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產(chǎn)品概述
| 名稱 | MH-S (小鼠肺泡巨噬細(xì)胞) (種屬鑒定正確) |
| 種屬 | 小鼠 |
| 生長特性 | 半貼半懸 |
| 細(xì)胞形態(tài) | 巨噬細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:5 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | The MH-S cell line was derived by SV40 transformation of an adherent cell enriched population of mouse alveolar macrophages. |
| 年齡（性別） | 雄性；7周齡 |
| 組織來源 | 肺巨噬細(xì)胞 |
| 細(xì)胞類型 | 轉(zhuǎn)化細(xì)胞系 |
| 生物安全等級(jí) | BSL-2 |
| 抗原表達(dá)情況 | CD11b (Mac-1); Class II antigens (I-A); T antigen |
| 基因表達(dá)情況 | interleukin 1 (IL-1) |
| 保藏機(jī)構(gòu) | ATCC; CRL-2019 BCRC; 60419 ECACC; 95090612 |
STR鑒定
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STR位點(diǎn)信息
18-3 16 6-7 15 5-5 17 X-1 26,27 1-2 19 7-1 26.2 8-1 16 1-1 16 19-2 13 15-3 22.3 12-1 17 6-4 18 4-2 20.3 3-2 14 2-1 16 13-1 17.1,18.1
11-2 16 17-2 15 -
STR鑒定圖
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參考文獻(xiàn)
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Bletilla striata polysaccharides alleviate ARDS by inhibiting NETs-induced pyroptosis in pulmonary alveolar macrophage through the PAD4 pathway (2025-02-13)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2025.141026
影響因子 ：7.7
引用產(chǎn)品： MH-S 細(xì)胞
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Sanzi Yangqin Decoction improved acute lung injury by regulating the TLR2-mediated NF-κB/NLRP3 signaling pathway and inhibiting the activation of NLRP3 inflammasome (2025-01-31)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2025.156438
影響因子 ：6.7
引用產(chǎn)品： MH-S 細(xì)胞 , 特級(jí)胎牛血清
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Electroacupuncture promotes resolution of inflammation by modulating SPMs via vagus nerve activation in LPS-induced ALI (2025-01-01)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113941
影響因子 ：4.8
引用產(chǎn)品： MH-S 細(xì)胞
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Development of tanshinone IIA chitosan nanoparticles via chitosan solid dispersion for improving the therapeutical effects (2025-02-25)
期刊：JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI：10.1016/j.jddst.2025.106752
影響因子 ：4.5
引用產(chǎn)品： MH-S 細(xì)胞
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The injury effect of osteopontin in sepsis-associated lung injury (2025-01-24)
期刊：Journal of Inflammation-London
DOI：10.1186/s12950-025-00430-4
影響因子 ：4.4
引用產(chǎn)品： MH-S 細(xì)胞
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Sono-Triggered Biomimetically Nanoantibiotics Mediate Precise Sequential Therapy of MRSA-Induced Lung Infection (2024-09-30)
期刊：ADVANCED MATERIALS
影響因子 ：27.4
引用產(chǎn)品： MH-S 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Nebulized inhalation of nintedanib-loaded biomimetic nano-liposomes attenuated bleomycin-induced interstitial lung fibrosis in mice (2024-05-08)
期刊：Nano Today
DOI：10.1016/j.nantod.2024.102298
影響因子 ：17.4
引用產(chǎn)品： MH-S 細(xì)胞
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Gut-derived memory γδ T17 cells exacerbate sepsis-induced acute lung injury in mice (2024-08-07)
期刊：Nature Communications
DOI：10.1038/s41467-024-51209-9
影響因子 ：14.7
引用產(chǎn)品： RAW 264.7 細(xì)胞 , MH-S 細(xì)胞 , A549 [A-549] 細(xì)胞
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Carbon nitride nanosheets induce pulmonary surfactant deposition via dysfunction of alveolar secretion and clearance (2024-08-27)
期刊：Nano Today
DOI：10.1016/j.nantod.2024.102457
影響因子 ：13.2
引用產(chǎn)品： MH-S 細(xì)胞 , β-巰基乙醇（55 mM），1000×
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NLRP3 inflammasome mediates pyroptosis of alveolar macrophages to induce radiation lung injury (2024-12-01)
期刊：JOURNAL OF HAZARDOUS MATERIALS
DOI：10.1016/j.jhazmat.2024.136740
影響因子 ：12.2
引用產(chǎn)品： MH-S 細(xì)胞
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Pulmonary Surfactant Biogenesis Blockage Mediated Polyhexamethylene Guanidine Disinfectant Induced Pulmonary Fibrosis (2024-10-28)
期刊：JOURNAL OF HAZARDOUS MATERIALS
DOI：10.1016/j.jhazmat.2024.136307
影響因子 ：12.2
引用產(chǎn)品： MH-S 細(xì)胞
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ROS-responsive nanoparticles for bioimaging and treating acute lung injury by releasing dexamethasone and improving alveolar macrophage homeostasis (2024-11-22)
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-024-03015-0
影響因子 ：10.6
引用產(chǎn)品： MH-S 細(xì)胞
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PD-L1 upregulation in activated fibroblasts promotes silica particle-induced pulmonary fibrosis (2024-12-23)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.139147
影響因子 ：7.7
引用產(chǎn)品： MH-S 細(xì)胞
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FAP expression dynamics and role in silicosis: Insights from epidemiological and experimental models (2024-06-03)
期刊：ENVIRONMENTAL POLLUTION
DOI：10.1016/j.envpol.2024.124311
影響因子 ：7.6
引用產(chǎn)品： MH-S 細(xì)胞
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Polyhexamethylene guanidine accelerates the macrophage foamy formation mediated pulmonary fibrosis (2024-02-13)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116084
影響因子 ：6.8
引用產(chǎn)品： MH-S 細(xì)胞 , NIH/3T3 細(xì)胞
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S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting fatty acid metabolism (2024-12-06)
期刊：eLife
影響因子 ：6.4
引用產(chǎn)品： MH-S 細(xì)胞
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Glycolytic reprogramming governs crystalline silica-induced pyroptosis and inflammation through promoting lactylation modification (2024-08-31)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116952
影響因子 ：6.2
引用產(chǎn)品： MH-S 細(xì)胞
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Schistosoma japonicum cystatin alleviates paraquat poisoning caused acute lung injury in mice through activating regulatory macrophages (2024-06-20)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116615
影響因子 ：6.2
引用產(chǎn)品： β-巰基乙醇（55 mM），1000× , MH-S 細(xì)胞 , 特級(jí)胎牛血清
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Multi-omics and multi-stages integration identified a novel variant associated with silicosis risk (2024-05-29)
期刊：ARCHIVES OF TOXICOLOGY
DOI：10.1007/s00204-024-03795-2
影響因子 ：6.1
引用產(chǎn)品： MH-S 細(xì)胞
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GLP-1R activation attenuates the progression of pulmonary fibrosis via disrupting NLRP3 inflammasome/PFKFB3-driven glycolysis interaction and histone lactylation (2024-10-21)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05753-z
影響因子 ：6.1
引用產(chǎn)品： MH-S 細(xì)胞
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A Flavonoid Glycoside Compound from Siraitia grosvenorii with Anti-Inflammatory and Hepatoprotective Effects In Vitro (2024-04-07)
期刊：Biomolecules
影響因子 ：5.5
引用產(chǎn)品： 青霉素-鏈霉素溶液（雙抗），100× , Hep G2 細(xì)胞 , 特級(jí)胎牛血清 , RPMI-1640 培養(yǎng)基 , 磷酸鹽緩沖液（PBS） 1× , MEM（含NEAA） 培養(yǎng)基 , 0.25%胰蛋白酶溶液（含EDTA，溶于PBS） , MH-S 細(xì)胞
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ANGPTL2 knockdown induces autophagy to relieve alveolar macrophage pyroptosis by reducing LILRB2-mediated inhibition of TREM2 (2024-05-17)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 ：5.3
引用產(chǎn)品： MH-S細(xì)胞專用培養(yǎng)基 , MH-S 細(xì)胞
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Esaxerenone Inhibits Interferon-γ Induced Pyroptosis of Macrophages in the Lungs of Aldosterone-treated Mice (2024-05-07)
期刊：INFLAMMATION
DOI：10.1007/s10753-024-02030-5
影響因子 ：5.1
引用產(chǎn)品： RAW 264.7 細(xì)胞 , MH-S 細(xì)胞
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Bexarotene ameliorated the pulmonary inflammation and M1 polarization of alveolar macrophages induced by cigarette smoke via PPARγ/HO-1 (2024-12-18)
期刊：RESPIRATORY RESEARCH
DOI：10.1186/s12931-024-03064-x
影響因子 ：4.7
引用產(chǎn)品： MH-S 細(xì)胞
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The Protective Effects of Ganoderma lucidum Active Peptide GLP4 on Lung Injury Induced by Cadmium Poisoning in Mice (2024-05-22)
期刊：Toxics
影響因子 ：4.6
引用產(chǎn)品： MH-S 細(xì)胞
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Discovery of the Active Compounds of the Ethyl Acetate Extract Site of Ardisia japonica (Thunb.) Blume for the Treatment of Acute Lung Injury (2024-02-07)
期刊：MOLECULES
影響因子 ：4.6
引用產(chǎn)品： MH-S 細(xì)胞
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Electroacupuncture pretreatment maintains mitochondrial quality control via HO-1/MIC60 signaling pathway to alleviate endotoxin-induced acute lung injury (2024-08-30)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2024.167480
影響因子 ：4.2
引用產(chǎn)品： MH-S 細(xì)胞
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GATA2 downregulation contributes to pro-inflammatory phenotype and defective phagocytosis of pulmonary macrophages in chronic obstructive pulmonary disease (2024-10-07)
期刊：Aging-US
影響因子 ：3.9
引用產(chǎn)品： MH-S 細(xì)胞 , RAW 264.7 細(xì)胞
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Aquaporin 1 aggravates lipopolysaccharide-induced macrophage polarization and pyroptosis (2024-08-10)
期刊：Scientific Reports
DOI：10.1038/s41598-024-68899-2
影響因子 ：3.8
引用產(chǎn)品： MH-S細(xì)胞專用培養(yǎng)基 , MH-S 細(xì)胞
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Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages (2024-05-16)
期刊：PLoS One
DOI：10.1371/journal.pone.0303556
影響因子 ：3.7
引用產(chǎn)品： RPMI-1640 培養(yǎng)基 , 特級(jí)胎牛血清 , β-巰基乙醇（55 mM），1000× , MH-S細(xì)胞專用培養(yǎng)基 , MH-S 細(xì)胞 , 青霉素-鏈霉素溶液（雙抗），100×
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ATF3 deficiency promotes alveolar macrophage pyroptosis in sepsis-induced acute lung injury (2024-11-25)
期刊：MOLECULAR IMMUNOLOGY
DOI：10.1016/j.molimm.2024.11.004
影響因子 ：3.2
引用產(chǎn)品： MH-S 細(xì)胞
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Single-dose of hybrid eukaryotic-prokaryotic nanovesicles to drive a rapid and controllable immune response against Klebsiella pneumoniae induced nosocomial pneumonia (2023-12-28)
期刊：Nano Today
DOI：10.1016/j.nantod.2023.102135
影響因子 ：17.4
引用產(chǎn)品： MH-S 細(xì)胞
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Ythdf2 promotes pulmonary hypertension by suppressing Hmox1-dependent anti-inflammatory and antioxidant function in alveolar macrophages (2023-02-15)
期刊：Redox Biology
DOI：10.1016/j.redox.2023.102638
影響因子 ：11.4
引用產(chǎn)品： MH-S 細(xì)胞
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Naringin alleviates pneumonia caused by Klebsiella pneumoniae infection by suppressing NLRP3 inflammasome (2023-12-18)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.116028
影響因子 ：7.5
引用產(chǎn)品： MH-S 細(xì)胞
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Uncovering mechanisms of Baojin Chenfei formula treatment for silicosis by inhibiting inflammation and fibrosis based on serum pharmacochemistry and network analysis (2023-05-29)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115082
影響因子 ：6.8
引用產(chǎn)品： HFL1 細(xì)胞 , MH-S 細(xì)胞 , Ham's F-12K 培養(yǎng)基 , 青霉素-鏈霉素溶液 (雙抗)，100×
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5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway (2023-07-17)
期刊：INFLAMMATION RESEARCH
DOI：10.1007/s00011-023-01769-1
影響因子 ：6.7
引用產(chǎn)品： MH-S 細(xì)胞
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Therapeutic Effect and Safety Evaluation of Naringin on Klebsiella pneumoniae in Mice (2023-11-03)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.6
引用產(chǎn)品： MH-S 細(xì)胞
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MiR-223-3p attenuates radiation-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages (2023-07-16)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110616
影響因子 ：5.6
引用產(chǎn)品： MH-S 細(xì)胞
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Cordyceps militaris Solid Medium Extract Alleviates Lipoteichoic Acid-Induced MH-S Inflammation by Inhibiting TLR2/NF-κB/NLRP3 Pathways (2023-10-24)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.6
引用產(chǎn)品： MH-S 細(xì)胞
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4-octyl itaconate ameliorates alveolar macrophage pyroptosis against ARDS via rescuing mitochondrial dysfunction and suppressing the cGAS/STING pathway (2023-03-31)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110104
影響因子 ：5.6
引用產(chǎn)品： MH-S 細(xì)胞
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A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages (2023-09-21)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110965
影響因子 ：5.6
引用產(chǎn)品： MH-S 細(xì)胞
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Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD (2023-12-02)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影響因子 ：5.4
引用產(chǎn)品： MH-S 細(xì)胞
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Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary alveolar macrophage pyroptosis (2023-10-28)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影響因子 ：5.4
引用產(chǎn)品： MH-S 細(xì)胞
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IRF4 Participates in Pulmonary Fibrosis Induced by Silica Particles through Regulating Macrophage Polarization and Fibroblast Activation (2023-11-08)
期刊：INFLAMMATION
DOI：10.1007/s10753-023-01890-7
影響因子 ：5.1
引用產(chǎn)品： MH-S 細(xì)胞
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Xuanfei Baidu Decoction suppresses complement overactivation and ameliorates IgG immune complex-induced acute lung injury by inhibiting JAK2/STAT3/SOCS3 and NF-κB signaling pathway (2022-11-21)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2022.154551
影響因子 ：6.7
引用產(chǎn)品： MH-S 細(xì)胞
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Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS-induced inflammation in vitro and in vivo (2022-09-23)
期刊：Food Science & Nutrition
影響因子 ：3.6
引用產(chǎn)品： MH-S 細(xì)胞
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Effective-components combination improves airway remodeling in COPD rats by suppressing M2 macrophage polarization via the inhibition of mTORC2 activity (2021-09-13)
期刊：Phytomedicine
DOI：10.1016/j.phymed.2021.153759
影響因子 ：7.9
引用產(chǎn)品： MH-S 細(xì)胞
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Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection (2021-03-22)
期刊：Frontiers in Cellular and Infection Microbiology
影響因子 ：5.5
引用產(chǎn)品： MH-S 細(xì)胞 , RAW 264.7 細(xì)胞
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Transforming Growth Factor-β1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis (2021-08-24)
期刊：Frontiers in Cellular and Infection Microbiology
影響因子 ：5.5
引用產(chǎn)品： MH-S 細(xì)胞
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MicroRNA-205-5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2-mediated Beclin1 ubiquitination (2021-08-27)
期刊：Journal Of Cellular And Molecular Medicine
影響因子 ：5.3
引用產(chǎn)品： MH-S 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Upregulated expression of long non-coding RNA MEG3 serves as a prognostic biomarker in severe pneumonia children and its regulatory mechanism (2021-09-24)
期刊：Bioengineered
DOI：10.1080/21655979.2021.1979351
影響因子 ：4.9
引用產(chǎn)品： MH-S 細(xì)胞
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3-O-trans-caffeoyloleanolic acid improves acute lung injury via anti-inflammation and antioxidative stress-involved PI3K/AKT pathway (2021-05-19)
期刊：Chemical Biology & Drug Design
影響因子 ：2.9
引用產(chǎn)品： MH-S 細(xì)胞
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LncRNA NEAT1 Knockdown Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulation of miR-182-5p/WISP1 Axis (2021-05-27)
期刊：Biochemical Genetics
DOI：10.1007/s10528-021-10081-8
影響因子 ：2.4
引用產(chǎn)品： MH-S 細(xì)胞 , RPMI-1640完全培養(yǎng)基 (含10%FBS)
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