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產(chǎn)品概述
| 名稱 | MOLM-13 (人急性髓性白血病細(xì)胞) (STR鑒定正確) |
| 別稱 | MOLM13; Molm13; Molm 13 |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 懸浮細(xì)胞 |
| 細(xì)胞形態(tài) | 淋巴細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:6 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | established from the peripheral blood of a 20-year-old man with acute myeloid leukemia AML FAB M5a at relapse in 1995 after initial myelodysplastic syndrome (MDS, refractory anemia with excess of blasts, RAEB); described to carry internal tandem duplication of FLT3; the FLT3 protein is not expressed; cell line carries the CBL deltaExon8 mutant; sister cell line of MOLM-14 (ACC 777). Exome and RNA sequence data are available (see Ref 18187 and Exome sequence and RNA-Seq)。 |
| 年齡（性別） | 男性；20歲 |
| 組織來源 | 外周血 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 白血病細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | 3-4 days (PubMed=9305600); 24 hours (PubMed=25984343); 41.1 hours (PubMed=28052028); ~50 hours (DSMZ=ACC-554) |
| 保藏機(jī)構(gòu) | DSMZ; ACC-554 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X, Y CSF1PO 10,12 D2S1338 23,25 D3S1358 15 D5S818 10,11 D7S820 10,12 D8S1179 13,14 D13S317 10,11 D16S539 10,11 D18S51 13,15 D19S433 12,14 D21S11 30,31 FGA 21,23 PentaD 9,12 PentaE 18,19 TH01 7 TPOX 8 vWA 16,17 D6S1043 12,14 D12S391 15,19 D2S441 11,12 -
STR鑒定圖
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參考文獻(xiàn)
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Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin (2024-07-01)
期刊：Journal for ImmunoTherapy of Cancer
影響因子 ：10.3
引用產(chǎn)品： NK-92 細(xì)胞 , MKN-45 細(xì)胞 , Eca-109 細(xì)胞 , IM95 細(xì)胞 , 293T/17 細(xì)胞 , MOLM-13 細(xì)胞
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Activation of non-classical Wnt signaling pathway effectively enhances HLA-A presentation in acute myeloid leukemia (2024-06-19)
期刊：Frontiers in Oncology
影響因子 ：3.5
引用產(chǎn)品： MOLM-13 細(xì)胞 , 人骨髓造血干細(xì)胞完全培養(yǎng)基 , 人骨髓造血干細(xì)胞 , HL-60 細(xì)胞 , THP-1 細(xì)胞
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Integrated analysis and validation reveal CYTH4 as a potential prognostic biomarker in acute myeloid leukemia (2024-01-16)
期刊：Oncology Letters
影響因子 ：2.9
引用產(chǎn)品： NOMO-1 細(xì)胞 , MOLM-13 細(xì)胞 , NB4 細(xì)胞 , BALL-1 細(xì)胞 , NALM-6 細(xì)胞 , SUP-B15 細(xì)胞
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Correlating gene expression levels with transcription factor binding sites facilitates identification of key transcription factors from transcriptome data (2024-11-29)
期刊：Frontiers in Genetics
DOI：10.3389/fgene.2024.1511456
影響因子 ：2.8
引用產(chǎn)品： MOLM-13 細(xì)胞 , HL-60 細(xì)胞 , U-937 細(xì)胞 , OCI-AML-3 細(xì)胞
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