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產(chǎn)品概述
名稱(chēng) | SV40 MES 13 (小鼠腎小球系膜細(xì)胞) (種屬鑒定正確) |
別稱(chēng) | SV40-MES13; MES-13; MES 13; MES13 |
種屬 | 小鼠 |
生長(zhǎng)特性 | 貼壁細(xì)胞 |
細(xì)胞形態(tài) | 成纖維細(xì)胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:3-1:8 |
推薦換液頻率 | 2-3次/周 |
背景描述 | SV40 MES 13細(xì)胞的細(xì)胞骨架染色突出呈現(xiàn)肌動(dòng)蛋白,在細(xì)胞質(zhì)中有豐富的平行微絲。有報(bào)道稱(chēng),在1uM血管緊張素Ⅱ存在下,SV40 MES 13細(xì)胞會(huì)收縮。SV40 MES 13細(xì)胞在軟瓊脂中形成克??;SV40大T抗原陽(yáng)性。 |
年齡(性別) | 7-10周齡 |
組織來(lái)源 | 腎小球系膜細(xì)胞 |
細(xì)胞類(lèi)型 | 轉(zhuǎn)化細(xì)胞系 |
生物安全等級(jí) | BSL-2 |
倍增時(shí)間 | ~26 hours |
保藏機(jī)構(gòu) | ATCC; CRL-1927 |
STR鑒定
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STR位點(diǎn)信息
18-3 16 6-7 12 5-5 14,17 X-1 28 1-2 13,19 7-1 25.2 8-1 16 1-1 17 19-2 13 15-3 22.3 12-1 17 6-4 15.1 4-2 20.3 3-2 14 2-1 9,16 13-1 16.2,17.1
11-2 16 17-2 15 -
STR鑒定圖
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參考文獻(xiàn)
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tRF3-IleAAT reduced extracellular matrix synthesis in diabetic kidney disease mice by targeting ZNF281 and inhibiting ferroptosis (2024-01-29)
期刊:ACTA PHARMACOLOGICA SINICA
DOI:10.1038/s41401-024-01228-5
影響因子 :8.2
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Diminished nuclear-localized β-adrenoceptor signalling activates YAP to promote kidney fibrosis in diabetic nephropathy (2024-10-02)
期刊:BRITISH JOURNAL OF PHARMACOLOGY
影響因子 :6.8
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Integrative transcriptome analysis reveals Serpine2 promotes glomerular mesangial cell proliferation and extracellular matrix accumulation via activating ERK1/2 signalling pathway in diabetic nephropathy (2024-11-18)
期刊:DIABETES OBESITY & METABOLISM
影響因子 :5.4
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Puerarin alleviates the high glucose-induced oxidative stress via the RAGE/PKC/NOX4 axis in renal mesangial cells (2024-11-01)
期刊:JOURNAL OF TOXICOLOGICAL SCIENCES
影響因子 :1.8
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Huanglian Decoction treats Henoch-Schonlein purpura nephritis by inhibiting NF-κB/NLRP3 signaling pathway and reducing renal IgA deposition (2024-04-08)
期刊:ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
DOI:10.1590/0001-3765202420220970
影響因子 :1.3
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Circ-0000953 deficiency exacerbates podocyte injury and autophagy disorder by targeting Mir665-3p-Atg4b in diabetic nephropathy (2023-12-03)
期刊:Autophagy
DOI:10.1080/15548627.2023.2286128
影響因子 :13.3
引用產(chǎn)品: 小鼠腎小管上皮細(xì)胞 , SV40 MES 13 細(xì)胞 , 小鼠腎動(dòng)脈內(nèi)皮細(xì)胞
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ASH2L-mediated H3K4me3 drives diabetic nephropathy through HIPK2 and Notch1 pathway (2023-10-23)
期刊:Translational Research
DOI:10.1016/j.trsl.2023.10.002
影響因子 :7.8
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Seven new triterpenoid saponins from Astragalus membranaceus var. mongholicus and the inhibition of high-glucose induced SV40 MES 13 cells (2023-04-07)
期刊:NEW JOURNAL OF CHEMISTRY
影響因子 :3.3
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Cornuside inhibits glucose-induced proliferation and inflammatory response of mesangial cells (2023-11-01)
期刊:KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
DOI:10.4196/kjpp.2023.27.6.513
影響因子 :2.0
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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ASH2L Aggravates Fibrosis and Inflammation through HIPK2 in High Glucose-Induced Glomerular Mesangial Cells (2022-11-29)
期刊:Genes
影響因子 :4.1
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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LncRNA Dlx6os1 Accelerates Diabetic Nephropathy Progression by Epigenetically Repressing SOX6 via Recruiting EZH2 (2022-01-17)
期刊:Kidney Blood Press Res
影響因子 :2.8
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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METTL3 enhances NSD2 mRNA stability to reduce renal impairment and interstitial fibrosis in mice with diabetic nephropathy (2022-03-30)
期刊:BMC Nephrology
DOI:10.1186/s12882-022-02753-3
影響因子 :2.3
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway. (2021-11-05)
期刊:Frontiers in Cell and Developmental Biology
影響因子 :5.5
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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CircSMAD4 alleviates high glucose-induced inflammation, extracellular matrix deposition and apoptosis in mouse glomerulus mesangial cells by relieving miR-377-3p-mediated BMP7 inhibition (2021-11-20)
期刊:Diabetology & Metabolic Syndrome
DOI:10.1186/s13098-021-00753-1
影響因子 :4.8
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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Rosiglitazone attenuates high glucose-induced proliferation, inflammation, oxidative stress and extracellular matrix accumulation in mouse mesangial cells through the Gm26917/miR-185-5p pathway (2021-03-30)
期刊:Endocrine Journal
影響因子 :2.9
引用產(chǎn)品: SV40 MES 13 細(xì)胞 , DMEM高糖 培養(yǎng)基 , Ham's F-12 培養(yǎng)基 , 特級(jí)胎牛血清
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miR-1968-5p is involved in the pathogenesis of lupus nephritis of NZBWF1 mice by targeting csf1 (2021-07-06)
期刊:Clinical and Experimental Nephrology
DOI:10.1007/s10157-021-02091-y
影響因子 :2.3
引用產(chǎn)品: SV40 MES 13 細(xì)胞
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