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ES-2 (人卵巢透明細(xì)胞癌細(xì)胞) (STR鑒定正確)
貨號(hào)：CL-0079
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價(jià)格： ￥1600
生長(zhǎng)培養(yǎng)基：McCoy’s 5A＋10% FBS＋1% P/S
產(chǎn)品概述
| 名稱(chēng) | ES-2 (人卵巢透明細(xì)胞癌細(xì)胞) (STR鑒定正確) |
| 別稱(chēng) | ES2 |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 成纖維細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
生長(zhǎng)培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | ES-2細(xì)胞是建自45歲女性黑人的外科腫瘤標(biāo)本，該腫瘤為低分化卵巢透明細(xì)胞癌。ES-2細(xì)胞最初生長(zhǎng)在軟瓊脂中；ES-2細(xì)胞在裸鼠中成瘤。ES-2細(xì)胞對(duì)多種化療藥物包括阿霉素、順鉑、卡氯芥、依托泊甙等表現(xiàn)出低到中等的耐受性；ES-2細(xì)胞表達(dá)低水平的P糖蛋白。 |
| 年齡（性別） | 女性；47歲 |
| 組織來(lái)源 | 透明細(xì)胞癌，卵巢 |
| 細(xì)胞類(lèi)型 | 腫瘤細(xì)胞 |
| 腫瘤類(lèi)型 | 卵巢癌細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~28-36 hours |
| 致瘤性 | Yes, tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells. |
| 基因表達(dá)情況 | P glycoprotein |
| 保藏機(jī)構(gòu) | ATCC; CRL-1978 BCRC; 60067 BCRJ; 0080 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 10,15 D2S1338 17,23 D3S1358 15,18 D5S818 11,13 D7S820 11 D8S1179 14 D13S317 11 D16S539 11,13 D18S51 13,15 D19S433 15,15.2 D21S11 32.2,33.2 FGA 21 PentaD 8,13 PentaE 13,16 TH01 9.3 TPOX 8,12 vWA 16,17 D6S1043 11,12 D12S391 20,21 D2S441 11 -
STR鑒定圖
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參考文獻(xiàn)
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GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer (2024-04-25)
期刊：ONCOGENE
DOI：10.1038/s41388-024-03040-1
影響因子 ：8.0
引用產(chǎn)品： RPMI-1640 培養(yǎng)基 , DMEM高糖 培養(yǎng)基 , 293T [HEK-293T] 細(xì)胞 , A2780 細(xì)胞 , McCoy's 5A 培養(yǎng)基 , Hey 細(xì)胞 , SW626 細(xì)胞 , OVCAR-8 細(xì)胞 , SK-OV-3 細(xì)胞 , ES-2 細(xì)胞 , Caov-3 細(xì)胞
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ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis (2024-02-21)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-04980-8
影響因子 ：7.4
引用產(chǎn)品： OVCAR-8 細(xì)胞 , SK-OV-3 細(xì)胞 , ES-2 細(xì)胞
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USP33 facilitates the ovarian cancer progression via deubiquitinating and stabilizing CBX2 (2024-09-10)
期刊：ONCOGENE
DOI：10.1038/s41388-024-03151-9
影響因子 ：6.9
引用產(chǎn)品： 293T [HEK-293T] 細(xì)胞 , SK-OV-3 細(xì)胞 , Caov-3 細(xì)胞 , A2780 細(xì)胞 , Hey 細(xì)胞 , SW626 細(xì)胞 , ES-2 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞
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Enterolactone combined with m6A Reader IGF2BP3 inhibits malignant angiogenesis and disease progression in ovarian cancer (2024-12-21)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.156343
影響因子 ：6.7
引用產(chǎn)品： ES-2 細(xì)胞 , SK-OV-3 細(xì)胞
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Cannabidiol Inhibits Epithelial Ovarian Cancer: Role of Gut Microbiome (2024-04-11)
期刊：JOURNAL OF NATURAL PRODUCTS
DOI：10.1021/acs.jnatprod.3c00782
影響因子 ：5.1
引用產(chǎn)品： A2780 細(xì)胞 , ES-2 細(xì)胞
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CYP24A1 affected macrophage polarization through degradation of vitamin D as a candidate biomarker for ovarian cancer prognosis (2024-07-03)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112575
影響因子 ：4.8
引用產(chǎn)品： ES-2 細(xì)胞
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The roles of autophagy, ferroptosis and pyroptosis in the anti-ovarian cancer mechanism of harmine and their crosstalk (2024-03-18)
期刊：Scientific Reports
DOI：10.1038/s41598-024-57196-7
影響因子 ：4.6
引用產(chǎn)品： IOSE80 細(xì)胞 , SK-OV-3 細(xì)胞 , ES-2 細(xì)胞 , A2780 細(xì)胞
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SUGT1 regulates the progression of ovarian cancer through the AKT/PI3K/mTOR signaling pathway (2024-08-20)
期刊：Translational Oncology
DOI：10.1016/j.tranon.2024.102088
影響因子 ：4.5
引用產(chǎn)品： NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , ES-2 細(xì)胞
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CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells (2024-03-27)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-024-01393-5
影響因子 ：4.0
引用產(chǎn)品： Annexin V Binding Buffer (1×) , SK-OV-3 細(xì)胞 , Hey 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , A2780 細(xì)胞 , ES-2 細(xì)胞 , HO-8910 細(xì)胞 , IOSE-80 細(xì)胞
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Squalene monooxygenase (SQLE) protects ovarian cancer cells from ferroptosis (2024-09-30)
期刊：Scientific Reports
DOI：10.1038/s41598-024-72506-9
影響因子 ：3.8
引用產(chǎn)品： SK-OV-3 細(xì)胞 , IOSE-80 細(xì)胞 , A2780 細(xì)胞 , Hey 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , ES-2 細(xì)胞 , HO-8910 細(xì)胞
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METTL2B m3C RNA transferase: oncogenic role in ovarian cancer progression via regulation of the mTOR/AKT pathway and its link to the tumor immune microenvironment (2024-11-27)
期刊：BMC CANCER
DOI：10.1186/s12885-024-13225-2
影響因子 ：3.4
引用產(chǎn)品： ES-2 細(xì)胞 , 特級(jí)胎牛血清
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Identification and Validation of Prognostic Markers for Endometriosis-Associated Ovarian Cancer (2024-07-22)
期刊：International Journal of Medical Sciences
影響因子 ：3.2
引用產(chǎn)品： ES-2 細(xì)胞
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Placental extracellular vesicles induce ovarian tumour cell death in an ex vivo explant model: Possible therapeutic potential (2024-12-31)
期刊：PLACENTA
DOI：10.1016/j.placenta.2024.12.028
影響因子 ：3.0
引用產(chǎn)品： SK-OV-3 細(xì)胞 , ES-2 細(xì)胞 , 特級(jí)胎牛血清
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Suppression of KLF5 targets RREB1 to restrain the proliferation of ovarian cancer cells through ERK/MAPK signaling pathway (2024-12-11)
期刊：3 Biotech
DOI：10.1007/s13205-024-04171-8
影響因子 ：2.6
引用產(chǎn)品： A2780 細(xì)胞 , HO-8910 細(xì)胞 , SK-OV-3 細(xì)胞 , ES-2 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , CoC1 細(xì)胞
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Enterolactone and trabectedin suppress epithelial ovarian cancer synergistically via upregulating THBS1 (2023-07-13)
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.7942
影響因子 ：7.2
引用產(chǎn)品： A2780 細(xì)胞 , ES-2 細(xì)胞
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Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM) (2023-04-22)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-023-01156-8
影響因子 ：4.0
引用產(chǎn)品： SK-OV-3 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , ES-2 細(xì)胞 , A2780 細(xì)胞
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BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency (2022-10-05)
期刊：Nature Communications
DOI：10.1038/s41467-022-33323-8
影響因子 ：17.7
引用產(chǎn)品： ES-2 細(xì)胞
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PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib (2022-09-05)
期刊：Oxidative Medicine and Cellular Longevity
影響因子 ：7.3
引用產(chǎn)品： A2780 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , ES-2 細(xì)胞 , RPMI-1640 培養(yǎng)基 , 特級(jí)胎牛血清 , McCoy's 5A 培養(yǎng)基 , 增強(qiáng)型細(xì)胞活力檢測(cè)試劑盒 (CCK-8) , 碘化丙啶 (PI)染色液 (50μg/mL)
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Naringenin suppresses epithelial ovarian cancer by inhibiting proliferation and modulating gut microbiota (2022-08-19)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2022.154401
影響因子 ：6.7
引用產(chǎn)品： A2780 細(xì)胞 , ES-2 細(xì)胞
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CCNB1, Negatively Regulated by miR-559, Promotes the Proliferation, Migration, and Invasion of Ovarian Carcinoma Cells (2022-03-09)
期刊：Molecular Biotechnology
DOI：10.1007/s12033-022-00463-7
影響因子 ：2.6
引用產(chǎn)品： OV-90 細(xì)胞 , ES-2 細(xì)胞
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Circ_0021573 acts as a competing endogenous RNA to promote the malignant phenotypes of human ovarian cancer cells (2022-12-05)
期刊：Reproductive Biology
DOI：10.1016/j.repbio.2022.100704
影響因子 ：2.1
引用產(chǎn)品： SK-OV-3 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , A2780 細(xì)胞 , ES-2 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , RPMI-1640 培養(yǎng)基 , 特級(jí)胎牛血清 , 青霉素-鏈霉素溶液 (雙抗)，100×
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MiR-29c downregulates tumor-expressed B7-H3 to mediate the antitumor NK-cell functions in ovarian cancer (2021-04-17)
期刊：Gynecologic Oncology
DOI：10.1016/j.ygyno.2021.04.013
影響因子 ：4.7
引用產(chǎn)品： A2780 細(xì)胞 , 人卵巢上皮細(xì)胞 , SK-OV-3 細(xì)胞 , ES-2 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞
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RNA-binding protein IGF2BP2 enhances circ_0000745 abundancy and promotes aggressiveness and stemness of ovarian cancer cells via the microRNA-3187-3p/ERBB4/PI3K/AKT axis (2021-11-13)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-021-00917-7
影響因子 ：4.0
引用產(chǎn)品： CoC1 細(xì)胞 , SW626 細(xì)胞 , ES-2 細(xì)胞 , SK-OV-3 細(xì)胞
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miR?638 suppresses proliferation by negatively regulating high mobility group?A1 in ovarian cancer cells (2021-09-20)
期刊：Experimental and Therapeutic Medicine
影響因子 ：2.7
引用產(chǎn)品： A2780 細(xì)胞 , ES-2 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , Caov-3 細(xì)胞
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Suppressive activities of mangiferin on human epithelial ovarian cancer (2020-06-15)
期刊：Phytomedicine
DOI：10.1016/j.phymed.2020.153267
影響因子 ：7.9
引用產(chǎn)品： ES-2 細(xì)胞
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Overexpression of IGF2BP3 as a Potential Oncogene in Ovarian Clear Cell Carcinoma (2020-01-30)
期刊：Front Oncol
影響因子 ：5.7
引用產(chǎn)品： ES-2 細(xì)胞
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Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p (2020-02-24)
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-020-03704-y
影響因子 ：4.3
引用產(chǎn)品： ES-2 細(xì)胞 , McCoy's 5A 培養(yǎng)基 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞
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MiR-337–3p suppresses proliferation of epithelial ovarian cancer bytargeting PIK3CA and PIK3CB (2019-10-17)
期刊：Cancer Letters
DOI：10.1016/j.canlet.2019.10.021
影響因子 ：9.7
引用產(chǎn)品： A2780 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , SK-OV-3 細(xì)胞 , NIH:OVCAR-3 [OVCAR3] 細(xì)胞 , ES-2 細(xì)胞
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Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization (2017-05-08)
期刊：Oncogene
影響因子 ：8.0
引用產(chǎn)品： A2780 細(xì)胞 , SK-OV-3 細(xì)胞 , ES-2 細(xì)胞 , MCF7 [MCF-7] 細(xì)胞
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Enterolactone has stronger effects than enterodiol on ovarian cancer (2017-07-24)
期刊：Journal of Ovarian Research
影響因子 ：4.0
引用產(chǎn)品： ES-2 細(xì)胞
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Main components of pomegranate, ellagic acid and luteolin, inhibit metastasis of ovarian cancer by down-regulating MMP2 and MMP9 (2017-11-27)
期刊：Cancer Biology & Therapy
DOI：10.1080/15384047.2017.1394542
影響因子 ：3.6
引用產(chǎn)品： A2780 細(xì)胞 , ES-2 細(xì)胞
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