產(chǎn)品中心Cell Resources
聯(lián)系我們CONTACT US
400-999-210024小時(shí)服務(wù)熱線
產(chǎn)品概述
| 名稱 | HCCC-9810 (人膽管細(xì)胞型肝癌細(xì)胞) (STR鑒定正確) |
| 別稱 | HCCC9810; Hccc9810 |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | HCCC-9810細(xì)胞源自一位女性肝膽管細(xì)胞癌患者，呈上皮細(xì)胞樣。HCCC-9810細(xì)胞染色體模式數(shù)為71，但其染色體數(shù)目可以在22-117的范圍內(nèi)變動(dòng)。HCCC-9810細(xì)胞倍增時(shí)間為20.4小時(shí)；細(xì)胞內(nèi)AFP、CEA和CA19-9的分泌水平低，HCCC-9810細(xì)胞在裸鼠中的成瘤率為20%。 |
| 年齡（性別） | 女性 |
| 組織來(lái)源 | 肝膽管細(xì)胞癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 肝膽癌細(xì)胞 |
| 致瘤性 | Yes, in nude mice. |
STR鑒定
-
STR位點(diǎn)信息
Amelogenin X CSF1PO 11,12 D2S1338 17,19 D3S1358 17 D5S818 11 D7S820 10,12 D8S1179 10,13 D13S317 11 D16S539 9,12 D18S51 15 D19S433 13,14 D21S11 30,32 FGA 23,24 PentaD 9,13 PentaE 19 TH01 9 TPOX 8,11 vWA 16,17 D6S1043 19 D12S391 19 D2S441 12 -
STR鑒定圖
-
參考文獻(xiàn)
-
Platelets promote metastasis of intrahepatic cholangiocarcinoma through activation of TGF-β/Smad2 pathway (2025-02-18)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2025.167734
影響因子 ：4.2
引用產(chǎn)品： HCCC-9810 細(xì)胞 , HuCC-T1 細(xì)胞
-
SQSTM1/p62 confers resistance of intrahepatic cholangiocarcinoma cells to 5-Fluorouracil by promoting Nrf2 nuclear translocation (2025-01-04)
期刊：Molecular & Cellular Toxicology
DOI：10.1007/s13273-024-00495-x
影響因子 ：1.1
引用產(chǎn)品： HCCC-9810 細(xì)胞 , 青霉素-鏈霉素溶液（雙抗），100×
-
AMDHD1 acts as a tumor suppressor and contributes to activation of TGF-β signaling pathway in cholangiocarcinoma (2024-08-14)
期刊：CELL DEATH AND DIFFERENTIATION
DOI：10.1038/s41418-024-01361-y
影響因子 ：13.7
引用產(chǎn)品： RBE 細(xì)胞 , HCCC-9810 細(xì)胞 , CCLP-1 細(xì)胞 , HuCC-T1 細(xì)胞 , QBC939 細(xì)胞 , SNU-869 細(xì)胞
-
CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis (2024-12-18)
期刊：CANCER RESEARCH
DOI：10.1158/0008-5472.CAN-24-0147
影響因子 ：12.5
引用產(chǎn)品： HuCC-T1 細(xì)胞 , RBE 細(xì)胞 , HCCC-9810 細(xì)胞 , Hep 3B2.1-7 細(xì)胞 , HFL1 細(xì)胞 , HuH-1 細(xì)胞 , HuH-7 細(xì)胞
-
The heterogeneity of signaling pathways and drug responses in intrahepatic cholangiocarcinoma with distinct genetic mutations (2024-01-11)
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-06406-7
影響因子 ：9.0
引用產(chǎn)品： HCCC-9810 細(xì)胞
-
ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-β signaling (2024-06-14)
期刊：Translational Oncology
DOI：10.1016/j.tranon.2024.102035
影響因子 ：4.5
引用產(chǎn)品： HuCC-T1 細(xì)胞 , RBE 細(xì)胞 , HCCC-9810 細(xì)胞
-
Protein regulator of cytokinesis 1 accentuates cholangiocarcinoma progression via mTORC1-mediated glycolysis (2024-02-28)
期刊：Human Cell
DOI：10.1007/s13577-024-01032-7
影響因子 ：4.3
引用產(chǎn)品： HCCC-9810 細(xì)胞 , HuCC-T1 細(xì)胞 , RBE 細(xì)胞
-
UBA3 promotes the occurrence and metastasis of intrahepatic cholangiocarcinoma through MAPK signaling pathway: UBA3 promotes the occurrence and metastasis of ICC (2024-01-31)
期刊：ACTA BIOCHIMICA ET BIOPHYSICA SINICA
影響因子 ：3.3
引用產(chǎn)品： HCCC-9810 細(xì)胞 , RBE 細(xì)胞 , QBC939 細(xì)胞 , HuCC-T1 細(xì)胞
-
Huaier inhibits cholangiocarcinoma cells through the twist1/FBP1/Wnt/β-catenin axis (2024-07-23)
期刊：MOLECULAR BIOLOGY REPORTS
DOI：10.1007/s11033-024-09738-5
影響因子 ：2.6
引用產(chǎn)品： HCCC-9810 細(xì)胞 , RBE 細(xì)胞
-
Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib (2024-03-28)
期刊：Discover Oncology
DOI：10.1007/s12672-024-00947-9
影響因子 ：2.2
引用產(chǎn)品： HCCC-9810 細(xì)胞
-
METTL3-mediated m6A modification promotes chemoresistance of intrahepatic cholangiocarcinoma by up-regulating NRF2 to inhibit ferroptosis in cisplatin-resistant cells (2024-11-01)
期刊：JOURNAL OF CHEMOTHERAPY
DOI：10.1080/1120009X.2024.2421700
影響因子 ：1.9
引用產(chǎn)品： HuCC-T1 細(xì)胞 , RPMI-1640 培養(yǎng)基 , 特級(jí)胎牛血清 , HCCC-9810 細(xì)胞 , 青霉素-鏈霉素溶液（雙抗），100×
-
Development of potent antibody drug conjugates against ICAM1+ cancer cells in preclinical models of cholangiocarcinoma (2023-09-16)
期刊：npj Precision Oncology
DOI：10.1038/s41698-023-00447-z
影響因子 ：7.9
引用產(chǎn)品： HuCC-T1 細(xì)胞 , HCCC-9810 細(xì)胞
-
Circ_0020256 induces fibroblast activation to drive cholangiocarcinoma development via recruitment of EIF4A3 protein to stabilize KLF4 mRNA (2023-05-13)
期刊：Cell Death Discovery
DOI：10.1038/s41420-023-01439-5
影響因子 ：7.0
引用產(chǎn)品： HCCC-9810 細(xì)胞 , RBE 細(xì)胞
-
Oncogenic Role of the NFATC2/NEDD4/FBP1 Axis in Cholangiocarcinoma (2023-06-05)
期刊：LABORATORY INVESTIGATION
DOI：10.1016/j.labinv.2023.100193
影響因子 ：5.0
引用產(chǎn)品： RBE 細(xì)胞 , HCCC-9810 細(xì)胞
-
Identification of SPRYD4 as a tumour suppressor predicts prognosis and correlates with immune infiltration in cholangiocarcinoma (2023-05-04)
期刊：BMC CANCER
DOI：10.1186/s12885-023-10810-9
影響因子 ：3.8
引用產(chǎn)品： HuCC-T1 細(xì)胞 , RBE 細(xì)胞 , CCLP-1 細(xì)胞 , huh28 細(xì)胞 , QBC939 細(xì)胞 , HCCC-9810 細(xì)胞
-
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42 (2023-03-26)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2023.116492
影響因子 ：3.8
引用產(chǎn)品： 特級(jí)胎牛血清 , 青霉素-鏈霉素溶液 (雙抗)，100× , HCCC-9810 細(xì)胞 , 人肝內(nèi)膽管上皮細(xì)胞 , 人肝內(nèi)膽管上皮細(xì)胞完全培養(yǎng)基
-
METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10 (2022-12-07)
期刊：Cancer Cell International
DOI：10.1186/s12935-022-02809-2
影響因子 ：6.4
引用產(chǎn)品： RBE 細(xì)胞 , HCCC-9810 細(xì)胞
-
7-Methoxy-13-dehydroxypaxilline: New indole diterpenoid from an endophytic fungus Penicillium sp. Nb 19 (2022-08-05)
期刊：NATURAL PRODUCT RESEARCH
DOI：10.1080/14786419.2022.2107639
影響因子 ：2.5
引用產(chǎn)品： MCF7 [MCF-7] 細(xì)胞 , Hep G2 細(xì)胞 , HCCC-9810 細(xì)胞
-
Circ_0000284 facilitates the growth, metastasis and glycolysis of intrahepatic cholangiocarcinoma through miR-152-3p-mediated PDK1 expression. (2022-11-04)
期刊：HISTOLOGY AND HISTOPATHOLOGY
影響因子 ：2.1
引用產(chǎn)品： RBE 細(xì)胞 , HCCC-9810 細(xì)胞 , 人肝內(nèi)膽管上皮細(xì)胞
-
LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis (2021-02-08)
期刊：Bmc Cancer
DOI：10.1186/s12885-021-07838-0
影響因子 ：3.8
引用產(chǎn)品： HCCC-9810 細(xì)胞 , RBE 細(xì)胞
-
Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma (2020-11-10)
期刊：Aging-US
影響因子 ：5.2
引用產(chǎn)品： HCCC-9810 細(xì)胞 , RBE 細(xì)胞
-
Curcumol Exerts Anticancer Effect in Cholangiocarcinoma Cells via Down-Regulating CDKL3 (2018-03-20)
期刊：Frontiers in Physiology
影響因子 ：4.0
引用產(chǎn)品： HCCC-9810 細(xì)胞
-
Unique Responses of Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines toward Cantharidin and Norcantharidin (2018-05-25)
期刊：Journal of Cancer
影響因子 ：3.9
引用產(chǎn)品： HCCC-9810 細(xì)胞 , RBE 細(xì)胞
FAQs
Q：{{item.question}}
A：
產(chǎn)品資料
識(shí)別碼示意圖
娜胡文君.png "邱國(guó)娜/胡文君")
.png "梅文強(qiáng)")
