources
聯(lián)系我們CONTACT US
400-999-210024小時服務(wù)熱線
產(chǎn)品概述
名稱 | LN229 [LN-229; LNT-229] (人膠質(zhì)母細胞瘤細胞) (STR鑒定正確) |
別稱 | LN 229; LN229; LNT-229 |
種屬 | 人 |
生長特性 | 貼壁細胞 |
細胞形態(tài) | 上皮細胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:3-1:5 |
推薦換液頻率 | 2-3次/周 |
背景描述 | The LN-229 cell line was Established in 1979 from cells taken from a patient with right frontal parieto-occipital glioblastoma [PubMed. 10416987]. |
年齡(性別) | 女性;60歲 |
組織來源 | 大腦/右額葉頂枕葉皮質(zhì) |
細胞類型 | 腫瘤細胞 |
腫瘤類型 | 膠質(zhì)母細胞瘤細胞 |
生物安全等級 | BSL-1 |
倍增時間 | ~31 hours |
致瘤性 | Yes, forms tumors in nude mice. |
保藏機構(gòu) | ATCC; CRL-2611 |
STR鑒定
-
STR位點信息
Amelogenin X CSF1PO 12 D2S1338 19,20 D3S1358 16,17 D5S818 11,12 D7S820 8,11 D8S1179 13,14 D13S317 10,11 D16S539 12 D18S51 13,15 D19S433 12,17.2 D21S11 29,30 FGA 23 PentaD 10,11 PentaE 7,16 TH01 9.3 TPOX 8 vWA 16,19 D6S1043 11 D12S391 20,22 D2S441 10,11 -
STR鑒定圖
-
參考文獻
-
NONHSAT141192.2 Facilitates the Stemness and Radioresistance of Glioma Stem Cells via the Regulation of PIK3R3 and SOX2 (2025-02-19)
期刊:CNS Neuroscience & Therapeutics
影響因子 :4.8
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U251 細胞
-
SPP1 as a Prognostic and Immunotherapeutic Biomarker in Gliomas and Other Cancer Types: A Pan-Cancer Study (2025-02-13)
期刊:Journal of Inflammation Research
影響因子 :4.2
引用產(chǎn)品: U251 細胞 , LN229 [LN-229; LNT-229] 細胞 , U-87 MG 細胞 , A172 細胞 , T98G 細胞 , 人神經(jīng)星形膠質(zhì)細胞
-
ARMC10 Drives Glioblastoma Progression Through Activating Notch Pathway (2025-02-23)
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23895
影響因子 :3.0
引用產(chǎn)品: A172 細胞 , U251 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , U-87 MG 細胞 , 青霉素-鏈霉素溶液(雙抗),100× , MEM(含NEAA) 培養(yǎng)基
-
Super-enhancer-driven LIF promotes the mesenchymal transition in glioblastoma by activating ITGB2 signaling feedback in microglia (2024-03-30)
期刊:NEURO-ONCOLOGY
影響因子 :15.9
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , SF126 細胞 , U-87 MG 細胞 , HMC3 細胞 , BV2 細胞
-
Sequential Release HydroLipo System for STING Gene Epigenetic Reprogramming and Immune Activation in Glioblastoma (2024-12-11)
期刊:Advanced Science
影響因子 :14.3
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞
-
Hypoxia-driven M2-polarized macrophages facilitate the epithelial-mesenchymal transition of glioblastoma via extracellular vesicles (2024-10-07)
期刊:Theranostics
影響因子 :12.4
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U-118 MG 細胞 , U251 細胞 , T98G 細胞 , A172 細胞 , THP-1 細胞
-
Hsa_circ_0021205 enhances lipolysis via regulating miR-195-5p/HSL axis and drives malignant progression of glioblastoma (2024-02-10)
期刊:Cell Death Discovery
DOI:10.1038/s41420-024-01841-7
影響因子 :7.0
引用產(chǎn)品: SNB-19 細胞 , LN229 [LN-229; LNT-229] 細胞 , U251 細胞 , T98G 細胞 , U-87 MG 細胞
-
EZH2–STAT3 signaling pathway regulates GSDMD-mediated pyroptosis in glioblastoma (2024-07-28)
期刊:Cell Death Discovery
DOI:10.1038/s41420-024-02105-0
影響因子 :6.1
引用產(chǎn)品: U-87 MG 細胞 , A172 細胞 , HA1800 細胞 , H4 細胞 , LN229 [LN-229; LNT-229] 細胞
-
Immune cell infiltration and drug response in glioblastoma multiforme: insights from oxidative stress-related genes (2024-04-02)
期刊:Cancer Cell International
DOI:10.1186/s12935-024-03316-2
影響因子 :5.8
引用產(chǎn)品: 人神經(jīng)星形膠質(zhì)細胞 , LN229 [LN-229; LNT-229] 細胞 , U251 細胞 , U-87 MG 細胞
-
A label-free electrochemical biosensor based on graphene quantum dots-nanoporous gold nanocomposite for highly sensitive detection of glioma cell (2024-12-16)
期刊:ANALYTICA CHIMICA ACTA
影響因子 :5.7
引用產(chǎn)品: U251 細胞 , NIH/3T3 細胞 , SCC7 細胞 , 4T1 細胞 , B16-F10 細胞 , Hela 細胞 , Hep G2 細胞 , LN229 [LN-229; LNT-229] 細胞 , PC-9 細胞 , LLC [LL/2; LLC1] 細胞 , hCMEC/D3 細胞 , HL-7702 [L-02; LO2] 細胞
-
Prognosis and therapeutic significance of IGF-1R-related signaling pathway gene signature in glioma (2024-04-11)
期刊:Frontiers in Cell and Developmental Biology
DOI:10.3389/fcell.2024.1375030
影響因子 :5.5
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U251 細胞 , T98G 細胞
-
A novel immunogenic cell death-related gene risk signature can identify biomarkers of gliomas and predict the immunotherapeutic response (2024-01-15)
期刊:American Journal of Cancer Research
DOI:PMID:38323285
影響因子 :5.3
引用產(chǎn)品: U251 細胞 , LN229 [LN-229; LNT-229] 細胞
-
TBX15 facilitates malignant progression of glioma by transcriptional activation of TXDNC5 (2024-01-18)
期刊:iScience
DOI:10.1016/j.isci.2024.108950
影響因子 :4.6
引用產(chǎn)品: 人神經(jīng)星形膠質(zhì)細胞 , U-118 MG 細胞 , A172 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , U251 細胞 , THP-1 細胞
-
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma (2024-03-11)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111137
影響因子 :4.4
引用產(chǎn)品: U-87 MG 細胞 , LN229 [LN-229; LNT-229] 細胞 , A172 細胞 , H4 細胞
-
TIFA enhances glycolysis through E2F1 and promotes the progression of glioma (2024-10-29)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111498
影響因子 :4.4
引用產(chǎn)品: A172 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , U251 細胞
-
CBX2 enhances the progression and TMZ chemoresistance of glioma via EZH2-mediated epigenetic silencing of PTEN expression (2024-07-24)
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2024.1430891
影響因子 :4.4
引用產(chǎn)品: T98G 細胞 , 青霉素-鏈霉素溶液(雙抗),100× , A172 細胞 , DMEM高糖 培養(yǎng)基 , LN229 [LN-229; LNT-229] 細胞
-
Repurposing flubendazole for glioblastoma ferroptosis by affecting xCT and TFRC proteins (2024-11-14)
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 :4.3
引用產(chǎn)品: U251 細胞 , LN229 [LN-229; LNT-229] 細胞
-
Exploration of the biological mechanisms of CENPA as an oncogene in glioma: Screening based on cancer functional status (2024-12-02)
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 :4.3
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U251 細胞
-
Phospholipid scramblase 1 acts through the IL-6/JAK/STAT3 pathway to promote the malignant progression of glioma (2024-04-16)
期刊:ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影響因子 :3.9
引用產(chǎn)品: A172 細胞 , T98G 細胞 , U251 細胞 , LN229 [LN-229; LNT-229] 細胞 , U-87 MG 細胞
-
Transcription factor YY1-activated GNG5 facilitates glioblastoma cell growth, invasion, stemness and glycolysis through Wnt/β-catenin pathway (2024-10-24)
期刊:Scientific Reports
DOI:10.1038/s41598-024-76019-3
影響因子 :3.8
引用產(chǎn)品: U251 細胞 , LN229 [LN-229; LNT-229] 細胞 , A172 細胞 , 人神經(jīng)星形膠質(zhì)細胞
-
Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway (2024-03-28)
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-024-05625-5
影響因子 :3.6
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U-87 MG 細胞
-
Comprehensive pan-cancer analysis of ACSS3 as a biomarker for prognosis and immunotherapy response (2024-07-27)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e35231
影響因子 :3.4
引用產(chǎn)品: 人神經(jīng)星形膠質(zhì)細胞 , U251 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , U-87 MG 細胞
-
TMEM17 Promotes Tumor Progression in Glioblastoma by Activating the PI3K/AKT Pathway (2024-08-16)
期刊:Frontiers in Bioscience-Landmark
影響因子 :3.3
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U-87 MG 細胞
-
Regulation of a novel circATP8B4/miR-31-5p/nestin ceRNA crosstalk in proliferation, motility, invasion and radiosensitivity of human glioma cells (2024-09-17)
期刊:JOURNAL OF RADIATION RESEARCH
影響因子 :1.9
引用產(chǎn)品: T98G 細胞 , HMC3 細胞 , U251 細胞 , A172 細胞 , LN229 [LN-229; LNT-229] 細胞
-
NLRP6 potentiates PI3K/AKT signalling by promoting autophagic degradation of p85α to drive tumorigenesis (2023-09-28)
期刊:Nature Communications
DOI:10.1038/s41467-023-41739-z
影響因子 :16.6
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞
-
Multi-omics analysis reveals the involvement of origin recognition complex subunit 6 in tumor immune regulation and malignant progression (2023-10-12)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1236806
影響因子 :7.3
引用產(chǎn)品: Hep G2 細胞 , U251 細胞 , LN229 [LN-229; LNT-229] 細胞
-
Nifuroxazide inhibits the growth of glioblastoma and promotes the infiltration of CD8 T cells to enhance antitumour immunity (2023-03-14)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.109987
影響因子 :5.6
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U251 細胞 , T98G 細胞 , A172 細胞 , 人臍靜脈內(nèi)皮細胞 , GL261 細胞 , BV2 細胞
-
A TGF-β signaling-related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response (2023-10-18)
期刊:CNS Neuroscience & Therapeutics
影響因子 :5.5
引用產(chǎn)品: T98G 細胞 , U251 細胞 , LN229 [LN-229; LNT-229] 細胞
-
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma. (2023-10-17)
期刊:Aging-US
影響因子 :5.2
引用產(chǎn)品: U-118 MG 細胞 , U251 細胞 , U-87 MG 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , SVG 細胞 , 293T [HEK-293T] 細胞
-
Tumor-suppressive function and mechanism of miR-873-5p in glioblastoma: evidence based on bioinformatics analysis and experimental validation (2023-06-28)
期刊:Aging-US
影響因子 :5.2
引用產(chǎn)品: 293T [HEK-293T] 細胞 , T98G 細胞 , U251 細胞 , LN229 [LN-229; LNT-229] 細胞 , A172 細胞
-
Zinc finger and SCAN domain-containing 18 suppresses the proliferation, self-renewal, and drug resistance of glioblastoma cells (2023-06-03)
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e17000
影響因子 :4.0
引用產(chǎn)品: U251 細胞 , SHG-44 細胞 , LN229 [LN-229; LNT-229] 細胞 , U-87 MG 細胞
-
Cordycepin improves sensitivity to temozolomide in glioblastoma cells by down-regulating MYC (2023-09-11)
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-023-05347-0
影響因子 :3.6
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞
-
VSIG4 Silencing Inhibits Glioblastoma Growth by Regulating the JAK2/STAT3 Pathway (2023-06-02)
期刊:Neuropsychiatric Disease and Treatment
影響因子 :3.2
引用產(chǎn)品: U251 細胞 , LN229 [LN-229; LNT-229] 細胞 , U251細胞專用培養(yǎng)基 , LN229 [LN-229; LNT-229]細胞專用培養(yǎng)基
-
HNF4G accelerates glioma progression by facilitating NRP1 transcription (2023-02-01)
期刊:Oncology Letters
影響因子 :2.9
引用產(chǎn)品: U-87 MG 細胞 , LN229 [LN-229; LNT-229] 細胞 , U251 細胞
-
Cytotoxicity sesquiterpenoids from the leaves of Datura stramonium L. (2023-05-17)
期刊:NATURAL PRODUCT RESEARCH
DOI:10.1080/14786419.2023.2214292
影響因子 :2.2
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞
-
SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma (2022-12-24)
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-05526-w
影響因子 :9.7
引用產(chǎn)品: U-87 MG 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , U373 細胞 , HA1800 細胞 , THP-1 細胞
-
RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12 (2022-11-15)
期刊:CNS Neuroscience & Therapeutics
影響因子 :7.0
引用產(chǎn)品: 人神經(jīng)星形膠質(zhì)細胞 , U251 細胞 , A172 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , U-118 MG 細胞 , THP-1 細胞
-
A novel necroptosis-related gene signature for predict prognosis of glioma based on single-cell and bulk RNA sequencing (2022-08-30)
期刊:Frontiers in Molecular Biosciences
影響因子 :6.1
引用產(chǎn)品: U-118 MG 細胞 , U138 細胞 , LN229 [LN-229; LNT-229] 細胞 , HS 683 細胞 , U-118 MG細胞專用培養(yǎng)基 , U138 細胞專用培養(yǎng)基 , LN229 [LN-229; LNT-229]細胞專用培養(yǎng)基 , HS 683細胞專用培養(yǎng)基
-
Propofol inhibits glioma progression by regulating circMAPK4/miR-622/HOXA9 axis (2022-11-03)
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01099-x
影響因子 :3.7
引用產(chǎn)品: U251 細胞 , LN229 [LN-229; LNT-229] 細胞
-
Circ_0001588 Upregulates ERBB4 to Promote Glioma Malignant Progression Through Sponging miR-1281 (2022-01-04)
期刊:Neurotoxicity Research
DOI:10.1007/s12640-021-00464-5
影響因子 :3.7
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , U251 細胞
-
Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy (2021-08-06)
期刊:Acta Pharmacologica Sinica
DOI:10.1038/s41401-021-00724-2
影響因子 :8.2
引用產(chǎn)品: U-87 MG 細胞 , U-118 MG 細胞 , A172 細胞 , T98G 細胞 , LN229 [LN-229; LNT-229] 細胞 , MCF 10A 細胞
-
Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients (2021-05-29)
期刊:Molecular Medicine
DOI:10.1186/s10020-021-00316-0
影響因子 :5.7
引用產(chǎn)品: HA 細胞 , Marcus 細胞 細胞 , A172 細胞 , U251 細胞
-
Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis (2021-08-31)
期刊:Bioengineered
DOI:10.1080/21655979.2021.1976712
影響因子 :4.9
引用產(chǎn)品: LN229 [LN-229; LNT-229] 細胞 , T98G 細胞 , A172 細胞
-
Knockdown of long non-coding RNA AGAP2-AS1 suppresses the proliferation and metastasis of glioma by targeting microRNA-497-5p (2021-10-28)
期刊:Bioengineered
DOI:10.1080/21655979.2021.1995573
影響因子 :4.9
引用產(chǎn)品: SHG-44 細胞 , LN229 [LN-229; LNT-229] 細胞 , DMEM高糖 培養(yǎng)基 , 特級胎牛血清 , 青霉素-鏈霉素溶液 (雙抗),100×
-
The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells (2021-11-18)
期刊:Frontiers in Oncology
影響因子 :4.7
引用產(chǎn)品: U-87 MG 細胞 , LN229 [LN-229; LNT-229] 細胞 , U251 細胞 , T98G 細胞
-
CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis (2021-10-09)
期刊:Bmc Cancer
DOI:10.1186/s12885-021-08803-7
影響因子 :3.8
引用產(chǎn)品: SHG-44 細胞 , U251 細胞 , LN229 [LN-229; LNT-229] 細胞 , A172 細胞 , T98G 細胞
-
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma (2021-09-28)
期刊:Biomed Research International
影響因子 :3.4
引用產(chǎn)品: 人神經(jīng)星形膠質(zhì)細胞 , LN229 [LN-229; LNT-229] 細胞 , T98G 細胞 , U251 細胞 , A172 細胞
-
CircFOXM1 promotes the proliferation, migration, invasion, and glutaminolysis of glioblastoma by regulating the miR-577/E2F5 axis (2021-06-28)
期刊:Bosnian Journal of Basic Medical Sciences
影響因子 :3.4
引用產(chǎn)品: 青霉素-鏈霉素溶液 (雙抗),100× , U251 細胞 , LN229 [LN-229; LNT-229] 細胞 , A172 細胞 , 人神經(jīng)星形膠質(zhì)細胞
-
MSC-AS1 knockdown inhibits cell growth and temozolomide resistance by regulating miR-373-3p/CPEB4 axis in glioma through PI3K/Akt pathway (2020-10-26)
期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI:10.1007/s11010-020-03937-x
影響因子 :4.3
引用產(chǎn)品: SHG-44 細胞 , 293T [HEK-293T] 細胞 , LN229 [LN-229; LNT-229] 細胞
-
Sevoflurane Represses Proliferation and Migration of Glioma Cells by Regulating the ANRIL/let-7b-5p Axis (2020-08-19)
期刊:Cancer Biother And Radiopharm
影響因子 :3.4
引用產(chǎn)品: U251 細胞 , LN229 [LN-229; LNT-229] 細胞
-
CircTTBK2 Contributes to the Progression of Glioma Through Regulating miR-145-5p/CPEB4 Axis (2020-09-08)
期刊:Cancer Management and Research
影響因子 :3.3
引用產(chǎn)品: T98G 細胞 , LN229 [LN-229; LNT-229] 細胞
FAQs
Q:{{item.question}}
A:
產(chǎn)品資料


識別碼示意圖