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TGFB1/TGFβ1/TGF-β1, Human, Recombinant

文獻(7) 說明書
一鍵復制產(chǎn)品信息
https://789.bio/ec/9KGd9G
  • https://789.bio/ec/9KGd9G
  • https://789.bio/ec/WuHhH0

英文名稱：TGFB1/TGFβ1/TGF-β1, Human, Recombinant

貨號： PCK091

價格： ￥14680 ￥6280 ￥3480 ￥1180 ￥23880

規(guī)格：
500μg 100μg 50μg 10μg 1mg

產(chǎn)品信息

產(chǎn)品形態(tài) 粉末
產(chǎn)品規(guī)格 500μg / 100μg / 50μg / 10μg / 1mg
別名 Transforming Growth Factor Beta-1;TGF-Beta-1;Latency-Associated Peptide;LAP;TGFB1;TGFB
物種 人
表達宿主 CHO Stable Cells
序列信息 Ala279-Ser390
檢索號 P01137
分子量 12.8 kDa
表觀分子量 13 kDa
生物活性 Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is 4-40 pg/mL.
純度 > 95% as determined by reducing SDS-PAGE.
內(nèi)毒素 < 1.0 EU per 1 μg as determined by LAL test.
儲存條件 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
運輸條件 Ambient temperature or ice pack.
有效期 12個月
制劑 Lyophilized from a 0.2 μm filtered solution of 50 mM Glycine-HCl, 150 mM Nacl, pH 2.5.
復融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
背景介紹 Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

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