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產(chǎn)品概述
| 名稱(chēng) | NCTC 1469 (小鼠正常肝細(xì)胞) (STR鑒定正確) |
| 別稱(chēng) | NCTC clone 1469; NCTC1469 |
| 種屬 | 小鼠 |
| 生長(zhǎng)特性 | 半貼半懸 |
| 細(xì)胞形態(tài) | 圓形、上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 注意事項(xiàng) | 該細(xì)胞生長(zhǎng)狀態(tài)為半貼半懸，貼壁部分處理時(shí)需要用胰酶消化。培養(yǎng)時(shí)，間隔處理時(shí)間過(guò)長(zhǎng)會(huì)導(dǎo)致細(xì)胞貼壁部分消化時(shí)間延長(zhǎng)。 |
| 背景描述 | NCTC 1469細(xì)胞是于1952年建系，源于正常C3H/An小鼠的肝臟組織；NCTC 1469細(xì)胞可表達(dá)H-2K抗原，鼠痘病毒陰性。 |
| 年齡（性別） | 新生 |
| 組織來(lái)源 | 肝臟 |
| 細(xì)胞類(lèi)型 | 自發(fā)永生化細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 保藏機(jī)構(gòu) | ATCC; CCL-9.1 ECACC; 88111403 |
STR鑒定
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STR位點(diǎn)信息
18-3 16 6-7 12 5-5 15 X-1 26 1-2 16 7-1 26,27 8-1 14,16 1-1 10 19-2 11,12 15-3 25.3 12-1 16 6-4 18 4-2 20.3 3-2 14,15 2-1 9 13-1 17.1，18.1
11-2 16,18 17-2 15,16,17 -
STR鑒定圖
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參考文獻(xiàn)
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The enhancing effects and mechanisms of inositol and choline on antioxidant capacity of vitamin E using model established in mice hepatocytes (2025-01-02)
期刊：Nutrition & Food Science
影響因子 ：1.0
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury (2024-01-01)
期刊：Theranostics
影響因子 ：12.4
引用產(chǎn)品： NCTC 1469 細(xì)胞 , THP-1 細(xì)胞 , 馬血清
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Liver Extracellular Vesicles and Particles Enriched β-Sitosterol Effectively Promote Liver Regeneration in Mice (2024-08-07)
期刊：International Journal of Nanomedicine
影響因子 ：6.6
引用產(chǎn)品： NCTC 1469細(xì)胞專(zhuān)用培養(yǎng)基 , NCTC 1469 細(xì)胞
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Chemically synthesized osteocalcin alleviates NAFLD via the AMPK-FOXO1/BCL6-CD36 pathway (2024-08-22)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05592-y
影響因子 ：6.1
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Supplementation of Mangiferin to a High-Starch Diet Alleviates Hepatic Injury and Lipid Accumulation Potentially through Modulating Cholesterol Metabolism in Channel Catfish (Ictalurus punctatus) (2024-06-13)
期刊：Antioxidants
影響因子 ：6.0
引用產(chǎn)品： NCTC 1469 細(xì)胞
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CBX7 silencing promoted liver regeneration by interacting with BMI1 and activating the Nrf2/ARE signaling pathway (2024-05-14)
期刊：Scientific Reports
DOI：10.1038/s41598-024-58248-8
影響因子 ：4.6
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Optimization of concentrations of different n-3PUFAs on antioxidant capacity in mouse hepatocytes (2024-07-09)
期刊：Lipids in Health and Disease
DOI：10.1186/s12944-024-02202-0
影響因子 ：3.9
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Mechanisms of Yiai Fuzheng formula in the treatment of triple-negative breast cancer based on UPLC-Q-Orbitrap-HRMS, network pharmacology, and experimental validation (2024-08-19)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e36579
影響因子 ：3.4
引用產(chǎn)品： NIH/3T3 細(xì)胞 , NCTC 1469 細(xì)胞 , 4T1 細(xì)胞 , MDA-MB-231 細(xì)胞
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Pretreatment of artesunate promoted hepatocyte proliferation by activating the PI3K/Akt/mTOR signaling pathway in mice (2024-10-25)
期刊：Acta Cirurgica Brasileira
影響因子 ：1.1
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Natural long-chain saturated fatty acids doped LNPs enabling spleen selective mRNA translation and potent cancer immunotherapy (2023-09-08)
期刊：Nano Research
影響因子 ：9.9
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Perfluorooctane sulfonate (PFOS), a novel environmental pollutant, induces liver injury in mice by activating hepatocyte ferroptosis (2023-10-27)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115625
影響因子 ：6.8
引用產(chǎn)品： AML12 細(xì)胞 , AML-12細(xì)胞專(zhuān)用培養(yǎng)基
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Resmetirom Ameliorates NASH-Model Mice by Suppressing STAT3 and NF-κB Signaling Pathways in an RGS5-Dependent Manner (2023-03-19)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.6
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Uncarboxylated Osteocalcin Decreases SCD1 by Activating AMPK to Alleviate Hepatocyte Lipid Accumulation (2023-03-31)
期刊：MOLECULES
影響因子 ：4.6
引用產(chǎn)品： NCTC 1469 細(xì)胞 , DMEM高糖 培養(yǎng)基 , 馬血清
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The Different Mechanisms of Lipid Accumulation in Hepatocytes Induced by Oleic Acid/Palmitic Acid and High-Fat Diet (2023-09-20)
期刊：MOLECULES
影響因子 ：4.6
引用產(chǎn)品： NCTC 1469 細(xì)胞 , DMEM高糖 培養(yǎng)基 , 馬血清
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Effects of protoscoleces excretory-secretory products of Echinococcus granulosus on hepatocyte growth, function, and glucose metabolism (2023-11-08)
期刊：ACTA TROPICA
DOI：10.1016/j.actatropica.2023.107066
影響因子 ：2.7
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Dietary intake of fructose increases purine de novo synthesis: A crucial mechanism for hyperuricemia (2022-12-19)
期刊：Frontiers in Nutrition
影響因子 ：6.6
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Periplaneta americana extract alleviates steatohepatitis in a mouse model by modulating HMGB1-mediated inflammatory response (2022-10-03)
期刊：Frontiers in Pharmacology
影響因子 ：6.0
引用產(chǎn)品： NCTC 1469 細(xì)胞 , J774A.1 細(xì)胞
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RNA-seq transcriptome profiling of liver regeneration in mice identifies the miR-34b-5p/phosphoinositide-dependent protein kinase 1 axis as a potential target for hepatocyte proliferation (2022-08-21)
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2022.08.049
影響因子 ：3.3
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Inhibition of GCN2 alleviates hepatic steatosis and oxidative stress in obese mice: Involvement of NRF2 regulation (2021-12-22)
期刊：Redox Biology
DOI：10.1016/j.redox.2021.102224
影響因子 ：11.4
引用產(chǎn)品： NCTC 1469 細(xì)胞
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Downregulated long non-coding RNA LINC01093 in liver fibrosis promotes hepatocyte apoptosis via increasing ubiquitination of SIRT1 (2020-05-01)
期刊：Journal Of Biochemistry
影響因子 ：2.7
引用產(chǎn)品： NCTC 1469 細(xì)胞
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