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產(chǎn)品概述
名稱 | YAC-1 (小鼠淋巴瘤細(xì)胞) (STR鑒定正確) |
別稱 | Yac-1; YAC |
種屬 | 小鼠 |
生長特性 | 懸浮細(xì)胞 |
細(xì)胞形態(tài) | 淋巴母細(xì)胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 3×10^5-5×10^5cells/mL |
推薦換液頻率 | 2-3次/周 |
注意事項(xiàng) | 該細(xì)胞為懸浮細(xì)胞,請注意離心收集細(xì)胞懸液;請勿直接倒掉細(xì)胞培養(yǎng)液。 |
背景描述 | YAC-1是一個(gè)淋巴瘤細(xì)胞,將Moloney白血病病毒(MLV)接種到新生A/Sn小鼠中生成。YAC-1細(xì)胞對NK細(xì)胞的活動(dòng)敏感,對于NK細(xì)胞活性檢測十分有用。 |
年齡(性別) | 不詳 |
組織來源 | Moloney鼠科白血病毒(Mo-MuLV)感染;淋巴瘤 |
細(xì)胞類型 | 腫瘤細(xì)胞 |
腫瘤類型 | 淋巴瘤細(xì)胞 |
生物安全等級 | BSL-2 |
倍增時(shí)間 | ~20 hours |
保藏機(jī)構(gòu) | ATCC; TIB-160 DSMZ; ACC-96 ECACC; 86022801 |
STR鑒定
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STR位點(diǎn)信息
18-3 18 6-7 12 5-5 16 X-1 26 1-2 17,18 7-1 25.2 8-1 16 1-1 11 19-2 12,13 15-3 22.3 12-1 16 6-4 18 4-2 21.3 3-2 14 2-1 16 13-1 16.2,17.2
11-2 15 17-2 16 -
STR鑒定圖
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參考文獻(xiàn)
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Down-regulation of zinc finger protein 335 undermines natural killer cell function in mouse colitis-associated colorectal carcinoma (2024-02-07)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e25721
影響因子 :3.4
引用產(chǎn)品: YAC-1 細(xì)胞
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Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner (2023-02-03)
期刊:Cancer Immunology Research
DOI:10.1158/2326-6066.CIR-22-0439
影響因子 :10.1
引用產(chǎn)品: Jurkat, Clone E6-1 細(xì)胞 , RKO 細(xì)胞 , CT26.WT 細(xì)胞 , B16-F10 細(xì)胞 , MC38 細(xì)胞 , 4T1 細(xì)胞 , LLC [LL/2; LLC1] 細(xì)胞 , Hepa 1-6 細(xì)胞 , YAC-1 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , AAV-293 細(xì)胞 , STR鑒定
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Sirtuin 2 up-regulation suppresses the anti-tumour activity of exhausted natural killer cells in mesenteric lymph nodes in murine colorectal carcinoma (2023-08-07)
期刊:SCANDINAVIAN JOURNAL OF IMMUNOLOGY
影響因子 :3.7
引用產(chǎn)品: YAC-1 細(xì)胞
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Sirtuin 6 is a negative regulator of the anti-tumor function of natural killer cells in murine inflammatory colorectal cancer (2023-05-03)
期刊:MOLECULAR IMMUNOLOGY
DOI:10.1016/j.molimm.2023.04.011
影響因子 :3.6
引用產(chǎn)品: YAC-1 細(xì)胞
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Fabrication of a Silk Sericin Hydrogel System Delivering Human Lactoferrin Using Genetically Engineered Silk with Improved Bioavailability to Alleviate Chemotherapy-Induced Immunosuppression (2021-09-16)
期刊:ACS Applied Materials & Interfaces
影響因子 :10.4
引用產(chǎn)品: Caco-2 細(xì)胞 , YAC-1 細(xì)胞
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Down-regulation of PR/SET domain 10 underlies natural killer cell dysfunction in hepatocellular carcinoma (2021-10-10)
期刊:Clinical And Experimental Immunology
影響因子 :4.6
引用產(chǎn)品: YAC-1 細(xì)胞
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