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BSF-2, Human, Recombinant
一鍵復(fù)制產(chǎn)品信息

貨號：PCK085

價(jià)格：￥8802780968013880

規(guī)格：

10μg

10μg
50μg
500μg
1mg

數(shù)量： - +

說明書

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產(chǎn)品概述

產(chǎn)品信息

別名	IFN-β2, B-Cell Differentiation Factor (BCDF), BSF-2, HPGF, HSF, MGI-2
物種	Human
表達(dá)宿主	E.coli
序列信息	MVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM with polyhistidine tag at the C-terminus.
檢索號	P05231.1
分子量	21.8 kDa
表觀分子量	22 kDa
標(biāo)簽	His-tag?at?the?C-terminus
生物活性	Measure by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is <0.5 ng/mL. The specific activity of recombinant human IL-6 is approximately >5 x 10^8 IU/mg.Measure by its ability to induce proliferation in MCF-7 cells. The ED50 for this effect is <4.4 ng/mL.

產(chǎn)品特性

純度	>98% as determined by SDS-PAGE. Ni-NTA chromatography
內(nèi)毒素	<0.1 EU per 1 μg of the protein by the LAL method.
保存	Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution, store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1% BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
運(yùn)輸	Ambient temperature or ice pack.
制劑	The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 8.0.
復(fù)融	It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

背景介紹

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory myokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10.

參考文獻(xiàn)

文獻(xiàn)列表

Stereotactic body radiation therapy suppresses myeloid-derived suppressor cells by regulating miR-21/Sorbin and SH3 Domain-containing Protein 1 axis (2024-06-14)

期刊：HUMAN & EXPERIMENTAL TOXICOLOGY

DOI：10.1177/09603271241261307

影響因子：2.7

引用產(chǎn)品： GM-CSF/CSF2 (C-6His), Mouse, Recombinant , 特級胎牛血清 , IL-6/IFN-β2/BSF-2, Human, Recombinant , 丙酮酸鈉溶液（100 mM），100×
Mast cell-derived exosomal miR-181a-5p modulated trophoblast cell viability, migration, and invasion via YY1/MMP-9 axis (2022-06-13)

期刊：JOURNAL OF CLINICAL LABORATORY ANALYSIS

DOI：10.1002/jcla.24549

影響因子：3.1

引用產(chǎn)品： SCF/c-Kit/KIT ligand, Human, Recombinant , IL-6/IFN-β2/BSF-2, Human, Recombinant , 人皮膚肥大細(xì)胞完全培養(yǎng)基 , 293T [HEK-293T] 細(xì)胞