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產(chǎn)品概述
| 名稱(chēng) | Raji (人Burkitt's淋巴瘤細(xì)胞) (STR鑒定正確) |
| 別稱(chēng) | RAJI; P1-Raji; GM04671 |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 懸浮細(xì)胞 |
| 細(xì)胞形態(tài) | 淋巴母細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 4×10^5cells/mL |
| 推薦換液頻率 | 2-3次/周 |
| 注意事項(xiàng) | 該細(xì)胞為懸浮細(xì)胞，請(qǐng)注意離心收集細(xì)胞懸液；請(qǐng)勿直接倒掉細(xì)胞培養(yǎng)液。 |
| 背景描述 | Raji細(xì)胞由PulvertaftRJV于1963年從一位11歲黑人男孩的左上頜骨的Burkitt淋巴瘤中分離建立的，是第一個(gè)人類(lèi)造血系統(tǒng)的連續(xù)傳代細(xì)胞，為B細(xì)胞起源。該細(xì)胞中含有EBV，可作轉(zhuǎn)染宿主。 |
| 年齡（性別） | 男性；11歲 |
| 組織來(lái)源 | B淋巴細(xì)胞；Burkitt's淋巴瘤 |
| 細(xì)胞類(lèi)型 | 腫瘤細(xì)胞 |
| 腫瘤類(lèi)型 | 淋巴瘤細(xì)胞 |
| 生物安全等級(jí) | BSL-2 |
| 倍增時(shí)間 | ~24-36 hours |
| 保藏機(jī)構(gòu) | ATCC; CCL-86 ATCC; CRL-7936DSMZ; ACC-319 ECACC; 85011429 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 22 D3S1358 15,16 D5S818 10,13 D7S820 10 D8S1179 14,15 D13S317 13 D16S539 8,11 D18S51 17 D19S433 14,14.2 D21S11 28,31 FGA 19,27 PentaD 3.2,9 PentaE 5,13 TH01 6,7 TPOX 8,13 vWA 17,19 D6S1043 21 D12S391 18,19 D2S441 11,12 -
STR鑒定圖
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參考文獻(xiàn)
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Development and therapeutic assessment of bispecific nanobodies targeting B-cell activating factor and interleukin-17 for the neutralization of inflammatory mediators in autoimmune diseases (2025-01-25)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2025.140057
影響因子 ：7.7
引用產(chǎn)品： Raji 細(xì)胞 , HT-29 細(xì)胞 , McCoy's 5A 培養(yǎng)基
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Sialic Acid-Modified NIR-II Fluorophore with Enhanced Brightness and Photoconversion Capability for Targeted Lymphoma Phototheranostics (2025-01-25)
期刊：ANALYTICAL CHEMISTRY
DOI：10.1021/acs.analchem.4c06424
影響因子 ：6.7
引用產(chǎn)品： Raji 細(xì)胞 , 4T1 細(xì)胞 , Hela 細(xì)胞 , NCTC clone 929 [L cell, L-929] 細(xì)胞
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Risk Allele rs117026326-Mediated Alternative Splicing of GTF2I Promotes B Cell Proliferation in Primary Sj?gren’s Syndrome (2025-02-18)
期刊：Journal of Immunology Research
影響因子 ：3.5
引用產(chǎn)品： Raji 細(xì)胞 , Ramos [RA 1] 細(xì)胞 , Jurkat clone A3[A3] 細(xì)胞 , THP-1 細(xì)胞
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Insights into oral lentinan immunomodulation: Dectin-1-mediated lymphatic transport from Peyer's patch M cells to mononuclear phagocytes (2024-08-08)
期刊：CARBOHYDRATE POLYMERS
DOI：10.1016/j.carbpol.2024.122586
影響因子 ：10.7
引用產(chǎn)品： Caco-2 細(xì)胞 , Raji 細(xì)胞
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Structure-based design of antibodies targeting the EBNA1 DNA-binding domain to block Epstein–Barr virus latent infection and tumor growth (2024-10-10)
期刊：MedComm
DOI：10.1002/mco2.739
影響因子 ：10.7
引用產(chǎn)品： Raji 細(xì)胞
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Original research: Fc–Fc interactions and immune inhibitory effects of IgG4: implications for anti-PD-1 immunotherapies (2024-06-25)
期刊：Journal for ImmunoTherapy of Cancer
影響因子 ：10.3
引用產(chǎn)品： Raji 細(xì)胞 , THP-1細(xì)胞專(zhuān)用培養(yǎng)基 , THP-1 細(xì)胞 , BT-474 [BT474]細(xì)胞專(zhuān)用培養(yǎng)基 , BT-474 [BT474] 細(xì)胞
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CX-5461 ameliorates disease in lupus-prone mice by triggering B-cell ferroptosis via p53-SLC7A11-ALOX12 pathway (2024-08-05)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.08.003
影響因子 ：7.1
引用產(chǎn)品： 293T [HEK-293T] 細(xì)胞 , Raji 細(xì)胞
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Hypoimmunogenic CD19 CAR-NK cells derived from embryonic stem cells suppress the progression of human B-cell malignancies in xenograft animals (2024-11-27)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1504459
影響因子 ：5.7
引用產(chǎn)品： Raji 細(xì)胞
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Broadening anticancer spectrum by preprocessing and treatment of T- lymphocytes expressed FcγRI and monoclonal antibodies for refractory cancers (2024-06-17)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1400177
影響因子 ：5.7
引用產(chǎn)品： 293T [HEK-293T] 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , MCF 10A 細(xì)胞 , MDA-MB-231 細(xì)胞 , Jurkat76 細(xì)胞 , SK-OV-3 細(xì)胞 , K-562 [K562] 細(xì)胞 , MKN-45 細(xì)胞 , Daudi 細(xì)胞 , 人外周血單核細(xì)胞 , SGC-7901 細(xì)胞 , Raji 細(xì)胞 , HCT 116 細(xì)胞
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MiR-525-5p modulates cell proliferation, cell cycle, and apoptosis in Burkitt’s lymphoma by targeting MyD88 and regulating the NF-κB signaling pathway (2024-11-04)
期刊：ANNALS OF HEMATOLOGY
DOI：10.1007/s00277-024-06062-7
影響因子 ：3.0
引用產(chǎn)品： Raji 細(xì)胞 , Ramos [RA 1] 細(xì)胞
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Label-free, rapid and highly accurate identification and categorization of leukemia cells via Raman spectroscopy (2023-08-22)
期刊：SENSORS AND ACTUATORS B-CHEMICAL
影響因子 ：8.4
引用產(chǎn)品： K-562 [K562] 細(xì)胞 , U-937 細(xì)胞 , Raji 細(xì)胞 , Jurkat, Clone E6-1 細(xì)胞 , K-562 [K562]細(xì)胞專(zhuān)用培養(yǎng)基 , U-937細(xì)胞專(zhuān)用培養(yǎng)基 , Raji細(xì)胞專(zhuān)用培養(yǎng)基 , Jurkat, Clone E6-1細(xì)胞專(zhuān)用培養(yǎng)基
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BLK positively regulates TLR/IL-1R signaling by catalyzing TOLLIP phosphorylation (2023-12-11)
期刊：JOURNAL OF CELL BIOLOGY
影響因子 ：7.8
引用產(chǎn)品： U-87 MG 細(xì)胞 , Jurkat, Clone E6-1 細(xì)胞 , Raji 細(xì)胞 , A20 細(xì)胞
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RGD-modified solid lipid nanoparticles improve oral doxorubicin absorption: In vitro and in vivo study (2023-12-19)
期刊：JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI：10.1016/j.jddst.2023.105293
影響因子 ：5.0
引用產(chǎn)品： Caco-2 細(xì)胞 , Raji 細(xì)胞
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CD146+ Umbilical Cord Mesenchymal Stem Cells Exhibit High Immunomodulatory Activity and Therapeutic Efficacy in Septic Mice (2023-02-10)
期刊：Journal of Inflammation Research
影響因子 ：4.5
引用產(chǎn)品： RAW 264.7 細(xì)胞 , Raji 細(xì)胞
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Long non-coding RNA SNHG17 may function as a competitive endogenous RNA in diffuse large B-cell lymphoma progression by sponging miR-34a-5p (2023-11-21)
期刊：PLoS One
DOI：10.1371/journal.pone.0294729
影響因子 ：3.7
引用產(chǎn)品： Daudi 細(xì)胞 , Ramos [RA 1] 細(xì)胞 , DoHH2 細(xì)胞 , Farage 細(xì)胞 , Raji 細(xì)胞
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